135 related articles for article (PubMed ID: 8642859)
1. Mutations in the gene for human dihydrofolate reductase: an unlikely cause of clinical relapse in pediatric leukemia after therapy with methotrexate.
Spencer HT; Sorrentino BP; Pui CH; Chunduru SK; Sleep SE; Blakley RL
Leukemia; 1996 Mar; 10(3):439-46. PubMed ID: 8642859
[TBL] [Abstract][Full Text] [Related]
2. Increasing methotrexate resistance by combination of active-site mutations in human dihydrofolate reductase.
Volpato JP; Fossati E; Pelletier JN
J Mol Biol; 2007 Oct; 373(3):599-611. PubMed ID: 17868689
[TBL] [Abstract][Full Text] [Related]
3. Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene.
Takebe N; Zhao SC; Adhikari D; Mineishi S; Sadelain M; Hilton J; Colvin M; Banerjee D; Bertino JR
Mol Ther; 2001 Jan; 3(1):88-96. PubMed ID: 11162315
[TBL] [Abstract][Full Text] [Related]
4. Protection of CCRF-CEM human lymphoid cells from antifolates by retroviral gene transfer of variants of murine dihydrofolate reductase.
Mareya SM; Sorrentino BP; Blakley RL
Cancer Gene Ther; 1998; 5(4):225-35. PubMed ID: 9694074
[TBL] [Abstract][Full Text] [Related]
5. Methotrexate selection of long-term culture initiating cells following transduction of CD34(+) cells with a retrovirus containing a mutated human dihydrofolate reductase gene.
Takebe N; Xu LC; MacKenzie KL; Bertino JR; Moore MA
Cancer Gene Ther; 2002 Mar; 9(3):308-20. PubMed ID: 11896448
[TBL] [Abstract][Full Text] [Related]
6. Co-expression of the herpes simplex virus thymidine kinase gene potentiates methotrexate resistance conferred by transfer of a mutated dihydrofolate reductase gene.
Mineishi S; Nakahara S; Takebe N; Banerjee D; Zhao SC; Bertino JR
Gene Ther; 1997 Jun; 4(6):570-6. PubMed ID: 9231073
[TBL] [Abstract][Full Text] [Related]
7. [Mice transduced with double-mutant dihydrofolate reductase-cytidine deaminase fusion gene attained protection from high dose chemotherapy].
Lu P; Lu Y; Pang K; Wang SB; Chen JQ; Xu HM; Wang JK; Zhao SC
Zhonghua Wai Ke Za Zhi; 2005 Aug; 43(15):998-1001. PubMed ID: 16194358
[TBL] [Abstract][Full Text] [Related]
8. [Double-mutant dihydrofolate reductase gene transfection into bone marrow cells protects mice from chemotherapy].
Gao HD; Lu P; Lu Y; Pang K; Xu HM; Wang SB; Chen JQ; Zhao SC
Zhonghua Zhong Liu Za Zhi; 2006 Aug; 28(8):583-5. PubMed ID: 17236551
[TBL] [Abstract][Full Text] [Related]
9. Purine salvage rescue by xanthine-guanine phosphoribosyltransferase (XGPRT) potentiates methotrexate resistance conferred by transfer of a mutated dihydrofolate reductase gene.
Mineishi S; Nakahara S; Takebe N; Zhao SC; Banerjee D; Bertino JR
Cancer Gene Ther; 1998; 5(3):144-9. PubMed ID: 9622097
[TBL] [Abstract][Full Text] [Related]
10. Comparison of methotrexate resistance conferred by a mutated dihydrofolate reductase (DHFR) cDNA in two different retroviral vectors.
Takebe N; Nakahara S; Zhao SC; Adhikari D; Ural AU; Iwamoto M; Banerjee D; Bertino JR
Cancer Gene Ther; 2000 Jun; 7(6):910-9. PubMed ID: 10880023
[TBL] [Abstract][Full Text] [Related]
11. DHFR and MSH3 co-amplification in childhood acute lymphoblastic leukaemia, in vitro and in vivo.
Matheson EC; Hogarth LA; Case MC; Irving JA; Hall AG
Carcinogenesis; 2007 Jun; 28(6):1341-6. PubMed ID: 17148505
[TBL] [Abstract][Full Text] [Related]
12. Coexpression of cytidine deaminase and mutant dihydrofolate reductase by a bicistronic retroviral vector confers resistance to cytosine arabinoside and methotrexate.
Beauséjour CM; Le NL; Létourneau S; Cournoyer D; Momparler RL
Hum Gene Ther; 1998 Nov; 9(17):2537-44. PubMed ID: 9853520
[TBL] [Abstract][Full Text] [Related]
13. Selective expression of methotrexate-resistant dihydrofolate reductase (DHFR) activity in mice transduced with DHFR retrovirus and administered methotrexate.
Vinh DB; McIvor RS
J Pharmacol Exp Ther; 1993 Nov; 267(2):989-96. PubMed ID: 8246174
[TBL] [Abstract][Full Text] [Related]
14. Molecular mechanisms of resistance to antifolates, a review.
Banerjee D; Ercikan-Abali E; Waltham M; Schnieders B; Hochhauser D; Li WW; Fan J; Gorlick R; Goker E; Bertino JR
Acta Biochim Pol; 1995; 42(4):457-64. PubMed ID: 8852336
[TBL] [Abstract][Full Text] [Related]
15. Drug-resistant dihydrofolate reductases: generation, expression and therapeutic application.
McIvor RS
Bone Marrow Transplant; 1996 Dec; 18 Suppl 3():S50-4. PubMed ID: 8971409
[TBL] [Abstract][Full Text] [Related]
16. Transgenic mice expressing the tyr22 variant of murine DHFR: protection of transgenic marrow transplant recipients from lethal doses of methotrexate.
James RI; May C; Vagt MD; Studebaker R; McIvor RS
Exp Hematol; 1997 Nov; 25(12):1286-95. PubMed ID: 9357973
[TBL] [Abstract][Full Text] [Related]
17. Influence of dihydrofolate reductase gene polymorphisms rs408626 (-317A>G) and rs442767 (-680C>A) on the outcome of methotrexate-based maintenance therapy in South Indian patients with acute lymphoblastic leukemia.
Kodidela S; Pradhan SC; Dubashi B; Basu D
Eur J Clin Pharmacol; 2015 Nov; 71(11):1349-58. PubMed ID: 26335211
[TBL] [Abstract][Full Text] [Related]
18. Methotrexate selectable retroviral vectors for Gaucher disease.
Havenga MJ; Werner AB; Valerio D; van Es HH
Gene Ther; 1998 Oct; 5(10):1379-88. PubMed ID: 9930344
[TBL] [Abstract][Full Text] [Related]
19. Saturation mutagenesis at dihydrofolate reductase codons 22 and 31. A variety of amino acid substitutions conferring methotrexate resistance.
Morris JA; McIvor RS
Biochem Pharmacol; 1994 Mar; 47(7):1207-20. PubMed ID: 8161350
[TBL] [Abstract][Full Text] [Related]
20. Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH.
Cody V; Luft JR; Pangborn W
Acta Crystallogr D Biol Crystallogr; 2005 Feb; 61(Pt 2):147-55. PubMed ID: 15681865
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]