BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

106 related articles for article (PubMed ID: 8660990)

  • 1. Assignment of the human FKBP12-rapamycin-associated protein (FRAP) gene to chromosome 1p36 by fluorescence in situ hybridization.
    Moore PA; Rosen CA; Carter KC
    Genomics; 1996 Apr; 33(2):331-2. PubMed ID: 8660990
    [No Abstract]   [Full Text] [Related]  

  • 2. A mammalian protein targeted by G1-arresting rapamycin-receptor complex.
    Brown EJ; Albers MW; Shin TB; Ichikawa K; Keith CT; Lane WS; Schreiber SL
    Nature; 1994 Jun; 369(6483):756-8. PubMed ID: 8008069
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP.
    Choi J; Chen J; Schreiber SL; Clardy J
    Science; 1996 Jul; 273(5272):239-42. PubMed ID: 8662507
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Control of p70 s6 kinase by kinase activity of FRAP in vivo.
    Brown EJ; Beal PA; Keith CT; Chen J; Shin TB; Schreiber SL
    Nature; 1995 Oct; 377(6548):441-6. PubMed ID: 7566123
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-activity studies of rapamycin analogs: evidence that the C-7 methoxy group is part of the effector domain and positioned at the FKBP12-FRAP interface.
    Luengo JI; Yamashita DS; Dunnington D; Beck AK; Rozamus LW; Yen HK; Bossard MJ; Levy MA; Hand A; Newman-Tarr T
    Chem Biol; 1995 Jul; 2(7):471-81. PubMed ID: 9383449
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Immunophilins, ligands, and the control of signal transduction.
    Schreiber SL; Crabtree GR
    Harvey Lect; 1995-1996; 91():99-114. PubMed ID: 9127988
    [No Abstract]   [Full Text] [Related]  

  • 7. Protein matchmaker may lead new gene therapy to the altar.
    Balter M
    Science; 1996 Jul; 273(5272):183. PubMed ID: 8668994
    [No Abstract]   [Full Text] [Related]  

  • 8. Immunosuppressor binding to the immunophilin FKBP59 affects the local structural dynamics of a surface beta-strand: time-resolved fluorescence study.
    Rouviere N; Vincent M; Craescu CT; Gallay J
    Biochemistry; 1997 Jun; 36(24):7339-52. PubMed ID: 9200682
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cyclosporin A, FK506, and rapamycin: binding to immunophilins and biological action.
    Bierer BE
    Chem Immunol; 1994; 59():128-55. PubMed ID: 7524531
    [No Abstract]   [Full Text] [Related]  

  • 10. Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells.
    Sabers CJ; Martin MM; Brunn GJ; Williams JM; Dumont FJ; Wiederrecht G; Abraham RT
    J Biol Chem; 1995 Jan; 270(2):815-22. PubMed ID: 7822316
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin.
    Lorenz MC; Heitman J
    J Biol Chem; 1995 Nov; 270(46):27531-7. PubMed ID: 7499212
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The human gene encoding FKBP-rapamycin associated protein (FRAP) maps to chromosomal band 1p36.2.
    Lench NJ; Macadam R; Markham AF
    Hum Genet; 1997 Apr; 99(4):547-9. PubMed ID: 9099849
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interaction between FKBP12-rapamycin and TOR involves a conserved serine residue.
    Stan R; McLaughlin MM; Cafferkey R; Johnson RK; Rosenberg M; Livi GP
    J Biol Chem; 1994 Dec; 269(51):32027-30. PubMed ID: 7528205
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Consensus preferred hydration sites in six FKBP12-drug complexes.
    Faerman CH; Karplus PA
    Proteins; 1995 Sep; 23(1):1-11. PubMed ID: 8539241
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue.
    Chen J; Zheng XF; Brown EJ; Schreiber SL
    Proc Natl Acad Sci U S A; 1995 May; 92(11):4947-51. PubMed ID: 7539137
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex.
    Chiu MI; Katz H; Berlin V
    Proc Natl Acad Sci U S A; 1994 Dec; 91(26):12574-8. PubMed ID: 7809080
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The rapamycin and FKBP12 target (RAFT) displays phosphatidylinositol 4-kinase activity.
    Sabatini DM; Pierchala BA; Barrow RK; Schell MJ; Snyder SH
    J Biol Chem; 1995 Sep; 270(36):20875-8. PubMed ID: 7673106
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanism of action of rapamycin (Sirolimus, Rapamune).
    Molnar-Kimber KL
    Transplant Proc; 1996 Apr; 28(2):964-9. PubMed ID: 8623482
    [No Abstract]   [Full Text] [Related]  

  • 19. Missense mutations at the FKBP12-rapamycin-binding site of TOR1.
    Freeman K; Livi GP
    Gene; 1996 Jun; 172(1):143-7. PubMed ID: 8654975
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs.
    Sabatini DM; Erdjument-Bromage H; Lui M; Tempst P; Snyder SH
    Cell; 1994 Jul; 78(1):35-43. PubMed ID: 7518356
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.