These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

80 related articles for article (PubMed ID: 8654201)

  • 1. Metabolism and pharmacokinetics of N1,N11-diethylnorspermine.
    Bergeron RJ; Weimar WR; Luchetta G; Streiff RR; Wiegand J; Perrin J; Schreier KM; Porter C; Yao GW; Dimova H
    Drug Metab Dispos; 1995 Oct; 23(10):1117-25. PubMed ID: 8654201
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism and pharmacokinetics of N1,N14-diethylhomospermine.
    Bergeron RJ; Weimar WR; Luchetta G; Sninsky CA; Wiegand J
    Drug Metab Dispos; 1996 Mar; 24(3):334-43. PubMed ID: 8820425
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolism and pharmacokinetics of N1,N11-diethylnorspermine in a Cebus apella primate model.
    Bergeron RJ; Merriman RL; Olson SG; Wiegand J; Bender J; Streiff RR; Weimar WR
    Cancer Res; 2000 Aug; 60(16):4433-9. PubMed ID: 10969789
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Preclinical antitumor efficacy of the polyamine analogue N1, N11-diethylnorspermine administered by multiple injection or continuous infusion.
    Bernacki RJ; Oberman EJ; Seweryniak KE; Atwood A; Bergeron RJ; Porter CW
    Clin Cancer Res; 1995 Aug; 1(8):847-57. PubMed ID: 9816054
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transgenic mice with activated polyamine catabolism due to overexpression of spermidine/spermine N1-acetyltransferase show enhanced sensitivity to the polyamine analog, N1, N11-diethylnorspermine.
    Alhonen L; Pietilä M; Halmekytö M; Kramer DL; Jänne J; Porter CW
    Mol Pharmacol; 1999 Apr; 55(4):693-8. PubMed ID: 10101027
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antitumor efficacy of N1,N11-diethylnorspermine on a human bladder tumor xenograft in nude athymic mice.
    Sharma A; Glaves D; Porter CW; Raghavan D; Bernacki RJ
    Clin Cancer Res; 1997 Aug; 3(8):1239-44. PubMed ID: 9815805
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of polyamine catabolism by N1,N11-diethylnorspermine leads to cell death in glioblastoma.
    Jiang R; Choi W; Khan A; Hess K; Gerner EW; Casero RA; Yung WK; Hamilton SR; Zhang W
    Int J Oncol; 2007 Aug; 31(2):431-40. PubMed ID: 17611701
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The polyamine analogue N1,N11-diethylnorspermine can induce chondrocyte apoptosis independently of its ability to alter metabolism and levels of natural polyamines.
    Stanic' I; Facchini A; Borzì RM; Stefanelli C; Flamigni F
    J Cell Physiol; 2009 Apr; 219(1):109-16. PubMed ID: 19097065
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Induction of spermidine/spermine N1-acetyltransferase in breast cancer tissues treated with the polyamine analogue N1, N11-diethylnorspermine.
    Gabrielson E; Tully E; Hacker A; Pegg AE; Davidson NE; Casero RA
    Cancer Chemother Pharmacol; 2004 Aug; 54(2):122-6. PubMed ID: 15138709
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lysosomal sequestration of polyamine analogues in Chinese hamster ovary cells resistant to the S-adenosylmethionine decarboxylase inhibitor, CGP-48664.
    Kramer DL; Black JD; Mett H; Bergeron RJ; Porter CW
    Cancer Res; 1998 Sep; 58(17):3883-90. PubMed ID: 9731498
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Apoptosis induced by the potential chemotherapeutic drug N1, N11-Diethylnorspermine in a neuroblastoma cell line.
    Söderstjerna E; Holst CM; Alm K; Oredsson SM
    Anticancer Drugs; 2010 Nov; 21(10):917-26. PubMed ID: 20729713
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Phase II study of the polyamine analog N1,N11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer.
    Wolff AC; Armstrong DK; Fetting JH; Carducci MK; Riley CD; Bender JF; Casero RA; Davidson NE
    Clin Cancer Res; 2003 Dec; 9(16 Pt 1):5922-8. PubMed ID: 14676116
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells.
    Choi W; Gerner EW; Ramdas L; Dupart J; Carew J; Proctor L; Huang P; Zhang W; Hamilton SR
    J Biol Chem; 2005 Feb; 280(5):3295-304. PubMed ID: 15546879
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Correlation of polyamine and growth responses to N1,N11-diethylnorspermine in primary fetal fibroblasts derived from transgenic mice overexpressing spermidine/spermine N1-acetyltransferase.
    Alhonen L; Karppinen A; Uusi-Oukari M; Vujcic S; Korhonen VP; Halmekytö M; Kramer DL; Hines R; Jänne J; Porter CW
    J Biol Chem; 1998 Jan; 273(4):1964-9. PubMed ID: 9442032
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of inhibitor of apoptosis proteins as a determinant of polyamine analog-induced apoptosis in human melanoma cells.
    Chen Y; Kramer DL; Li F; Porter CW
    Oncogene; 2003 Aug; 22(32):4964-72. PubMed ID: 12902979
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular mechanisms underlying N1, N11-diethylnorspermine-induced apoptosis in a human breast cancer cell line.
    Holst CM; Staaf J; Jönsson G; Hegardt C; Oredsson SM
    Anticancer Drugs; 2008 Oct; 19(9):871-83. PubMed ID: 18766001
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Preclinical toxicologic evaluation of DENSPM (N1,N11-diethylnorspermine) in rats and dogs.
    Kanter PM; Bullard GA; King JM
    Anticancer Drugs; 1994 Aug; 5(4):448-56. PubMed ID: 7949250
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of polyamines, polyamine analogs, and inhibitors of protein synthesis on spermidine-spermine N1-acetyltransferase gene expression.
    Fogel-Petrovic M; Vujcic S; Brown PJ; Haddox MK; Porter CW
    Biochemistry; 1996 Nov; 35(45):14436-44. PubMed ID: 8916930
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Small interfering RNA suppression of polyamine analog-induced spermidine/spermine n1-acetyltransferase.
    Chen Y; Kramer DL; Jell J; Vujcic S; Porter CW
    Mol Pharmacol; 2003 Nov; 64(5):1153-9. PubMed ID: 14573765
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sequence specific antisense oligonucleotide analog interference with spermidine/spermine N1-acetyltransferase gene expression.
    Fogel-Petrovic M; Vujcic S; Häner R; Regenass U; Mett H; Porter CW
    Anticancer Res; 1996; 16(5A):2517-23. PubMed ID: 8917345
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.