162 related articles for article (PubMed ID: 8627608)
1. Novel terphenyls as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents.
Li JJ; Norton MB; Reinhard EJ; Anderson GD; Gregory SA; Isakson PC; Koboldt CM; Masferrer JL; Perkins WE; Seibert K; Zhang Y; Zweifel BS; Reitz DB
J Med Chem; 1996 Apr; 39(9):1846-56. PubMed ID: 8627608
[TBL] [Abstract][Full Text] [Related]
2. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.
Riendeau D; Percival MD; Boyce S; Brideau C; Charleson S; Cromlish W; Ethier D; Evans J; Falgueyret JP; Ford-Hutchinson AW; Gordon R; Greig G; Gresser M; Guay J; Kargman S; Léger S; Mancini JA; O'Neill G; Ouellet M; Rodger IW; Thérien M; Wang Z; Webb JK; Wong E; Chan CC
Br J Pharmacol; 1997 May; 121(1):105-17. PubMed ID: 9146894
[TBL] [Abstract][Full Text] [Related]
3. ABT-963 [2-(3,4-difluoro-phenyl)-4-(3-hydroxy-3-methyl-butoxy)-5-(4-methanesulfonyl-phenyl)-2H-pyridazin-3-one], a highly potent and selective disubstituted pyridazinone cyclooxgenase-2 inhibitor.
Harris RR; Black L; Surapaneni S; Kolasa T; Majest S; Namovic MT; Grayson G; Komater V; Wilcox D; King L; Marsh K; Jarvis MF; Nuss M; Nellans H; Pruesser L; Reinhart GA; Cox B; Jacobson P; Stewart A; Coghlan M; Carter G; Bell RL
J Pharmacol Exp Ther; 2004 Dec; 311(3):904-12. PubMed ID: 15277581
[TBL] [Abstract][Full Text] [Related]
4. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4- and 1,2,4-thiadiazole series.
Song Y; Connor DT; Sercel AD; Sorenson RJ; Doubleday R; Unangst PC; Roth BD; Beylin VG; Gilbertsen RB; Chan K; Schrier DJ; Guglietta A; Bornemeier DA; Dyer RD
J Med Chem; 1999 Apr; 42(7):1161-9. PubMed ID: 10197960
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.
Song Y; Connor DT; Doubleday R; Sorenson RJ; Sercel AD; Unangst PC; Roth BD; Gilbertsen RB; Chan K; Schrier DJ; Guglietta A; Bornemeier DA; Dyer RD
J Med Chem; 1999 Apr; 42(7):1151-60. PubMed ID: 10197959
[TBL] [Abstract][Full Text] [Related]
6. Valdecoxib: assessment of cyclooxygenase-2 potency and selectivity.
Gierse JK; Zhang Y; Hood WF; Walker MC; Trigg JS; Maziasz TJ; Koboldt CM; Muhammad JL; Zweifel BS; Masferrer JL; Isakson PC; Seibert K
J Pharmacol Exp Ther; 2005 Mar; 312(3):1206-12. PubMed ID: 15494548
[TBL] [Abstract][Full Text] [Related]
7. 1,2-Diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents.
Khanna IK; Weier RM; Yu Y; Xu XD; Koszyk FJ; Collins PW; Koboldt CM; Veenhuizen AW; Perkins WE; Casler JJ; Masferrer JL; Zhang YY; Gregory SA; Seibert K; Isakson PC
J Med Chem; 1997 May; 40(11):1634-47. PubMed ID: 9171873
[TBL] [Abstract][Full Text] [Related]
8. Diarylspiro[2.4]heptenes as orally active, highly selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationships.
Huang HC; Li JJ; Garland DJ; Chamberlain TS; Reinhard EJ; Manning RE; Seibert K; Koboldt CM; Gregory SA; Anderson GD; Veenhuizen AW; Zhang Y; Perkins WE; Burton EG; Cogburn JN; Isakson PC; Reitz DB
J Med Chem; 1996 Jan; 39(1):253-66. PubMed ID: 8568815
[TBL] [Abstract][Full Text] [Related]
9. Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles.
