BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 8621522)

  • 21. The non-DNA-binding heterooligomeric form of mammalian steroid hormone receptors contains a hsp90-bound 59-kilodalton protein.
    Renoir JM; Radanyi C; Faber LE; Baulieu EE
    J Biol Chem; 1990 Jun; 265(18):10740-5. PubMed ID: 2355020
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Direct stoichiometric evidence that the untransformed Mr 300,000, 9S, glucocorticoid receptor is a core unit derived from a larger heteromeric complex.
    Bresnick EH; Dalman FC; Pratt WB
    Biochemistry; 1990 Jan; 29(2):520-7. PubMed ID: 2405907
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Differential effects of the hsp70-binding protein BAG-1 on glucocorticoid receptor folding by the hsp90-based chaperone machinery.
    Kanelakis KC; Morishima Y; Dittmar KD; Galigniana MD; Takayama S; Reed JC; Pratt WB
    J Biol Chem; 1999 Nov; 274(48):34134-40. PubMed ID: 10567384
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Inhibition of heat shock transcription factor by GR.
    Wadekar SA; Li D; Periyasamy S; Sánchez ER
    Mol Endocrinol; 2001 Aug; 15(8):1396-410. PubMed ID: 11463862
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Evidence that the hormone-binding domain of the mouse glucocorticoid receptor directly represses DNA binding activity in a major portion of receptors that are "misfolded" after removal of hsp90.
    Hutchison KA; Czar MJ; Pratt WB
    J Biol Chem; 1992 Feb; 267(5):3190-5. PubMed ID: 1737773
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Unliganded and hormone-bound glucocorticoid receptors interact with distinct hydrophobic sites in the Hsp90 C-terminal domain.
    Fang L; Ricketson D; Getubig L; Darimont B
    Proc Natl Acad Sci U S A; 2006 Dec; 103(49):18487-92. PubMed ID: 17130446
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Stabilization in vitro of the untransformed glucocorticoid receptor complex of S49 lymphocytes by the immunophilin ligand FK506.
    Ning YM; Sanchez ER
    J Steroid Biochem Mol Biol; 1995 Feb; 52(2):187-94. PubMed ID: 7532989
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Evidence that 5 S intermediate state in glucocorticoid receptor transformation contains hsp90 in addition to the steroid-binding protein.
    Ben-Or S
    J Steroid Biochem; 1989 Nov; 33(5):899-906. PubMed ID: 2689793
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Modulation of the Hsp90 chaperone cycle by a stringent client protein.
    Lorenz OR; Freiburger L; Rutz DA; Krause M; Zierer BK; Alvira S; Cuéllar J; Valpuesta JM; Madl T; Sattler M; Buchner J
    Mol Cell; 2014 Mar; 53(6):941-53. PubMed ID: 24613341
    [TBL] [Abstract][Full Text] [Related]  

  • 30. In vivo evidence for the generation of a glucocorticoid receptor-heat shock protein-90 complex incapable of binding hormone by the calmodulin antagonist phenoxybenzamine.
    Ning YM; Sánchez ER
    Mol Endocrinol; 1996 Jan; 10(1):14-23. PubMed ID: 8838141
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells.
    Whitesell L; Cook P
    Mol Endocrinol; 1996 Jun; 10(6):705-12. PubMed ID: 8776730
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Reconstitution of the steroid receptor.hsp90 heterocomplex assembly system of rabbit reticulocyte lysate.
    Dittmar KD; Hutchison KA; Owens-Grillo JK; Pratt WB
    J Biol Chem; 1996 May; 271(22):12833-9. PubMed ID: 8662785
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Glucocorticoid receptor thiols and steroid-binding activity.
    Simons SS; Pratt WB
    Methods Enzymol; 1995; 251():406-22. PubMed ID: 7651222
    [No Abstract]   [Full Text] [Related]  

  • 34. The seven amino acids (547-553) of rat glucocorticoid receptor required for steroid and hsp90 binding contain a functionally independent LXXLL motif that is critical for steroid binding.
    Giannoukos G; Silverstein AM; Pratt WB; Simons SS
    J Biol Chem; 1999 Dec; 274(51):36527-36. PubMed ID: 10593951
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The Hsp organizer protein hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone system.
    Morishima Y; Kanelakis KC; Silverstein AM; Dittmar KD; Estrada L; Pratt WB
    J Biol Chem; 2000 Mar; 275(10):6894-900. PubMed ID: 10702249
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Stepwise assembly of a glucocorticoid receptor.hsp90 heterocomplex resolves two sequential ATP-dependent events involving first hsp70 and then hsp90 in opening of the steroid binding pocket.
    Morishima Y; Murphy PJ; Li DP; Sanchez ER; Pratt WB
    J Biol Chem; 2000 Jun; 275(24):18054-60. PubMed ID: 10764743
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Conformational dynamics and molecular recognition: backbone dynamics of the estrogen receptor DNA-binding domain.
    Wikström A; Berglund H; Hambraeus C; van den Berg S; Härd T
    J Mol Biol; 1999 Jun; 289(4):963-79. PubMed ID: 10369775
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Localization of the 90-kDa heat shock protein-binding site within the hormone-binding domain of the glucocorticoid receptor by peptide competition.
    Dalman FC; Scherrer LC; Taylor LP; Akil H; Pratt WB
    J Biol Chem; 1991 Feb; 266(6):3482-90. PubMed ID: 1995612
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A metal-linked gapped zipper model is proposed for the hsp90-glucocorticoid receptor interaction.
    Schwartz JA; Mizukami H; Skafar DF
    FEBS Lett; 1993 Jan; 315(2):109-13. PubMed ID: 8417966
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Glucocorticoid receptor conversion to high affinity nuclear binding and transcription enhancement activity in Chinese hamster ovary cells subjected to heat and chemical stress.
    Shen P; Xie ZJ; Li H; Sánchez ER
    J Steroid Biochem Mol Biol; 1993 Dec; 47(1-6):55-64. PubMed ID: 8274442
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.