168 related articles for article (PubMed ID: 8636266)
1. Functional characteristics of three new germline mutations of the thyrotropin receptor gene causing autosomal dominant toxic thyroid hyperplasia.
Tonacchera M; Van Sande J; Cetani F; Swillens S; Schvartz C; Winiszewski P; Portmann L; Dumont JE; Vassart G; Parma J
J Clin Endocrinol Metab; 1996 Feb; 81(2):547-54. PubMed ID: 8636266
[TBL] [Abstract][Full Text] [Related]
2. Diversity and prevalence of somatic mutations in the thyrotropin receptor and Gs alpha genes as a cause of toxic thyroid adenomas.
Parma J; Duprez L; Van Sande J; Hermans J; Rocmans P; Van Vliet G; Costagliola S; Rodien P; Dumont JE; Vassart G
J Clin Endocrinol Metab; 1997 Aug; 82(8):2695-701. PubMed ID: 9253356
[TBL] [Abstract][Full Text] [Related]
3. Identification and functional characterization of two novel activating thyrotropin receptor mutants in toxic thyroid follicular adenomas.
Castro I; Lima L; Seoane R; Lado-Abeal J
Thyroid; 2009 Jun; 19(6):645-9. PubMed ID: 19499991
[TBL] [Abstract][Full Text] [Related]
4. Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3',5'-monophosphate and inositol phosphate-Ca2+ cascades.
Parma J; Van Sande J; Swillens S; Tonacchera M; Dumont J; Vassart G
Mol Endocrinol; 1995 Jun; 9(6):725-33. PubMed ID: 8592518
[TBL] [Abstract][Full Text] [Related]
5. Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3',5'-cyclic adenosine monophosphate signal generation.
Kosugi S; Okajima F; Ban T; Hidaka A; Shenker A; Kohn LD
Mol Endocrinol; 1993 Aug; 7(8):1009-20. PubMed ID: 7901757
[TBL] [Abstract][Full Text] [Related]
6. A familial thyrotropin (TSH) receptor mutation provides in vivo evidence that the inositol phosphates/Ca2+ cascade mediates TSH action on thyroid hormone synthesis.
Grasberger H; Van Sande J; Hag-Dahood Mahameed A; Tenenbaum-Rakover Y; Refetoff S
J Clin Endocrinol Metab; 2007 Jul; 92(7):2816-20. PubMed ID: 17456567
[TBL] [Abstract][Full Text] [Related]
7. Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism.
Duprez L; Parma J; Van Sande J; Allgeier A; Leclère J; Schvartz C; Delisle MJ; Decoulx M; Orgiazzi J; Dumont J
Nat Genet; 1994 Jul; 7(3):396-401. PubMed ID: 7920658
[TBL] [Abstract][Full Text] [Related]
8. Identification of TSH receptor mutations in three families with resistance to TSH.
Tonacchera M; Di Cosmo C; De Marco G; Agretti P; Banco M; Perri A; Gianetti E; Montanelli L; Vitti P; Pinchera A
Clin Endocrinol (Oxf); 2007 Nov; 67(5):712-8. PubMed ID: 17697008
[TBL] [Abstract][Full Text] [Related]
9. Functional characterization of five constitutively activating thyrotrophin receptor mutations.
Wonerow P; Chey S; Führer D; Holzapfel HP; Paschke R
Clin Endocrinol (Oxf); 2000 Oct; 53(4):461-8. PubMed ID: 11012571
[TBL] [Abstract][Full Text] [Related]
10. Identification of separate determinants on the thyrotropin receptor reactive with Graves' thyroid-stimulating antibodies and with thyroid-stimulating blocking antibodies in idiopathic myxedema: these determinants have no homologous sequence on gonadotropin receptors.
Kosugi S; Ban T; Akamizu T; Kohn LD
Mol Endocrinol; 1992 Feb; 6(2):168-80. PubMed ID: 1349156
[TBL] [Abstract][Full Text] [Related]
11. Hyperfunctioning thyroid nodules in toxic multinodular goiter share activating thyrotropin receptor mutations with solitary toxic adenoma.
