BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 8617758)

  • 1. Human immunodeficiency virus reverse transcriptase. Functional mutants obtained by random mutagenesis coupled with genetic selection in Escherichia coli.
    Kim B; Hathaway TR; Loeb LA
    J Biol Chem; 1996 Mar; 271(9):4872-8. PubMed ID: 8617758
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enzymatic properties of two mutants of reverse transcriptase of human immunodeficiency virus type 1 (tyrosine 181-->isoleucine and tyrosine 188-->leucine), resistant to nonnucleoside inhibitors.
    Loya S; Bakhanashvili M; Tal R; Hughes SH; Boyer PL; Hizi A
    AIDS Res Hum Retroviruses; 1994 Aug; 10(8):939-46. PubMed ID: 7529032
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates.
    Ueno T; Shirasaka T; Mitsuya H
    J Biol Chem; 1995 Oct; 270(40):23605-11. PubMed ID: 7559526
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interactions of the HIV-1 reverse transcriptase 'AZT-resistant' mutant with substrates and AZT-TP.
    Pokholok DK; Gudima SO; Yesipov DS; Dobrynin VN; Rechinsky VO; Kochetkov SN
    FEBS Lett; 1993 Jul; 325(3):237-41. PubMed ID: 7686510
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Studies of the resistance of the human immunodeficiency virus to azidothymidine. I. Kinetic studies of the interaction between reverse transcriptase and a series of its mutant forms with substrates and azidothymidine-5'-trisphosphate].
    Pokholok DK; Gudima SO; Esipov DS; Dobrynin VN; Memelova LV; Rechinskiĭ VO; Kochetkov SN
    Biokhimiia; 1994 May; 59(5):739-47. PubMed ID: 7519060
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sensitivity of HIV-1 reverse transcriptase and its mutants to inhibition by azidothymidine triphosphate.
    Carroll SS; Geib J; Olsen DB; Stahlhut M; Shafer JA; Kuo LC
    Biochemistry; 1994 Mar; 33(8):2113-20. PubMed ID: 7509634
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of the amino acid in the human immunodeficiency virus type 1 reverse transcriptase involved in the pyrophosphate binding of antiviral nucleoside triphosphate analogs and phosphonoformate. Implications for multiple drug resistance.
    Im GJ; Tramontano E; Gonzalez CJ; Cheng YC
    Biochem Pharmacol; 1993 Dec; 46(12):2307-13. PubMed ID: 7506027
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutational analysis of two conserved sequence motifs in HIV-1 reverse transcriptase.
    Lowe DM; Parmar V; Kemp SD; Larder BA
    FEBS Lett; 1991 May; 282(2):231-4. PubMed ID: 1709876
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genetic selection in Escherichia coli for active human immunodeficiency virus reverse transcriptase mutants.
    Kim B
    Methods; 1997 Aug; 12(4):318-24. PubMed ID: 9245612
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interaction of the reverse transcriptase of human immunodeficiency virus type 1 with DNA.
    Bakhanashvili M; Hizi A
    Biochemistry; 1994 Oct; 33(40):12222-8. PubMed ID: 7522556
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutated K65R recombinant reverse transcriptase of human immunodeficiency virus type 1 shows diminished chain termination in the presence of 2',3'-dideoxycytidine 5'-triphosphate and other drugs.
    Gu Z; Arts EJ; Parniak MA; Wainberg MA
    Proc Natl Acad Sci U S A; 1995 Mar; 92(7):2760-4. PubMed ID: 7535930
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Infectious potential of human immunodeficiency virus type 1 reverse transcriptase mutants with altered inhibitor sensitivity.
    Larder BA; Kemp SD; Purifoy DJ
    Proc Natl Acad Sci U S A; 1989 Jul; 86(13):4803-7. PubMed ID: 2472634
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A rapid phenotypic assay for detecting multiple nucleoside analogue reverse transcriptase inhibitor-resistant HIV-1 in plasma.
    Qari SH; Winters M; Vandamme AM; Merigan T; Heneine W
    Antivir Ther; 2002 Jun; 7(2):131-9. PubMed ID: 12212925
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors.
    Schneider A; Corona A; Spöring I; Jordan M; Buchholz B; Maccioni E; Di Santo R; Bodem J; Tramontano E; Wöhrl BM
    Nucleic Acids Res; 2016 Mar; 44(5):2310-22. PubMed ID: 26850643
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enhanced binding of azidothymidine-resistant human immunodeficiency virus 1 reverse transcriptase to the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer.
    Canard B; Sarfati SR; Richardson CC
    J Biol Chem; 1998 Jun; 273(23):14596-604. PubMed ID: 9603976
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutagenesis of the Glu-89 residue in human immunodeficiency virus type 1 (HIV-1) and HIV-2 reverse transcriptases: effects on nucleoside analog resistance.
    Song Q; Yang G; Goff SP; Prasad VR
    J Virol; 1992 Dec; 66(12):7568-71. PubMed ID: 1279207
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138.
    Pelemans H; Aertsen A; Van Laethem K; Vandamme AM; De Clercq E; Pérez-Pérez MJ; San-Félix A; Velázquez S; Camarasa MJ; Balzarini J
    Virology; 2001 Feb; 280(1):97-106. PubMed ID: 11162823
    [TBL] [Abstract][Full Text] [Related]  

  • 18. AZT resistance of simian foamy virus reverse transcriptase is based on the excision of AZTMP in the presence of ATP.
    Hartl MJ; Kretzschmar B; Frohn A; Nowrouzi A; Rethwilm A; Wöhrl BM
    Nucleic Acids Res; 2008 Feb; 36(3):1009-16. PubMed ID: 18096624
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro enzymatic activity of human immunodeficiency virus type 1 reverse transcriptase mutants in the highly conserved YMDD amino acid motif correlates with the infectious potential of the proviral genome.
    Wakefield JK; Jablonski SA; Morrow CD
    J Virol; 1992 Nov; 66(11):6806-12. PubMed ID: 1383571
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutations within the RNase H domain of human immunodeficiency virus type 1 reverse transcriptase abolish virus infectivity.
    Tisdale M; Schulze T; Larder BA; Moelling K
    J Gen Virol; 1991 Jan; 72 ( Pt 1)():59-66. PubMed ID: 1703563
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.