BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 8662795)

  • 1. Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation.
    Hemmann U; Gerhartz C; Heesel B; Sasse J; Kurapkat G; Grötzinger J; Wollmer A; Zhong Z; Darnell JE; Graeve L; Heinrich PC; Horn F
    J Biol Chem; 1996 May; 271(22):12999-3007. PubMed ID: 8662795
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. I. Definition of a novel phosphotyrosine motif mediating STAT1 activation.
    Gerhartz C; Heesel B; Sasse J; Hemmann U; Landgraf C; Schneider-Mergener J; Horn F; Heinrich PC; Graeve L
    J Biol Chem; 1996 May; 271(22):12991-8. PubMed ID: 8662591
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The amino acid residues immediately carboxyl-terminal to the tyrosine phosphorylation site contribute to interleukin 6-specific activation of signal transducer and activator of transcription 3.
    Inoue M; Minami M; Matsumoto M; Kishimoto T; Akira S
    J Biol Chem; 1997 Apr; 272(14):9550-5. PubMed ID: 9083098
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.
    Lütticken C; Wegenka UM; Yuan J; Buschmann J; Schindler C; Ziemiecki A; Harpur AG; Wilks AF; Yasukawa K; Taga T
    Science; 1994 Jan; 263(5143):89-92. PubMed ID: 8272872
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family.
    Wegenka UM; Lütticken C; Buschmann J; Yuan J; Lottspeich F; Müller-Esterl W; Schindler C; Roeb E; Heinrich PC; Horn F
    Mol Cell Biol; 1994 May; 14(5):3186-96. PubMed ID: 8164674
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
    Schaper F; Gendo C; Eck M; Schmitz J; Grimm C; Anhuf D; Kerr IM; Heinrich PC
    Biochem J; 1998 Nov; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of phosphopeptide motifs specific for the Src homology 2 domains of signal transducer and activator of transcription 1 (STAT1) and STAT3.
    Wiederkehr-Adam M; Ernst P; Müller K; Bieck E; Gombert FO; Ottl J; Graff P; Grossmüller F; Heim MH
    J Biol Chem; 2003 May; 278(18):16117-28. PubMed ID: 12591923
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The carboxyl-terminal domains of gp130-related cytokine receptors are necessary for suppressing embryonic stem cell differentiation. Involvement of STAT3.
    Ernst M; Novak U; Nicholson SE; Layton JE; Dunn AR
    J Biol Chem; 1999 Apr; 274(14):9729-37. PubMed ID: 10092661
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.
    Bode JG; Schweigart J; Kehrmann J; Ehlting C; Schaper F; Heinrich PC; Häussinger D
    J Immunol; 2003 Jul; 171(1):257-66. PubMed ID: 12817006
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Signal transducer and activator of transcription STAT3 plays a major role in gp130-mediated acute phase protein gene activation.
    May P; Schniertshauer U; Gerhartz C; Horn F; Heinrich PC
    Acta Biochim Pol; 2003; 50(3):595-601. PubMed ID: 14515142
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutational analysis of acute-phase response factor/Stat3 activation and dimerization.
    Sasse J; Hemmann U; Schwartz C; Schniertshauer U; Heesel B; Landgraf C; Schneider-Mergener J; Heinrich PC; Horn F
    Mol Cell Biol; 1997 Aug; 17(8):4677-86. PubMed ID: 9234724
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Contributions of leukemia inhibitory factor receptor and oncostatin M receptor to signal transduction in heterodimeric complexes with glycoprotein 130.
    Hermanns HM; Radtke S; Haan C; Schmitz-Van de Leur H; Tavernier J; Heinrich PC; Behrmann I
    J Immunol; 1999 Dec; 163(12):6651-8. PubMed ID: 10586060
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6.
    Zhang T; Kee WH; Seow KT; Fung W; Cao X
    Mol Cell Biol; 2000 Oct; 20(19):7132-9. PubMed ID: 10982829
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals.
    Gupta S; Yan H; Wong LH; Ralph S; Krolewski J; Schindler C
    EMBO J; 1996 Mar; 15(5):1075-84. PubMed ID: 8605877
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions.
    Dahmen H; Horsten U; Küster A; Jacques Y; Minvielle S; Kerr IM; Ciliberto G; Paonessa G; Heinrich PC; Müller-Newen G
    Biochem J; 1998 May; 331 ( Pt 3)(Pt 3):695-702. PubMed ID: 9560294
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential inhibition of IL-6-type cytokine-induced STAT activation by PMA.
    Terstegen L; Maassen BG; Radtke S; Behrmann I; Schaper F; Heinrich PC; Graeve L; Gatsios P
    FEBS Lett; 2000 Jul; 478(1-2):100-4. PubMed ID: 10922477
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway.
    Heinrich PC; Behrmann I; Müller-Newen G; Schaper F; Graeve L
    Biochem J; 1998 Sep; 334 ( Pt 2)(Pt 2):297-314. PubMed ID: 9716487
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling.
    Li X; Leung S; Kerr IM; Stark GR
    Mol Cell Biol; 1997 Apr; 17(4):2048-56. PubMed ID: 9121453
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein kinase C delta associates with the interleukin-6 receptor subunit glycoprotein (gp) 130 via Stat3 and enhances Stat3-gp130 interaction.
    Novotny-Diermayr V; Zhang T; Gu L; Cao X
    J Biol Chem; 2002 Dec; 277(51):49134-42. PubMed ID: 12361954
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Receptors for interleukin (IL)-10 and IL-6-type cytokines use similar signaling mechanisms for inducing transcription through IL-6 response elements.
    Lai CF; Ripperger J; Morella KK; Jurlander J; Hawley TS; Carson WE; Kordula T; Caligiuri MA; Hawley RG; Fey GH; Baumann H
    J Biol Chem; 1996 Jun; 271(24):13968-75. PubMed ID: 8662928
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.