BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 8626489)

  • 1. Direct association of STAT3 with the IFNAR-1 chain of the human type I interferon receptor.
    Yang CH; Shi W; Basu L; Murti A; Constantinescu SN; Blatt L; Croze E; Mullersman JE; Pfeffer LM
    J Biol Chem; 1996 Apr; 271(14):8057-61. PubMed ID: 8626489
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The neutralization of type I IFN biologic actions by anti-IFNAR-2 monoclonal antibodies is not entirely due to inhibition of Jak-Stat tyrosine phosphorylation.
    Novick D; Nabioullin RR; Ragsdale W; McKenna S; Weiser W; Garone L; Burkins C; Kim SH; Rubinstein M; Tepper MA; Arulanandam AR
    J Interferon Cytokine Res; 2000 Nov; 20(11):971-82. PubMed ID: 11096454
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway.
    Uddin S; Majchrzak B; Wang PC; Modi S; Khan MK; Fish EN; Platanias LC
    Biochem Biophys Res Commun; 2000 Apr; 270(1):158-62. PubMed ID: 10733921
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Catalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase.
    Rani MR; Leaman DW; Han Y; Leung S; Croze E; Fish EN; Wolfman A; Ransohoff RM
    J Biol Chem; 1999 Nov; 274(45):32507-11. PubMed ID: 10542297
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct mechanisms of STAT phosphorylation via the interferon-alpha/beta receptor. Selective inhibition of STAT3 and STAT5 by piceatannol.
    Su L; David M
    J Biol Chem; 2000 Apr; 275(17):12661-6. PubMed ID: 10777558
    [TBL] [Abstract][Full Text] [Related]  

  • 6. STAT3 activation by type I interferons is dependent on specific tyrosines located in the cytoplasmic domain of interferon receptor chain 2c. Activation of multiple STATS proceeds through the redundant usage of two tyrosine residues.
    Velichko S; Wagner TC; Turkson J; Jove R; Croze E
    J Biol Chem; 2002 Sep; 277(38):35635-41. PubMed ID: 12105218
    [TBL] [Abstract][Full Text] [Related]  

  • 7. STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFNAR1 chain of the type I interferon receptor.
    Pfeffer LM; Mullersman JE; Pfeffer SR; Murti A; Shi W; Yang CH
    Science; 1997 May; 276(5317):1418-20. PubMed ID: 9162009
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling.
    Nguyen VP; Saleh AZ; Arch AE; Yan H; Piazza F; Kim J; Krolewski JJ
    J Biol Chem; 2002 Mar; 277(12):9713-21. PubMed ID: 11786546
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential tyrosine phosphorylation of the IFNAR chain of the type I interferon receptor and of an associated surface protein in response to IFN-alpha and IFN-beta.
    Abramovich C; Shulman LM; Ratovitski E; Harroch S; Tovey M; Eid P; Revel M
    EMBO J; 1994 Dec; 13(24):5871-7. PubMed ID: 7813427
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C.
    Radaeva S; Jaruga B; Kim WH; Heller T; Liang TJ; Gao B
    Biochem J; 2004 Apr; 379(Pt 1):199-208. PubMed ID: 14690454
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of amino acid residues critical for the Src-homology 2 domain-dependent docking of Stat2 to the interferon alpha receptor.
    Krishnan K; Singh B; Krolewski JJ
    J Biol Chem; 1998 Jul; 273(31):19495-501. PubMed ID: 9677371
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation.
    Hemmann U; Gerhartz C; Heesel B; Sasse J; Kurapkat G; Grötzinger J; Wollmer A; Zhong Z; Darnell JE; Graeve L; Heinrich PC; Horn F
    J Biol Chem; 1996 May; 271(22):12999-3007. PubMed ID: 8662795
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. I. Definition of a novel phosphotyrosine motif mediating STAT1 activation.
    Gerhartz C; Heesel B; Sasse J; Hemmann U; Landgraf C; Schneider-Mergener J; Horn F; Heinrich PC; Graeve L
    J Biol Chem; 1996 May; 271(22):12991-8. PubMed ID: 8662591
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The proximal tyrosines of the cytoplasmic domain of the beta chain of the type I interferon receptor are essential for signal transducer and activator of transcription (Stat) 2 activation. Evidence that two Stat2 sites are required to reach a threshold of interferon alpha-induced Stat2 tyrosine phosphorylation that allows normal formation of interferon-stimulated gene factor 3.
    Nadeau OW; Domanski P; Usacheva A; Uddin S; Platanias LC; Pitha P; Raz R; Levy D; Majchrzak B; Fish E; Colamonici OR
    J Biol Chem; 1999 Feb; 274(7):4045-52. PubMed ID: 9933596
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-function study of the extracellular domain of the human type I interferon receptor (IFNAR)-1 subunit.
    Kumaran J; Colamonici OR; Fish EN
    J Interferon Cytokine Res; 2000 May; 20(5):479-85. PubMed ID: 10841076
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.
    Smit LS; Meyer DJ; Billestrup N; Norstedt G; Schwartz J; Carter-Su C
    Mol Endocrinol; 1996 May; 10(5):519-33. PubMed ID: 8732683
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of a novel conserved motif in the STAT family that is required for tyrosine phosphorylation.
    Gamero AM; Sakamoto S; Montenegro J; Larner AC
    J Biol Chem; 2004 Mar; 279(13):12379-85. PubMed ID: 14722125
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Luteolin sensitizes the antiproliferative effect of interferon α/β by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in cancer cells.
    Tai Z; Lin Y; He Y; Huang J; Guo J; Yang L; Zhang G; Wang F
    Cell Signal; 2014 Mar; 26(3):619-28. PubMed ID: 24333668
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evidence for glycosphingolipid modification of the type 1 IFN receptor.
    Ghislain J; Lingwood CA; Fish EN
    J Immunol; 1994 Oct; 153(8):3655-63. PubMed ID: 7930586
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bradykinin activates the Janus-activated kinase/signal transducers and activators of transcription (JAK/STAT) pathway in vascular endothelial cells: localization of JAK/STAT signalling proteins in plasmalemmal caveolae.
    Ju H; Venema VJ; Liang H; Harris MB; Zou R; Venema RC
    Biochem J; 2000 Oct; 351(Pt 1):257-64. PubMed ID: 10998369
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.