BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 8621520)

  • 1. Structure-function analysis of human alpha1,3-fucosyltransferase. Amino acids involved in acceptor substrate specificity.
    Xu Z; Vo L; Macher BA
    J Biol Chem; 1996 Apr; 271(15):8818-23. PubMed ID: 8621520
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human alpha1,3/4-fucosyltransferases. I. Identification of amino acids involved in acceptor substrate binding by site-directed mutagenesis.
    Nguyen AT; Holmes EH; Whitaker JM; Ho S; Shetterly S; Macher BA
    J Biol Chem; 1998 Sep; 273(39):25244-9. PubMed ID: 9737988
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human alpha1,3/4-fucosyltransferases. II. A single amino acid at the COOH terminus of FucT III and V alters their kinetic properties.
    Vo L; Lee S; Marcinko MC; Holmes EH; Macher BA
    J Biol Chem; 1998 Sep; 273(39):25250-5. PubMed ID: 9737989
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human alpha1,3/4-fucosyltransferases. III. A Lys/Arg residue located within the alpha1,3-FucT motif is required for activity but not substrate binding.
    Sherwood AL; Nguyen AT; Whitaker JM; Macher BA; Stroud MR; Holmes EH
    J Biol Chem; 1998 Sep; 273(39):25256-60. PubMed ID: 9737990
    [TBL] [Abstract][Full Text] [Related]  

  • 5. C-terminal amino acids of Helicobacter pylori alpha1,3/4 fucosyltransferases determine type I and type II transfer.
    Ma B; Wang G; Palcic MM; Hazes B; Taylor DE
    J Biol Chem; 2003 Jun; 278(24):21893-900. PubMed ID: 12676935
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A single aromatic amino acid at the carboxyl terminus of Helicobacter pylori {alpha}1,3/4 fucosyltransferase determines substrate specificity.
    Ma B; Lau LH; Palcic MM; Hazes B; Taylor DE
    J Biol Chem; 2005 Nov; 280(44):36848-56. PubMed ID: 16150700
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Analysis of the expression and enzymatic properties of alpha1-->3fucosyltransferase from human lung carcinoma NCI-H69 and PC9 cells.
    Sherwood AL; Holmes EH
    Glycobiology; 1999 Jul; 9(7):637-43. PubMed ID: 10362832
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Site-specific fucosylation of sialylated polylactosamines by alpha1,3/4-fucosyltransferases-V and -VI Is defined by amino acids near the N terminus of the catalytic domain.
    Shetterly S; Jost F; Watson SR; Knegtel R; Macher BA; Holmes EH
    J Biol Chem; 2007 Aug; 282(34):24882-92. PubMed ID: 17604274
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-function analysis of human alpha 1-->3fucosyltransferases. A GDP-fucose-protected, N-ethylmaleimide-sensitive site in FucT-III and FucT-V corresponds to Ser178 in FucT-IV.
    Holmes EH; Xu Z; Sherwood AL; Macher BA
    J Biol Chem; 1995 Apr; 270(14):8145-51. PubMed ID: 7713918
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of an alpha3-fucosyltransferase and a novel alpha2-fucosyltransferase activity in cercariae of the schistosome Trichobilharzia ocellata: biosynthesis of the Fucalpha1-->2Fucalpha1-->3[Gal(NAc)beta1-->4]GlcNAc sequence.
    Hokke CH; Neeleman AP; Koeleman CA; van den Eijnden DH
    Glycobiology; 1998 Apr; 8(4):393-406. PubMed ID: 9499387
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An amino acid region at the N-terminus of rat hepatoma alpha1-->2 fucosyltransferase modulates enzyme activity and interaction with lipids: strong preference for glycosphingolipids containing terminal Galbeta1-->3GalNAc-structures.
    Sherwood AL; Stroud MR; Levery SB; Holmes EH
    Biochemistry; 2001 May; 40(19):5708-19. PubMed ID: 11341836
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro alpha1-3 or alpha1-4 fucosylation of type I and II oligosaccharides with secreted forms of recombinant human fucosyltransferases III and VI.
    Nimtz M; Grabenhorst E; Gambert U; Costa J; Wray V; Morr M; Thiem J; Conradt HS
    Glycoconj J; 1998 Sep; 15(9):873-83. PubMed ID: 10052591
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human alpha 1,3/4 fucosyltransferases. Characterization of highly conserved cysteine residues and N-linked glycosylation sites.
    Holmes EH; Yen TY; Thomas S; Joshi R; Nguyen A; Long T; Gallet F; Maftah A; Julien R; Macher BA
    J Biol Chem; 2000 Aug; 275(32):24237-45. PubMed ID: 10816554
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A GDP-fucose-protected, pyridoxal-5'-Phosphate/NaBH(4)-sensitive lys residue common to human alpha1-->3Fucosyltransferases corresponds to Lys(300) in FucT-IV.
    Sherwood AL; Davis WC; Ho S; Macher BA; Stroud MR; Upchurch DA; Holmes EH
    Biochem Biophys Res Commun; 2000 Jul; 273(3):870-6. PubMed ID: 10891339
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutation of amino acids in the alpha 1,3-fucosyltransferase motif affects enzyme activity and Km for donor and acceptor substrates.
    Jost F; de Vries T; Knegtel RM; Macher BA
    Glycobiology; 2005 Feb; 15(2):165-75. PubMed ID: 15456734
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A single amino acid in the hypervariable stem domain of vertebrate alpha1,3/1,4-fucosyltransferases determines the type 1/type 2 transfer. Characterization of acceptor substrate specificity of the lewis enzyme by site-directed mutagenesis.
    Dupuy F; Petit JM; Mollicone R; Oriol R; Julien R; Maftah A
    J Biol Chem; 1999 Apr; 274(18):12257-62. PubMed ID: 10212193
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A highly conserved His-His motif present in alpha1-->3/4fucosyltransferases is required for optimal activity and functions in acceptor binding.
    Sherwood AL; Upchurch DA; Stroud MR; Davis WC; Holmes EH
    Glycobiology; 2002 Oct; 12(10):599-606. PubMed ID: 12244072
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The cloning and expression of a human alpha-1,3 fucosyltransferase capable of forming the E-selectin ligand.
    Koszdin KL; Bowen BR
    Biochem Biophys Res Commun; 1992 Aug; 187(1):152-7. PubMed ID: 1520296
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Plant members of the alpha1-->3/4-fucosyltransferase gene family encode an alpha1-->4-fucosyltransferase, potentially involved in Lewis(a) biosynthesis, and two core alpha1-->3-fucosyltransferases.
    Bakker H; Schijlen E; de Vries T; Schiphorst WE; Jordi W; Lommen A; Bosch D; van Die I
    FEBS Lett; 2001 Nov; 507(3):307-12. PubMed ID: 11696361
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Production of soluble human alpha3-fucosyltransferase (FucT VII) by membrane targeting and in vivo proteolysis.
    de Vries T; Storm J; Rotteveel F; Verdonk G; van Duin M; van den Eijnden DH; Joziasse DH; Bunschoten H
    Glycobiology; 2001 Sep; 11(9):711-7. PubMed ID: 11555615
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.