These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

268 related articles for article (PubMed ID: 8613784)

  • 1. Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease.
    Cataldo AM; Hamilton DJ; Barnett JL; Paskevich PA; Nixon RA
    J Neurosci; 1996 Jan; 16(1):186-99. PubMed ID: 8613784
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer disease.
    Cataldo AM; Hamilton DJ; Nixon RA
    Brain Res; 1994 Mar; 640(1-2):68-80. PubMed ID: 8004466
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system.
    Cataldo AM; Barnett JL; Berman SA; Li J; Quarless S; Bursztajn S; Lippa C; Nixon RA
    Neuron; 1995 Mar; 14(3):671-80. PubMed ID: 7695914
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: neuropathologic evidence for a mechanism of increased beta-amyloidogenesis.
    Cataldo AM; Barnett JL; Pieroni C; Nixon RA
    J Neurosci; 1997 Aug; 17(16):6142-51. PubMed ID: 9236226
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a review.
    Nixon RA; Cataldo AM; Mathews PM
    Neurochem Res; 2000 Oct; 25(9-10):1161-72. PubMed ID: 11059790
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Colocalization of lysosomal hydrolase and beta-amyloid in diffuse plaques of the cerebellum and striatum in Alzheimer's disease and Down's syndrome.
    Cataldo AM; Barnett JL; Mann DM; Nixon RA
    J Neuropathol Exp Neurol; 1996 Jun; 55(6):704-15. PubMed ID: 8642396
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The lysosomal system in neurons. Involvement at multiple stages of Alzheimer's disease pathogenesis.
    Nixon RA; Cataldo AM; Paskevich PA; Hamilton DJ; Wheelock TR; Kanaley-Andrews L
    Ann N Y Acad Sci; 1992 Dec; 674():65-88. PubMed ID: 1288372
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis.
    Mathews PM; Guerra CB; Jiang Y; Grbovic OM; Kao BH; Schmidt SD; Dinakar R; Mercken M; Hille-Rehfeld A; Rohrer J; Mehta P; Cataldo AM; Nixon RA
    J Biol Chem; 2002 Feb; 277(7):5299-307. PubMed ID: 11551970
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of the endosomal/lysosomal system in amyloid-beta production and the pathophysiology of Alzheimer's disease: reexamining the spatial paradox from a lysosomal perspective.
    Pasternak SH; Callahan JW; Mahuran DJ
    J Alzheimers Dis; 2004 Feb; 6(1):53-65. PubMed ID: 15004328
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease.
    Cataldo AM; Paskevich PA; Kominami E; Nixon RA
    Proc Natl Acad Sci U S A; 1991 Dec; 88(24):10998-1002. PubMed ID: 1837142
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The endosomal-lysosomal system of neurons: new roles.
    Nixon RA; Cataldo AM
    Trends Neurosci; 1995 Nov; 18(11):489-96. PubMed ID: 8592758
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Up-regulation of the lysosomal system in experimental models of neuronal injury: implications for Alzheimer's disease.
    Adamec E; Mohan PS; Cataldo AM; Vonsattel JP; Nixon RA
    Neuroscience; 2000; 100(3):663-75. PubMed ID: 11098128
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Distribution of newly synthesized lysosomal enzymes in the endocytic pathway of normal rat kidney cells.
    Ludwig T; Griffiths G; Hoflack B
    J Cell Biol; 1991 Dec; 115(6):1561-72. PubMed ID: 1661730
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations.
    Cataldo AM; Peterhoff CM; Troncoso JC; Gomez-Isla T; Hyman BT; Nixon RA
    Am J Pathol; 2000 Jul; 157(1):277-86. PubMed ID: 10880397
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Endolyn-78, a membrane glycoprotein present in morphologically diverse components of the endosomal and lysosomal compartments: implications for lysosome biogenesis.
    Croze E; Ivanov IE; Kreibich G; Adesnik M; Sabatini DD; Rosenfeld MG
    J Cell Biol; 1989 May; 108(5):1597-613. PubMed ID: 2654137
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cellular distribution of insulin-like growth factor-II/mannose-6-phosphate receptor in normal human brain and its alteration in Alzheimer's disease pathology.
    Kar S; Poirier J; Guevara J; Dea D; Hawkes C; Robitaille Y; Quirion R
    Neurobiol Aging; 2006 Feb; 27(2):199-210. PubMed ID: 16399207
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Degenerative changes in epinephrine tonic vasomotor neurons in Alzheimer's disease.
    Burke WJ; Galvin NJ; Chung HD; Stoff SA; Gillespie KN; Cataldo AM; Nixon RA
    Brain Res; 1994 Oct; 661(1-2):35-42. PubMed ID: 7834382
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Abeta1-42 pathogenesis.
    Yang AJ; Chandswangbhuvana D; Margol L; Glabe CG
    J Neurosci Res; 1998 Jun; 52(6):691-8. PubMed ID: 9669318
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting the role of the endosome in the pathophysiology of Alzheimer's disease: a strategy for treatment.
    Tate BA; Mathews PM
    Sci Aging Knowledge Environ; 2006 Jun; 2006(10):re2. PubMed ID: 16807486
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased expression of cathepsins E and D in neurons of the aged rat brain and their colocalization with lipofuscin and carboxy-terminal fragments of Alzheimer amyloid precursor protein.
    Nakanishi H; Amano T; Sastradipura DF; Yoshimine Y; Tsukuba T; Tanabe K; Hirotsu I; Ohono T; Yamamoto K
    J Neurochem; 1997 Feb; 68(2):739-49. PubMed ID: 9003065
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.