These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 862130)

  • 21. Modification of benzo(a)pyrene metabolism in hepatic microsomes from untreated and induced rats by imidazole derivatives which inhibit monooxygenase activity and enhance epoxide hydrolase activity.
    James MO; Little PJ
    Drug Metab Dispos; 1983; 11(4):350-4. PubMed ID: 6137342
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Vitamin K epoxide reductase activity in the metabolism of epoxides.
    Liptay-Reuter I; Dose K; Guenthner T; Wörner W; Oesch F
    Biochem Pharmacol; 1985 Aug; 34(15):2617-20. PubMed ID: 4015704
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Age-related changes in benzo(a)pyrene metabolism and epoxide-metabolizing enzyme activities in rat skin.
    Mukhtar H; Bickers DR
    Drug Metab Dispos; 1983; 11(6):562-7. PubMed ID: 6140140
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Fate of epoxides.
    Oesch F
    Adv Exp Med Biol; 1981; 136 Pt A():39-52. PubMed ID: 7046377
    [No Abstract]   [Full Text] [Related]  

  • 25. Tumorigenicity studies with diol-epoxides of benzo(a)pyrene which indicate that (+/-)-trans-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene is an ultimate carcinogen in newborn mice.
    Kapitulnik J; Wislocki PG; Levin W; Yagi H; Jerina DM; Conney AH
    Cancer Res; 1978 Feb; 38(2):354-8. PubMed ID: 620406
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Stereo-selectivity and regio-selectivity in the metabolism of 7,8-dihydrobenzo[a]pyrene by cytochrome P450, epoxide hydrolase and hepatic microsomes from 3-methylcholanthrene-treated rats.
    Adams JD; Yagi H; Levin W; Jerina DM
    Chem Biol Interact; 1995 Mar; 95(1-2):57-77. PubMed ID: 7697754
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A benzo[alpha]pyrene-7,8-dihydrodiol-9,10-epoxide is the major metabolite involved in the binding of benzo[alpha]pyrene to DNA in isolated viable rat hepatocytes.
    Ashurst SW; Cohen GM
    Chem Biol Interact; 1980 Jan; 29(1):117-27. PubMed ID: 7356534
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The direct spectrophotometric observation of benzo(a)pyrene phenol formation by liver microsomes.
    Prough RA; Patrizi VW; Estabrook RW
    Cancer Res; 1976 Dec; 36(12):4439-43. PubMed ID: 1000493
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Relationship between benzo(a)pyrene-induced DNA base modification and frequency of reverse mutations in mutant strains of Salmonella typhimurium.
    Fahl WE; Scarpelli DG; Gill K
    Cancer Res; 1981 Sep; 41(9 Pt 1):3400-6. PubMed ID: 6266655
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Metabolic activation of benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide to protein-binding products and the inhibitory effect of glutathione and cysteine.
    Jernström B; Dock L; Martinez M
    Carcinogenesis; 1984 Feb; 5(2):199-204. PubMed ID: 6421502
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Metabolism of trans-9,10-dihydroxy-9,10-dihydrobenzo[a]pyrene occurs primarily by arylhydroxylation rather than formation of a diol epoxide.
    Thakker DR; Yagi H; Lehr RE; Levin W; Buening M; Lu AY; Chang RL; Wood AW; Conney AH; Jerina DM
    Mol Pharmacol; 1978 May; 14(3):502-13. PubMed ID: 661815
    [No Abstract]   [Full Text] [Related]  

  • 32. Stereoselective formations of K-region and non-K-region epoxides in the metabolism of chrysene by rat liver microsomal cytochrome P-450 isozymes.
    Yang SK; Bao ZP
    Mol Pharmacol; 1987 Jul; 32(1):73-80. PubMed ID: 3037304
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis of fjord region tetraols and their use in hepatic biotransformation studies of dihydrodiols of benzo[c]chrysene, benzo[g]chrysene and dibenzo[a,l]pyrene.
    Luch A; Platt KL; Seidel A
    Carcinogenesis; 1998 Apr; 19(4):639-48. PubMed ID: 9600349
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Microsomal metabolism on benzo(a)pyrene. Multiple effects of epoxide hydrase inhibitors.
    Fahl WE; Nesnow S; Jefcoate CR
    Arch Biochem Biophys; 1977 Jun; 181(2):649-64. PubMed ID: 900937
    [No Abstract]   [Full Text] [Related]  

  • 35. Inhibition of benzo(a)pyrene and benzo(a)pyrene 7,8-dihydrodiol metabolism by benzo(a)pyrene quinones.
    Shen AL; Fahl WE; Wrighton SA; Jefcoate CR
    Cancer Res; 1979 Oct; 39(10):4123-9. PubMed ID: 113086
    [No Abstract]   [Full Text] [Related]  

  • 36. Metabolism of benzo[a]pyrene. Effect of 3-methylcholanthrene pretreatment on metabolism by microsomes from lungs of genetically "responsive" and "nonresponsive" mice.
    Seifried HE; Birkett DJ; Levin W; Lu AY; Conney AH; Jerina DM
    Arch Biochem Biophys; 1977 Jan; 178(1):256-63. PubMed ID: 836034
    [No Abstract]   [Full Text] [Related]  

  • 37. Prediction of pulmonary benzo(a)pyrene 4,5-oxide clearance: a pharmacokinetic analysis of epoxide-metabolizing enzymes in rabbit lung.
    Smith BR; Bend JR
    J Pharmacol Exp Ther; 1980 Sep; 214(3):478-82. PubMed ID: 7190605
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Stereoselective metabolism of 8- and 9-fluorobenzo[a]pyrene by rat liver microsomes: absolute configurations of trans-dihydrodiol metabolites.
    Chou MW; Fu PP
    J Toxicol Environ Health; 1984; 14(2-3):211-23. PubMed ID: 6502733
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structural requirements for the metabolic activation of benzo[a]pyrene to mutagenic products: effects of modifications in the 4,5-, 7,8-, and 9,10-positions.
    Wood AW; Levin W; Lu AY; Ryan D; West SB; Yagi H; Mah HD; Jerina DM; Conney AH
    Mol Pharmacol; 1977 Nov; 13(6):1116-25. PubMed ID: 339055
    [No Abstract]   [Full Text] [Related]  

  • 40. An enantiomeric interaction in the metabolism and tumorigenicity of (+)- and (-)-benzo[a]pyrene 7,8-oxide.
    Levin W; Buening MK; Wood AW; Chang RL; Kedzierski B; Thakker DR; Boyd DR; Gadaginamath GS; Armstrong RN; Yagi H; Karle JM; Slaga TJ; Jerina DM; Conney AH
    J Biol Chem; 1980 Oct; 255(19):9067-74. PubMed ID: 7410412
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.