Tonacchera M; Chiovato L; Pinchera A; Agretti P; Fiore E; Cetani F; Rocchi R; Viacava P; Miccoli P; Vitti P
J Clin Endocrinol Metab; 1998 Feb; 83(2):492-8. PubMed ID: 9467563
[TBL] [Abstract][Full Text] [Related]
12. Mutations in the mouse TSH receptor equivalent to human constitutively activating TSH receptor mutations also cause constitutive activity.
Neumann S; Krohn K; Chey S; Paschke R
Horm Metab Res; 2001 May; 33(5):263-9. PubMed ID: 11440271
[TBL] [Abstract][Full Text] [Related]
13. Expression of G(alpha)(s) proteins and TSH receptor signalling in hyperfunctioning thyroid nodules with TSH receptor mutations.
Holzapfel HP; Bergner B; Wonerow P; Paschke R
Eur J Endocrinol; 2002 Jul; 147(1):109-16. PubMed ID: 12088927
[TBL] [Abstract][Full Text] [Related]
14. Congenital hypothyroidism with impaired thyroid response to thyrotropin (TSH) and absent circulating thyroglobulin: evidence for a new inactivating mutation of the TSH receptor gene.
Tonacchera M; Agretti P; Pinchera A; Rosellini V; Perri A; Collecchi P; Vitti P; Chiovato L
J Clin Endocrinol Metab; 2000 Mar; 85(3):1001-8. PubMed ID: 10720030
[TBL] [Abstract][Full Text] [Related]
15. The thyrotropin (TSH) receptor transmembrane domain mutation (Pro556-Leu) in the hypothyroid hyt/hyt mouse results in plasma membrane targeting but defective TSH binding.
Gu WX; Du GG; Kopp P; Rentoumis A; Albanese C; Kohn LD; Madison LD; Jameson JL
Endocrinology; 1995 Jul; 136(7):3146-53. PubMed ID: 7789342
[TBL] [Abstract][Full Text] [Related]
16. Proper targeting and activity of a nonfunctioning thyroid-stimulating hormone receptor (TSHr) combining an inactivating and activating TSHr mutation in one receptor.
Agretti P; De Marco G; Collecchi P; Chiovato L; Vitti P; Pinchera A; Tonacchera M
Eur J Biochem; 2003 Sep; 270(18):3839-47. PubMed ID: 12950268
[TBL] [Abstract][Full Text] [Related]
17. Thyrotropin (TSH) receptor antibodies (TSHrAb) can inhibit TSH-mediated cyclic adenosine 3',5'- monophosphate production in thyroid cells by either blocking TSH binding or affecting a step subsequent to TSH binding.
Dallas JS; Cunningham SJ; Patibandla SA; Seetharamaiah GS; Morris JC; Tahara K; Kohn LD; Prabhakar BS
Endocrinology; 1996 Aug; 137(8):3329-39. PubMed ID: 8754759
[TBL] [Abstract][Full Text] [Related]
18. The middle portion in the second cytoplasmic loop of the thyrotropin receptor plays a crucial role in adenylate cyclase activation.
Kosugi S; Kohn LD; Akamizu T; Mori T
Mol Endocrinol; 1994 Apr; 8(4):498-509. PubMed ID: 7914349
[TBL] [Abstract][Full Text] [Related]
19. Increased cyclic adenosine 3',5'-monophosphate inhibits G protein-coupled activation of phospholipase C in rat FRTL-5 thyroid cells.
Laglia G; Zeiger MA; Leipricht A; Caturegli P; Levine MA; Kohn LD; Saji M
Endocrinology; 1996 Aug; 137(8):3170-6. PubMed ID: 8754735
[TBL] [Abstract][Full Text] [Related]
20. A novel thyrotropin receptor mutation in an infant with severe thyrotoxicosis.
Esapa CT; Duprez L; Ludgate M; Mustafa MS; Kendall-Taylor P; Vassart G; Harris PE
Thyroid; 1999 Oct; 9(10):1005-10. PubMed ID: 10560955
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
