283 related articles for article (PubMed ID: 8632433)
1. Potent inhibitors of acyl-CoA:cholesterol acyltransferase. 2. Structure-activity relationships of novel N-(2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)amides.
Kataoka K; Shiota T; Takeyasu T; Minoshima T; Watanabe K; Tanaka H; Mochizuki T; Taneda K; Ota M; Tanabe H; Yamaguchi H
J Med Chem; 1996 Mar; 39(6):1262-70. PubMed ID: 8632433
[TBL] [Abstract][Full Text] [Related]
2. Potent inhibitors of acyl-CoA:cholesterol acyltransferase. Structure-activity relationships of novel N-(4-oxochroman-8-yl)amides.
Kataoka K; Shiota T; Takeyasu T; Mochizuki T; Taneda K; Ota M; Tanabe H; Yamaguchi H
J Med Chem; 1995 Aug; 38(16):3174-86. PubMed ID: 7636880
[TBL] [Abstract][Full Text] [Related]
3. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. synthesis and pharmacological activity of (+/-)-2-dodecyl-alpha-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-5- acetamide and structurally related tetrazole amide derivatives.
O'Brien PM; Sliskovic DR; Picard JA; Lee HT; Purchase CF; Roth BD; White AD; Anderson M; Mueller SB; Bocan T; Bousley R; Hamelehle KL; Homan R; Lee P; Krause BR; Reindel JF; Stanfield RL; Turluck D
J Med Chem; 1996 Jun; 39(12):2354-66. PubMed ID: 8691430
[TBL] [Abstract][Full Text] [Related]
4. Heterocyclic amides: inhibitors of acyl-CoA:cholesterol O-acyl transferase with hypocholesterolemic activity in several species and antiatherosclerotic activity in the rabbit.
White AD; Purchase CF; Picard JA; Anderson MK; Mueller SB; Bocan TM; Bousley RF; Hamelehle KL; Krause BR; Lee P; Stanfield RL; Reindel JF
J Med Chem; 1996 Sep; 39(20):3908-19. PubMed ID: 8831757
[TBL] [Abstract][Full Text] [Related]
5. Acyl-CoA:Cholesterol O-acyltransferase (ACAT) inhibitors. 2. 2-(1,3-Dioxan-2-yl)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT.
Astles PC; Ashton MJ; Bridge AW; Harris NV; Hart TW; Parrott DP; Porter B; Riddell D; Smith C; Williams RJ
J Med Chem; 1996 Mar; 39(7):1423-32. PubMed ID: 8691472
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and structure-activity relationship studies on a novel series of naphthylidinoylureas as inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT).
Ohnuma S; Muraoka M; Ioriya K; Ohashi N
Bioorg Med Chem Lett; 2004 Mar; 14(5):1309-11. PubMed ID: 14980688
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of novel 4,5-diphenylthiazole derivatives as potential acyl-CoA:cholesterol O-acyltransferase inhibitors.
Romeo G; Salerno L; Milla P; Siracusa M; Cattel L; Russo F
Pharmazie; 1999 Jan; 54(1):19-23. PubMed ID: 9987793
[TBL] [Abstract][Full Text] [Related]
8. Relationships between lipophilicity and biological activities in a series of indoline-based anti-oxidative acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors.
Takahashi K; Kunishiro K; Kasai M; Miike T; Kurahashi K; Shirahase H
Arzneimittelforschung; 2008; 58(12):666-72. PubMed ID: 19202739
[TBL] [Abstract][Full Text] [Related]
9. Inhibitors of acyl CoA:cholesterol acyltransferase.
Vaccaro W; Amore C; Berger J; Burrier R; Clader J; Davis H; Domalski M; Fevig T; Salisbury B; Sher R
J Med Chem; 1996 Apr; 39(8):1704-19. PubMed ID: 8648610
[TBL] [Abstract][Full Text] [Related]
10. Hypolipidemic and antioxidant activity of the novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor KY-455 in rabbits and hamsters.
Nakamura S; Kamiya S; Shirahase H; Kanda M; Yoshimi A; Tarumi T; Kurahashi K
Arzneimittelforschung; 2004; 54(2):102-8. PubMed ID: 15038459
[TBL] [Abstract][Full Text] [Related]
11. alpha-Substituted malonester amides: tools to define the relationship between ACAT inhibition and adrenal toxicity.
