283 related articles for article (PubMed ID: 8650234)
1. Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene.
Gladyshev VN; Jeang KT; Stadtman TC
Proc Natl Acad Sci U S A; 1996 Jun; 93(12):6146-51. PubMed ID: 8650234
[TBL] [Abstract][Full Text] [Related]
2. Heparin-binding properties of selenium-containing thioredoxin reductase from HeLa cells and human lung adenocarcinoma cells.
Liu SY; Stadtman TC
Proc Natl Acad Sci U S A; 1997 Jun; 94(12):6138-41. PubMed ID: 9177183
[TBL] [Abstract][Full Text] [Related]
3. Selenocysteine-containing thioredoxin reductase in C. elegans.
Gladyshev VN; Krause M; Xu XM; Korotkov KV; Kryukov GV; Sun QA; Lee BJ; Wootton JC; Hatfield DL
Biochem Biophys Res Commun; 1999 Jun; 259(2):244-9. PubMed ID: 10362494
[TBL] [Abstract][Full Text] [Related]
4. Rat and calf thioredoxin reductase are homologous to glutathione reductase with a carboxyl-terminal elongation containing a conserved catalytically active penultimate selenocysteine residue.
Zhong L; Arnér ES; Ljung J; Aslund F; Holmgren A
J Biol Chem; 1998 Apr; 273(15):8581-91. PubMed ID: 9535831
[TBL] [Abstract][Full Text] [Related]
5. Antioxidant function of thioredoxin and glutaredoxin systems.
Holmgren A
Antioxid Redox Signal; 2000; 2(4):811-20. PubMed ID: 11213485
[TBL] [Abstract][Full Text] [Related]
6. Mammalian thioredoxin reductase: oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity.
Lee SR; Bar-Noy S; Kwon J; Levine RL; Stadtman TC; Rhee SG
Proc Natl Acad Sci U S A; 2000 Mar; 97(6):2521-6. PubMed ID: 10688911
[TBL] [Abstract][Full Text] [Related]
7. Overexpression of wild type and SeCys/Cys mutant of human thioredoxin reductase in E. coli: the role of selenocysteine in the catalytic activity.
Bar-Noy S; Gorlatov SN; Stadtman TC
Free Radic Biol Med; 2001 Jan; 30(1):51-61. PubMed ID: 11134895
[TBL] [Abstract][Full Text] [Related]
8. Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations.
Zhong L; Holmgren A
J Biol Chem; 2000 Jun; 275(24):18121-8. PubMed ID: 10849437
[TBL] [Abstract][Full Text] [Related]
9. No selenium required: reactions catalyzed by mammalian thioredoxin reductase that are independent of a selenocysteine residue.
Lothrop AP; Ruggles EL; Hondal RJ
Biochemistry; 2009 Jul; 48(26):6213-23. PubMed ID: 19366212
[TBL] [Abstract][Full Text] [Related]
10. Cloning, sequencing and functional expression of a novel human thioredoxin reductase.
Gasdaska PY; Berggren MM; Berry MJ; Powis G
FEBS Lett; 1999 Jan; 442(1):105-11. PubMed ID: 9923614
[TBL] [Abstract][Full Text] [Related]
11. A mechanistic investigation of the C-terminal redox motif of thioredoxin reductase from Plasmodium falciparum.
Snider GW; Dustin CM; Ruggles EL; Hondal RJ
Biochemistry; 2014 Jan; 53(3):601-9. PubMed ID: 24400600
[TBL] [Abstract][Full Text] [Related]
12. Molecular cloning and characterization of a mitochondrial selenocysteine-containing thioredoxin reductase from rat liver.
Lee SR; Kim JR; Kwon KS; Yoon HW; Levine RL; Ginsburg A; Rhee SG
J Biol Chem; 1999 Feb; 274(8):4722-34. PubMed ID: 9988709
[TBL] [Abstract][Full Text] [Related]
13. Structure and mechanism of mammalian thioredoxin reductase: the active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence.
Zhong L; Arnér ES; Holmgren A
Proc Natl Acad Sci U S A; 2000 May; 97(11):5854-9. PubMed ID: 10801974
[TBL] [Abstract][Full Text] [Related]
14. Selenium and the thioredoxin and glutaredoxin systems.
Björnstedt M; Kumar S; Björkhem L; Spyrou G; Holmgren A
Biomed Environ Sci; 1997 Sep; 10(2-3):271-9. PubMed ID: 9315320
[TBL] [Abstract][Full Text] [Related]
15. Human thioredoxin reductase from HeLa cells: selective alkylation of selenocysteine in the protein inhibits enzyme activity and reduction with NADPH influences affinity to heparin.
Gorlatov SN; Stadtman TC
Proc Natl Acad Sci U S A; 1998 Jul; 95(15):8520-5. PubMed ID: 9671710
[TBL] [Abstract][Full Text] [Related]
16. Functional expression of rat thioredoxin reductase: selenocysteine insertion sequence element is essential for the active enzyme.
Fujiwara N; Fujii T; Fujii J; Taniguchi N
Biochem J; 1999 Jun; 340 ( Pt 2)(Pt 2):439-44. PubMed ID: 10333487
[TBL] [Abstract][Full Text] [Related]
17. The mutual sparing effects of selenium and vitamin E in animal nutrition may be further explained by the discovery that mammalian thioredoxin reductase is a selenoenzyme.
Tamura T; Gladyshev V; Liu SY; Stadtman TC
Biofactors; 1995-1996; 5(2):99-102. PubMed ID: 8722124
[TBL] [Abstract][Full Text] [Related]
18. Non-animal origin of animal thioredoxin reductases: implications for selenocysteine evolution and evolution of protein function through carboxy-terminal extensions.
Novoselov SV; Gladyshev VN
Protein Sci; 2003 Feb; 12(2):372-8. PubMed ID: 12538901
[TBL] [Abstract][Full Text] [Related]
19. Three-dimensional structure of a mammalian thioredoxin reductase: implications for mechanism and evolution of a selenocysteine-dependent enzyme.
Sandalova T; Zhong L; Lindqvist Y; Holmgren A; Schneider G
Proc Natl Acad Sci U S A; 2001 Aug; 98(17):9533-8. PubMed ID: 11481439
[TBL] [Abstract][Full Text] [Related]
20. Investigation of the C-terminal redox center of high-Mr thioredoxin reductase by protein engineering and semisynthesis.
Eckenroth BE; Lacey BM; Lothrop AP; Harris KM; Hondal RJ
Biochemistry; 2007 Aug; 46(33):9472-83. PubMed ID: 17661444
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]