210 related articles for article (PubMed ID: 8609372)
1. Cytotoxicity of KDEL-terminated ricin toxins correlates with distribution of the KDEL receptor in the Golgi.
Tagge E; Chandler J; Tang BL; Hong W; Willingham MC; Frankel A
J Histochem Cytochem; 1996 Feb; 44(2):159-65. PubMed ID: 8609372
[TBL] [Abstract][Full Text] [Related]
2. Modification of ricin A chain, by addition of endoplasmic reticulum (KDEL) or Golgi (YQRL) retention sequences, enhances its cytotoxicity and translocation.
Zhan J; Stayton P; Press OW
Cancer Immunol Immunother; 1998 Mar; 46(1):55-60. PubMed ID: 9520293
[TBL] [Abstract][Full Text] [Related]
3. Generation of a potent chimeric toxin by replacement of domain III of Pseudomonas exotoxin with ricin A chain KDEL.
Pitcher C; Roberts L; Fawell S; Zdanovsky AG; FitzGerald DJ; Lord JM
Bioconjug Chem; 1995; 6(5):624-9. PubMed ID: 8974463
[TBL] [Abstract][Full Text] [Related]
4. Addition of an endoplasmic reticulum retrieval sequence to ricin A chain significantly increases its cytotoxicity to mammalian cells.
Wales R; Roberts LM; Lord JM
J Biol Chem; 1993 Nov; 268(32):23986-90. PubMed ID: 8226941
[TBL] [Abstract][Full Text] [Related]
5. Construction and characterization of the recombinant immunotoxin RTA-4D5-KDEL targeting HER2/neu-positive cancer cells and locating the endoplasmic reticulum.
Jiao P; Zhang J; Dong Y; Wei D; Ren Y
Appl Microbiol Biotechnol; 2018 Nov; 102(22):9585-9594. PubMed ID: 30141083
[TBL] [Abstract][Full Text] [Related]
6. A trans-Golgi network retention signal YQRL fused to ricin A chain significantly enhances its cytotoxicity.
Zhan J; Ge L; Shen J; Wang K; Zheng S
Biochem Biophys Res Commun; 2004 Jan; 313(4):1053-7. PubMed ID: 14706649
[TBL] [Abstract][Full Text] [Related]
7. Evidence that the transport of ricin to the cytoplasm is independent of both Rab6A and COPI.
Chen A; AbuJarour RJ; Draper RK
J Cell Sci; 2003 Sep; 116(Pt 17):3503-10. PubMed ID: 12865434
[TBL] [Abstract][Full Text] [Related]
8. Addition of an ER retention signal to the ricin A chain increases the cytotoxicity of the holotoxin.
Wales R; Chaddock JA; Roberts LM; Lord JM
Exp Cell Res; 1992 Nov; 203(1):1-4. PubMed ID: 1426032
[TBL] [Abstract][Full Text] [Related]
9. Importance of the glutamate residue of KDEL in increasing the cytotoxicity of Pseudomonas exotoxin derivatives and for increased binding to the KDEL receptor.
Kreitman RJ; Pastan I
Biochem J; 1995 Apr; 307 ( Pt 1)(Pt 1):29-37. PubMed ID: 7717988
[TBL] [Abstract][Full Text] [Related]
10. Differences in cytotoxicity of native and engineered RIPs can be used to assess their ability to reach the cytoplasm.
Svinth M; Steighardt J; Hernandez R; Suh JK; Kelly C; Day P; Lord M; Girbes T; Robertus JD
Biochem Biophys Res Commun; 1998 Aug; 249(3):637-42. PubMed ID: 9731188
[TBL] [Abstract][Full Text] [Related]
11. Introduction of a disulfide bond into ricin A chain decreases the cytotoxicity of the ricin holotoxin.
Argent RH; Roberts LM; Wales R; Robertus JD; Lord JM
J Biol Chem; 1994 Oct; 269(43):26705-10. PubMed ID: 7929403
[TBL] [Abstract][Full Text] [Related]
12. A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation.
Sokołowska I; Wälchli S; Węgrzyn G; Sandvig K; Słomińska-Wojewódzka M
Biochem J; 2011 Jun; 436(2):371-85. PubMed ID: 21388347
[TBL] [Abstract][Full Text] [Related]
13. Saporin and ricin A chain follow different intracellular routes to enter the cytosol of intoxicated cells.
Vago R; Marsden CJ; Lord JM; Ippoliti R; Flavell DJ; Flavell SU; Ceriotti A; Fabbrini MS
FEBS J; 2005 Oct; 272(19):4983-95. PubMed ID: 16176271
[TBL] [Abstract][Full Text] [Related]
14. Characterization of a ricin fusion toxin targeted to the interleukin-2 receptor.
Frankel AE; Burbage C; Fu T; Tagge E; Chandler J; Willingham M
Protein Eng; 1996 Oct; 9(10):913-9. PubMed ID: 8931131
[TBL] [Abstract][Full Text] [Related]
15. The KDEL retrieval system is exploited by Pseudomonas exotoxin A, but not by Shiga-like toxin-1, during retrograde transport from the Golgi complex to the endoplasmic reticulum.
Jackson ME; Simpson JC; Girod A; Pepperkok R; Roberts LM; Lord JM
J Cell Sci; 1999 Feb; 112 ( Pt 4)():467-75. PubMed ID: 9914159
[TBL] [Abstract][Full Text] [Related]
16. Expression of ricin A chain and ricin A chain-KDEL in Escherichia coli.
Zhan J; Chen Y; Wang K; Zheng S
Protein Expr Purif; 2004 Apr; 34(2):197-201. PubMed ID: 15003251
[TBL] [Abstract][Full Text] [Related]
17. The low lysine content of ricin A chain reduces the risk of proteolytic degradation after translocation from the endoplasmic reticulum to the cytosol.
Deeks ED; Cook JP; Day PJ; Smith DC; Roberts LM; Lord JM
Biochemistry; 2002 Mar; 41(10):3405-13. PubMed ID: 11876649
[TBL] [Abstract][Full Text] [Related]
18. Lectin-deficient ricin toxin intoxicates cells bearing the D-mannose receptor.
Frankel AE; Fu T; Burbage C; Tagge E; Harris B; Vesely J; Willingham MC
Carbohydr Res; 1997 May; 300(3):251-8. PubMed ID: 9202409
[TBL] [Abstract][Full Text] [Related]
19. IL2 fused to lectin-deficient ricin is toxic to human leukemia cells expressing the IL2 receptor.
Frankel AE; Fu T; Burbage C; Chandler J; Willingham MC; Tagge EP
Leukemia; 1997 Jan; 11(1):22-30. PubMed ID: 9001414
[TBL] [Abstract][Full Text] [Related]
20. Ricin A chain reaches the endoplasmic reticulum after endocytosis.
Liu Q; Zhan J; Chen X; Zheng S
Biochem Biophys Res Commun; 2006 May; 343(3):857-63. PubMed ID: 16564502
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