Sliskovic DR; Picard JA; O'Brien PM; Liao P; Roark WH; Roth BD; Anderson MA; Mueller SB; Bocan TM; Bousley RF; Hamelehle KL; Homan R; Reindel JF; Stanfield RL; Turluck D; Krause BR
J Med Chem; 1998 Feb; 41(5):682-90. PubMed ID: 9513596
[TBL] [Abstract][Full Text] [Related]
12. Chemical modification and structure-activity relationships of pyripyropenes. 3. Synthetic conversion of pyridine-pyrone moiety.
Obata R; Sunazuka T; Tian Z; Tomoda H; Harigaya Y; Omura S
J Antibiot (Tokyo); 1997 Mar; 50(3):229-36. PubMed ID: 9127194
[TBL] [Abstract][Full Text] [Related]
13. Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity.
Devadas B; Freeman SK; Zupec ME; Lu HF; Nagarajan SR; Kishore NS; Lodge JK; Kuneman DW; McWherter CA; Vinjamoori DV; Getman DP; Gordon JI; Sikorski JA
J Med Chem; 1997 Aug; 40(16):2609-25. PubMed ID: 9258368
[TBL] [Abstract][Full Text] [Related]
14. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 2. Identification and structure-activity relationships of a novel series of N-alkyl-N-(heteroaryl-substituted benzyl)-N'-arylureas.
Tanaka A; Terasawa T; Hagihara H; Sakuma Y; Ishibe N; Sawada M; Takasugi H; Tanaka H
J Med Chem; 1998 Jun; 41(13):2390-410. PubMed ID: 9632372
[TBL] [Abstract][Full Text] [Related]
15. Bioavailable acyl-CoA: cholesterol acyltransferase inhibitor with anti-peroxidative activity: synthesis and biological activity of novel indolinyl amide and urea derivatives.
Kamiya S; Shirahase H; Yoshimi A; Nakamura S; Kanda M; Matsui H; Kasai M; Takahashi K; Kurahashi K
Chem Pharm Bull (Tokyo); 2000 Jun; 48(6):817-27. PubMed ID: 10866142
[TBL] [Abstract][Full Text] [Related]
16. Novel indoline-based acyl-CoA: cholesterol acyltransferase inhibitor: Effects of introducing a methanesulfonamide group on physicochemical properties and biological activities.
Shoji Y; Takahashi K; Ohta M; Kasai M; Kunishiro K; Kanda M; Yogai S; Takeuchi Y; Shirahase H
Bioorg Med Chem; 2009 Aug; 17(16):6020-31. PubMed ID: 19608421
[TBL] [Abstract][Full Text] [Related]
17. Acyl-CoA: cholesterol acyltransferase inhibitory activities of fatty acid amides isolated from Mylabris phalerate Pallas.
Xu MZ; Lee WS; Kim MJ; Park DS; Yu H; Tian GR; Jeong TS; Park HY
Bioorg Med Chem Lett; 2004 Aug; 14(16):4277-80. PubMed ID: 15261286
[TBL] [Abstract][Full Text] [Related]
18. Stimulation of cholesterol release from rabbit foam cells by the action of a new inhibitor for acyl CoA:cholesterol acyltransferase (ACAT), HL-004.
Ishii I; Yokoyama N; Yanagimachi M; Ashikawa N; Hata M; Murakami S; Asami Y; Morisaki N; Saito Y; Ohmori S; Kitada M
J Pharmacol Exp Ther; 1998 Oct; 287(1):115-21. PubMed ID: 9765329
[TBL] [Abstract][Full Text] [Related]
19. Cholesterol-lowering effects of NTE-122, a novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, on cholesterol diet-fed rats and rabbits.
Azuma Y; Kawasaki T; Ikemoto K; Obata K; Ohno K; Sajiki N; Yamada T; Yamasaki M; Nobuhara Y
Jpn J Pharmacol; 1998 Nov; 78(3):355-64. PubMed ID: 9869270
[TBL] [Abstract][Full Text] [Related]
20. Inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT). 2. Modification of fatty acid anilide ACAT inhibitors: bioisosteric replacement of the amide bond.
Roark WH; Roth BD; Holmes A; Trivedi BK; Kieft KA; Essenburg AD; Krause BR; Stanfield RL
J Med Chem; 1993 May; 36(11):1662-8. PubMed ID: 8496932
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
