These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
259 related articles for article (PubMed ID: 8627607)
1. Nonclassical 2,4-diamino-8-deazafolate analogues as inhibitors of dihydrofolate reductases from rat liver, Pneumocystis carinii, and Toxoplasma gondii. Gangjee A; Zhu Y; Queener SF; Francom P; Broom AD J Med Chem; 1996 Apr; 39(9):1836-45. PubMed ID: 8627607 [TBL] [Abstract][Full Text] [Related]
2. 2,4-diamino-5-deaza-6-substituted pyrido[2,3-d]pyrimidine antifolates as potent and selective nonclassical inhibitors of dihydrofolate reductases. Gangjee A; Vasudevan A; Queener SF; Kisliuk RL J Med Chem; 1996 Mar; 39(7):1438-46. PubMed ID: 8691474 [TBL] [Abstract][Full Text] [Related]
3. Effect of N9-methylation and bridge atom variation on the activity of 5-substituted 2,4-diaminopyrrolo[2,3-d]pyrimidines against dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii. Gangjee A; Mavandadi F; Queener SF J Med Chem; 1997 Mar; 40(7):1173-7. PubMed ID: 9089339 [TBL] [Abstract][Full Text] [Related]
4. 6-Substituted 2,4-diaminopyrido[3,2-d]pyrimidine analogues of piritrexim as inhibitors of dihydrofolate reductase from rat liver, Pneumocystis carinii, and Toxoplasma gondii and as antitumor agents. Gangjee A; Zhu Y; Queener SF J Med Chem; 1998 Nov; 41(23):4533-41. PubMed ID: 9804692 [TBL] [Abstract][Full Text] [Related]
5. Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase inhibitors and antitumor agents: synthesis and biological activities of 2,4-diamino-5-methyl-6-[(monosubstituted anilino)methyl] pyrido[2,3-d]pyrimidines. Gangjee A; Adair O; Queener SF J Med Chem; 1999 Jul; 42(13):2447-55. PubMed ID: 10395486 [TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of 2,4-diamino-6-(arylaminomethyl)pyrido[2,3-d]pyrimidines as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase and as antiopportunistic infection and antitumor agents. Gangjee A; Adair OO; Queener SF J Med Chem; 2003 Nov; 46(23):5074-82. PubMed ID: 14584957 [TBL] [Abstract][Full Text] [Related]
7. Synthesis of 5-methyl-5-deaza nonclassical antifolates as inhibitors of dihydrofolate reductases and as potential antipneumocystis, antitoxoplasma, and antitumor agents. Gangjee A; Shi J; Queener SF; Barrows LR; Kisliuk RL J Med Chem; 1993 Oct; 36(22):3437-43. PubMed ID: 8230134 [TBL] [Abstract][Full Text] [Related]
8. Selective Pneumocystis carinii dihydrofolate reductase inhibitors: design, synthesis, and biological evaluation of new 2,4-diamino-5-substituted-furo[2,3-d]pyrimidines. Gangjee A; Guo X; Queener SF; Cody V; Galitsky N; Luft JR; Pangborn W J Med Chem; 1998 Apr; 41(8):1263-71. PubMed ID: 9548816 [TBL] [Abstract][Full Text] [Related]
9. Lipophilic antifolates as agents against opportunistic infections. 1. Agents superior to trimetrexate and piritrexim against Toxoplasma gondii and Pneumocystis carinii in in vitro evaluations. Piper JR; Johnson CA; Krauth CA; Carter RL; Hosmer CA; Queener SF; Borotz SE; Pfefferkorn ER J Med Chem; 1996 Mar; 39(6):1271-80. PubMed ID: 8632434 [TBL] [Abstract][Full Text] [Related]
10. Conformationally restricted analogues of trimethoprim: 2,6-diamino-8-substituted purines as potential dihydrofolate reductase inhibitors from Pneumocystis carinii and Toxoplasma gondii. Gangjee A; Vasudevan A; Queener SF J Med Chem; 1997 Sep; 40(19):3032-9. PubMed ID: 9301665 [TBL] [Abstract][Full Text] [Related]
11. New 2,4-diamino-5-(2',5'-substituted benzyl)pyrimidines as potential drugs against opportunistic infections of AIDS and other immune disorders. Synthesis and species-dependent antifolate activity. Rosowsky A; Forsch RA; Sibley CH; Inderlied CB; Queener SF J Med Chem; 2004 Mar; 47(6):1475-86. PubMed ID: 14998335 [TBL] [Abstract][Full Text] [Related]
12. 2,4-Diaminopyrido[3,2-d]pyrimidine inhibitors of dihydrofolate reductase from Pneumocystis carinii and Toxoplasma gondii. Rosowsky A; Forsch RA; Queener SF J Med Chem; 1995 Jul; 38(14):2615-20. PubMed ID: 7629801 [TBL] [Abstract][Full Text] [Related]
13. 2,4-Diamino-6,7-dihydro-5H-cyclopenta[d]pyrimidine analogues of trimethoprim as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase. Rosowsky A; Papoulis AT; Queener SF J Med Chem; 1998 Mar; 41(6):913-8. PubMed ID: 9526565 [TBL] [Abstract][Full Text] [Related]
14. 2,4-Diaminothieno[2,3-d]pyrimidine lipophilic antifolates as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase. Rosowsky A; Papoulis AT; Queener SF J Med Chem; 1997 Oct; 40(22):3694-9. PubMed ID: 9357537 [TBL] [Abstract][Full Text] [Related]
15. Structure-based design and synthesis of lipophilic 2,4-diamino-6-substituted quinazolines and their evaluation as inhibitors of dihydrofolate reductases and potential antitumor agents. Gangjee A; Vidwans AP; Vasudevan A; Queener SF; Kisliuk RL; Cody V; Li R; Galitsky N; Luft JR; Pangborn W J Med Chem; 1998 Aug; 41(18):3426-34. PubMed ID: 9719595 [TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological evaluation of nonclassical 2,4-diamino-5-methylpyrido[2,3-d]pyrimidines with novel side chain substituents as potential inhibitors of dihydrofolate reductases. Gangjee A; Vasudevan A; Queener SF J Med Chem; 1997 Feb; 40(4):479-85. PubMed ID: 9046338 [TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological activities of conformationally restricted, tricyclic nonclassical antifolates as inhibitors of dihydrofolate reductases. Gangjee A; Shi J; Queener SF J Med Chem; 1997 Jun; 40(12):1930-6. PubMed ID: 9191971 [TBL] [Abstract][Full Text] [Related]
18. Further studies on 2,4-diamino-5-(2',5'-disubstituted benzyl)pyrimidines as potent and selective inhibitors of dihydrofolate reductases from three major opportunistic pathogens of AIDS. Rosowsky A; Forsch RA; Queener SF J Med Chem; 2003 Apr; 46(9):1726-36. PubMed ID: 12699390 [TBL] [Abstract][Full Text] [Related]
19. Nonclassical 2,4-diamino-5-aryl-6-ethylpyrimidine antifolates: activity as inhibitors of dihydrofolate reductase from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents. Robson C; Meek MA; Grunwaldt JD; Lambert PA; Queener SF; Schmidt D; Griffin RJ J Med Chem; 1997 Sep; 40(19):3040-8. PubMed ID: 9301666 [TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological activities of tricyclic conformationally restricted tetrahydropyrido annulated furo[2,3-d]pyrimidines as inhibitors of dihydrofolate reductases. Gangjee A; Elzein E; Queener SF; McGuire JJ J Med Chem; 1998 Apr; 41(9):1409-16. PubMed ID: 9554874 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]