Chan CC; Boyce S; Brideau C; Charleson S; Cromlish W; Ethier D; Evans J; Ford-Hutchinson AW; Forrest MJ; Gauthier JY; Gordon R; Gresser M; Guay J; Kargman S; Kennedy B; Leblanc Y; Leger S; Mancini J; O'Neill GP; Ouellet M; Patrick D; Percival MD; Perrier H; Prasit P; Rodger I
J Pharmacol Exp Ther; 1999 Aug; 290(2):551-60. PubMed ID: 10411562
[TBL] [Abstract][Full Text] [Related]
10. Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays.
Riendeau D; Charleson S; Cromlish W; Mancini JA; Wong E; Guay J
Can J Physiol Pharmacol; 1997 Sep; 75(9):1088-95. PubMed ID: 9365818
[TBL] [Abstract][Full Text] [Related]
11. 1,2-Diarylpyrroles as potent and selective inhibitors of cyclooxygenase-2.
Khanna IK; Weier RM; Yu Y; Collins PW; Miyashiro JM; Koboldt CM; Veenhuizen AW; Currie JL; Seibert K; Isakson PC
J Med Chem; 1997 May; 40(11):1619-33. PubMed ID: 9171872
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and biological evaluation of 6-substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors.
Praveen Rao PN; Amini M; Li H; Habeeb AG; Knaus EE
J Med Chem; 2003 Nov; 46(23):4872-82. PubMed ID: 14584938
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis, and biological evaluation of N-acetyl-2-(or 3-)carboxymethylbenzenesulfonamides as cyclooxygenase isozyme inhibitors.
Chen QH; Rao PN; Knaus EE
Bioorg Med Chem; 2005 Aug; 13(15):4694-703. PubMed ID: 15914011
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of cyclooxygenase (COX) enzymes by compounds from Daucus carota L. Seeds.
Momin RA; De Witt DL; Nair MG
Phytother Res; 2003 Sep; 17(8):976-9. PubMed ID: 13680840
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and structure-activity relationship of a new series of COX-2 selective inhibitors: 1,5-diarylimidazoles.
Almansa C; Alfón J; de Arriba AF; Cavalcanti FL; Escamilla I; Gómez LA; Miralles A; Soliva R; Bartrolí J; Carceller E; Merlos M; García-Rafanell J
J Med Chem; 2003 Jul; 46(16):3463-75. PubMed ID: 12877584
[TBL] [Abstract][Full Text] [Related]
16. Evaluation of COX-1/COX-2 selectivity and potency of a new class of COX-2 inhibitors.
Gierse J; Nickols M; Leahy K; Warner J; Zhang Y; Cortes-Burgos L; Carter J; Seibert K; Masferrer J
Eur J Pharmacol; 2008 Jun; 588(1):93-8. PubMed ID: 18457826
[TBL] [Abstract][Full Text] [Related]
17. Covalent modification of cyclooxygenase-2 (COX-2) by 2-acetoxyphenyl alkyl sulfides, a new class of selective COX-2 inactivators.
Kalgutkar AS; Kozak KR; Crews BC; Hochgesang GP; Marnett LJ
J Med Chem; 1998 Nov; 41(24):4800-18. PubMed ID: 9822550
[TBL] [Abstract][Full Text] [Related]
18. Imrecoxib: a novel and selective cyclooxygenase 2 inhibitor with anti-inflammatory effect.
Chen XH; Bai JY; Shen F; Bai AP; Guo ZR; Cheng GF
Acta Pharmacol Sin; 2004 Jul; 25(7):927-31. PubMed ID: 15210067
[TBL] [Abstract][Full Text] [Related]
19. Anti-inflammatory action of legume isoflavonoid sophoricoside through inhibition on cyclooxygenase-2 activity.
Kim BH; Chung EY; Min BK; Lee SH; Kim MK; Min KR; Kim Y
Planta Med; 2003 May; 69(5):474-6. PubMed ID: 12802736
[TBL] [Abstract][Full Text] [Related]
20. 3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)(2-pyridyl) phenyl ketone as a potent and orally active cyclooxygenase-2 selective inhibitor: synthesis and biological evaluation.
Khanapure SP; Augustyniak ME; Earl RA; Garvey DS; Letts LG; Martino AM; Murty MG; Schwalb DJ; Shumway MJ; Trocha AM; Young DV; Zemtseva IS; Janero DR
J Med Chem; 2005 Jun; 48(11):3930-4. PubMed ID: 15916445
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
