These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 8626470)

  • 1. Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo.
    Meigs TE; Roseman DS; Simoni RD
    J Biol Chem; 1996 Apr; 271(14):7916-22. PubMed ID: 8626470
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver.
    Keller RK; Zhao Z; Chambers C; Ness GC
    Arch Biochem Biophys; 1996 Apr; 328(2):324-30. PubMed ID: 8645011
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase.
    Meigs TE; Simoni RD
    Arch Biochem Biophys; 1997 Sep; 345(1):1-9. PubMed ID: 9281305
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    Correll CC; Ng L; Edwards PA
    J Biol Chem; 1994 Jul; 269(26):17390-3. PubMed ID: 8021239
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol.
    Sever N; Song BL; Yabe D; Goldstein JL; Brown MS; DeBose-Boyd RA
    J Biol Chem; 2003 Dec; 278(52):52479-90. PubMed ID: 14563840
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Distinct sterol and nonsterol signals for the regulated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase.
    Roitelman J; Simoni RD
    J Biol Chem; 1992 Dec; 267(35):25264-73. PubMed ID: 1460026
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The regulated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase requires a short-lived protein and occurs in the endoplasmic reticulum.
    Chun KT; Bar-Nun S; Simoni RD
    J Biol Chem; 1990 Dec; 265(35):22004-10. PubMed ID: 2254343
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevalonate.
    Straka MS; Panini SR
    Arch Biochem Biophys; 1995 Feb; 317(1):235-43. PubMed ID: 7872789
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mevalonic acid-dependent degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo and in vitro.
    Correll CC; Edwards PA
    J Biol Chem; 1994 Jan; 269(1):633-8. PubMed ID: 8276863
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Involvement of calcium in the mevalonate-accelerated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase.
    Roitelman J; Bar-Nun S; Inoue S; Simoni RD
    J Biol Chem; 1991 Aug; 266(24):16085-91. PubMed ID: 1908464
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in permeabilized cells.
    Meigs TE; Simoni RD
    J Biol Chem; 1992 Jul; 267(19):13547-52. PubMed ID: 1618856
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Squalene synthase-deficient mutant of Chinese hamster ovary cells.
    Bradfute DL; Silva CJ; Simoni RD
    J Biol Chem; 1992 Sep; 267(26):18308-14. PubMed ID: 1526971
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of squalene synthase but not squalene cyclase prevents mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis at a posttranscriptional level.
    Peffley DM; Gayen AK
    Arch Biochem Biophys; 1997 Jan; 337(2):251-60. PubMed ID: 9016820
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase function in alpha-toxin-perforated cells.
    Giron MD; Havel CM; Watson JA
    Proc Natl Acad Sci U S A; 1994 Jul; 91(14):6398-402. PubMed ID: 8022795
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Degradation of 3-hydroxy-3-methylglutaryl-CoA reductase in endoplasmic reticulum membranes is accelerated as a result of increased susceptibility to proteolysis.
    McGee TP; Cheng HH; Kumagai H; Omura S; Simoni RD
    J Biol Chem; 1996 Oct; 271(41):25630-8. PubMed ID: 8810339
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of peroxisomal 3-hydroxy-3-methylglutaryl coenzyme A reductase in UT2 cells: sterol biosynthesis, phosphorylation, degradation, and statin inhibition.
    Aboushadi N; Shackelford JE; Jessani N; Gentile A; Krisans SK
    Biochemistry; 2000 Jan; 39(1):237-47. PubMed ID: 10625499
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth.
    Brown MS; Goldstein JL
    J Lipid Res; 1980 Jul; 21(5):505-17. PubMed ID: 6995544
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Posttranscriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in lens epithelial cells by mevalonate-derived nonsterols.
    Cenedella RJ
    Exp Eye Res; 1997 Jul; 65(1):63-72. PubMed ID: 9237866
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HMG-CoA reductase regulation: use of structurally diverse first half-reaction squalene synthetase inhibitors to characterize the site of mevalonate-derived nonsterol regulator production in cultured IM-9 cells.
    Petras SF; Lindsey S; Harwood HJ
    J Lipid Res; 1999 Jan; 40(1):24-38. PubMed ID: 9869647
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Multivalent control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Mevalonate-derived product inhibits translation of mRNA and accelerates degradation of enzyme.
    Nakanishi M; Goldstein JL; Brown MS
    J Biol Chem; 1988 Jun; 263(18):8929-37. PubMed ID: 3379053
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.