BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

67 related articles for article (PubMed ID: 8630998)

  • 1. Expression of rTS correlates with altered growth regulation of thymidylate synthase.
    Black AR; Dolnick BJ
    Cancer Res; 1996 Feb; 56(4):700-5. PubMed ID: 8630998
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Quantitation of dihydrofolate reductase and thymidylate synthase mRNAs in vivo and in vitro by polymerase chain reaction.
    Dolnick BJ; Zhang ZG; Hines JD; Rustum YM
    Oncol Res; 1992; 4(2):65-72. PubMed ID: 1596583
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alternate splicing of the rTS gene product and its overexpression in a 5-fluorouracil-resistant cell line.
    Dolnick BJ; Black AR
    Cancer Res; 1996 Jul; 56(14):3207-10. PubMed ID: 8764108
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells.
    Marverti G; Ligabue A; Paglietti G; Corona P; Piras S; Vitale G; Guerrieri D; Luciani R; Costi MP; Frassineti C; Moruzzi MS
    Eur J Pharmacol; 2009 Aug; 615(1-3):17-26. PubMed ID: 19446547
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacogenomic dissection of resistance to thymidylate synthase inhibitors.
    Wang W; Marsh S; Cassidy J; McLeod HL
    Cancer Res; 2001 Jul; 61(14):5505-10. PubMed ID: 11454699
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Recent advances in the study of rTS proteins. rTS expression during growth and in response to thymidylate synthase inhibitors in human tumor cells.
    Dolnick BJ; Lu K; Yin MB; Rustum YM
    Adv Enzyme Regul; 1997; 37():95-109. PubMed ID: 9381988
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enhancement of 5-fluorouracil sensitivity by an rTS signaling mimic in H630 colon cancer cells.
    Dolnick R; Wu Q; Angelino NJ; Stephanie LV; Chow KC; Sufrin JR; Dolnick BJ
    Cancer Res; 2005 Jul; 65(13):5917-24. PubMed ID: 15994970
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Detection and quantitation of thymidylate synthase mRNA in human colon adenocarcinoma cell line resistant to 5-fluorouracil by competitive PCR.
    Shibata J; Aiba K; Shibata H; Minowa S; Horikoshi N
    Anticancer Res; 1998; 18(3A):1457-63. PubMed ID: 9673356
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thymidylate synthase as a target for growth inhibition in methotrexate-sensitive and -resistant human head and neck cancer and leukemia cell lines.
    McGuire JJ; Magee KJ; Russell CA; Canestrari JM
    Oncol Res; 1997; 9(3):139-47. PubMed ID: 9220499
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ex vivo activity of methotrexate versus novel antifolate inhibitors of dihydrofolate reductase and thymidylate synthase against childhood leukemia cells.
    Mauritz R; Bekkenk MW; Rots MG; Pieters R; Mini E; van Zantwijk CH; Veerman AJ; Peters GJ; Jansen G
    Clin Cancer Res; 1998 Oct; 4(10):2399-410. PubMed ID: 9796971
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protection of hematopoietic stem cells from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene.
    Capiaux GM; Budak-Alpdogan T; Alpdogan O; Bornmann W; Takebe N; Banerjee D; Maley F; Bertino JR
    Cancer Gene Ther; 2004 Dec; 11(12):767-73. PubMed ID: 15359285
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of combined inhibitors of thymidylate synthase-5-fluorodeoxyuridine and quinazoline antifolates on murine leukemia cells cultured in vitro.
    Balinska M; Szablewska I; Janiszewska D; Brzezinska A; Pawelczak K
    Anticancer Res; 1997; 17(6D):4519-24. PubMed ID: 9494561
    [TBL] [Abstract][Full Text] [Related]  

  • 13. p14ARF expression increases dihydrofolate reductase degradation and paradoxically results in resistance to folate antagonists in cells with nonfunctional p53.
    Magro PG; Russo AJ; Li WW; Banerjee D; Bertino JR
    Cancer Res; 2004 Jun; 64(12):4338-45. PubMed ID: 15205349
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Retroviral coexpression of thymidylate synthase and dihydrofolate reductase confers fluoropyrimidine and antifolate resistance.
    Fantz CR; Shaw D; Moore JG; Spencer HT
    Biochem Biophys Res Commun; 1998 Feb; 243(1):6-12. PubMed ID: 9473470
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nuclear topography and expression of the BCR/ABL fusion gene and its protein level influenced by cell differentiation and RNA interference.
    Bártová E; Harnicarová A; Pacherník J; Kozubek S
    Leuk Res; 2005 Aug; 29(8):901-13. PubMed ID: 15978941
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antitumor activity of antifolate inhibitors of thymidylate and purine synthesis in human soft tissue sarcoma cell lines with intrinsic resistance to methotrexate.
    Li WW; Tong WP; Bertino JR
    Clin Cancer Res; 1995 Jun; 1(6):631-6. PubMed ID: 9816025
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Engineered resistance to camptothecin and antifolates by retroviral coexpression of tyrosyl DNA phosphodiesterase-I and thymidylate synthase.
    Nivens MC; Felder T; Galloway AH; Pena MM; Pouliot JJ; Spencer HT
    Cancer Chemother Pharmacol; 2004 Feb; 53(2):107-15. PubMed ID: 14605862
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of Grb2 and Crkl proteins results in growth inhibition of Philadelphia chromosome positive leukemic cells.
    Tari AM; Arlinghaus R; Lopez-Berestein G
    Biochem Biophys Res Commun; 1997 Jun; 235(2):383-8. PubMed ID: 9199202
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thymidylate synthase gene amplification in fluorodeoxyuridine-resistant mouse cell lines.
    Jenh CH; Geyer PK; Baskin F; Johnson LF
    Mol Pharmacol; 1985 Jul; 28(1):80-5. PubMed ID: 2991733
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer.
    Nita ME; Tominaga O; Nagawa H; Tsuruo T; Muto T
    Hepatogastroenterology; 1998; 45(24):2117-22. PubMed ID: 9951876
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.