These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 8660394)

  • 1. Radicals from one-electron reduction of nitro compounds, aromatic N-oxides and quinones: the kinetic basis for hypoxia-selective, bioreductive drugs.
    Wardman P; Dennis MF; Everett SA; Patel KB; Stratford MR; Tracy M
    Biochem Soc Symp; 1995; 61():171-94. PubMed ID: 8660394
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Electron transfer and oxidative stress as key factors in the design of drugs selectively active in hypoxia.
    Wardman P
    Curr Med Chem; 2001 Jun; 8(7):739-61. PubMed ID: 11375747
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chemical properties which control selectivity and efficacy of aromatic N-oxide bioreductive drugs.
    Wardman P; Priyadarsini KI; Dennis MF; Everett SA; Naylor MA; Patel KB; Stratford IJ; Stratford MR; Tracy M
    Br J Cancer Suppl; 1996 Jul; 27():S70-4. PubMed ID: 8763850
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Indolequinone bioreductive drugs: kinetic factors which influence selectivity for hypoxia.
    Everett SA; Naylor MA; Nolan J; Patel KB; Wardman P
    Anticancer Drug Des; 1998 Sep; 13(6):635-53. PubMed ID: 9755722
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Radical Chemistry and Cytotoxicity of Bioreductive 3-Substituted Quinoxaline Di-N-Oxides.
    Anderson RF; Yadav P; Shinde SS; Hong CR; Pullen SM; Reynisson J; Wilson WR; Hay MP
    Chem Res Toxicol; 2016 Aug; 29(8):1310-24. PubMed ID: 27380897
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Electron transfer reactions in RB90745, a bioreductive drug having both aromatic N-oxide and nitroarene moieties.
    Priyadarsini KI; Naylor MA; Stratford MR; Wardman P
    Free Radic Res; 1996 Aug; 25(2):99-107. PubMed ID: 8885327
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nitracrine N-oxides: effects of variations in the nature of the side chain N-oxide on hypoxia-selective cytotoxicity.
    Lee HH; Wilson WR; Denny WA
    Anticancer Drug Des; 1999 Dec; 14(6):487-97. PubMed ID: 10834270
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bioreductive activation of quinones: a mixed blessing.
    Koster AS
    Pharm Weekbl Sci; 1991 Jun; 13(3):123-6. PubMed ID: 1923701
    [TBL] [Abstract][Full Text] [Related]  

  • 9. One- and two-electron reduction of 2-methyl-1,4-naphthoquinone bioreductive alkylating agents: kinetic studies, free-radical production, thiol oxidation and DNA-strand-break formation.
    Giulivi C; Cadenas E
    Biochem J; 1994 Jul; 301 ( Pt 1)(Pt 1):21-30. PubMed ID: 8037673
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oxidation of 2-deoxyribose by benzotriazinyl radicals of antitumor 3-amino-1,2,4-benzotriazine 1,4-dioxides.
    Shinde SS; Anderson RF; Hay MP; Gamage SA; Denny WA
    J Am Chem Soc; 2004 Jun; 126(25):7865-74. PubMed ID: 15212534
    [TBL] [Abstract][Full Text] [Related]  

  • 11. One-electron reduction of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin: a pulse radiolysis study.
    Goldstein S
    J Phys Chem A; 2011 Aug; 115(32):8928-32. PubMed ID: 21718076
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolic and radiolytic reduction of 4-alkylamino-5-nitroquinoline bioreductive drugs. Relationship to hypoxia-selective cytotoxicity.
    Siim BG; Atwell GJ; Wilson WR
    Biochem Pharmacol; 1994 Oct; 48(8):1593-604. PubMed ID: 7980625
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Electrochemical parameters and techniques in drug development, with an emphasis on quinones and related compounds.
    Hillard EA; de Abreu FC; Ferreira DC; Jaouen G; Goulart MO; Amatore C
    Chem Commun (Camb); 2008 Jun; (23):2612-28. PubMed ID: 18535688
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Potentiation of the cytotoxicity of the anticancer agent tirapazamine by benzotriazine N-oxides: the role of redox equilibria.
    Anderson RF; Shinde SS; Hay MP; Denny WA
    J Am Chem Soc; 2006 Jan; 128(1):245-9. PubMed ID: 16390153
    [TBL] [Abstract][Full Text] [Related]  

  • 15. One-electron reduction of quinones by the neuronal nitric-oxide synthase reductase domain.
    Matsuda H; Kimura S; Iyanagi T
    Biochim Biophys Acta; 2000 Jul; 1459(1):106-16. PubMed ID: 10924903
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Redox cycling of radical anion metabolites of toxic chemicals and drugs and the Marcus theory of electron transfer.
    Mason RP
    Environ Health Perspect; 1990 Jul; 87():237-43. PubMed ID: 2176587
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nicotinamide adenine dinucleotide (phosphate): quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumor quinones: quinone cytotoxicity and selectivity in human lung and breast cancer cell lines.
    Beall HD; Murphy AM; Siegel D; Hargreaves RH; Butler J; Ross D
    Mol Pharmacol; 1995 Sep; 48(3):499-504. PubMed ID: 7565631
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Futile redox cycling: implications for oxygen radical toxicity.
    Hochstein P
    Fundam Appl Toxicol; 1983; 3(4):215-7. PubMed ID: 6313461
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antagonism in effectiveness of evofosfamide and doxorubicin through intermolecular electron transfer.
    Anderson RF; Li D; Hunter FW
    Free Radic Biol Med; 2017 Dec; 113():564-570. PubMed ID: 29111232
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The one-electron reduction potential of 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine): a hypoxia-selective bioreductive drug.
    Priyadarsini KI; Tracy M; Wardman P
    Free Radic Res; 1996 Nov; 25(5):393-9. PubMed ID: 8902537
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.