These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 8670099)

  • 1. Tissue Factor residue Asp44 regulates catalytic function of the bound proteinase Factor VIIa.
    Kelly CR; Schullek JR; Ruf W; Edgington TS
    Biochem J; 1996 Apr; 315 ( Pt 1)(Pt 1):145-51. PubMed ID: 8670099
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of residue Phe225 in the cofactor-mediated, allosteric regulation of the serine protease coagulation factor VIIa.
    Petrovan RJ; Ruf W
    Biochemistry; 2000 Nov; 39(47):14457-63. PubMed ID: 11087398
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Influence of mutations in tissue factor on the fine specificity of macromolecular substrate activation.
    Dittmar S; Ruf W; Edgington TS
    Biochem J; 1997 Feb; 321 ( Pt 3)(Pt 3):787-93. PubMed ID: 9032467
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Substitution of aspartic acid for methionine-306 in factor VIIa abolishes the allosteric linkage between the active site and the binding interface with tissue factor.
    Persson E; Nielsen LS; Olsen OH
    Biochemistry; 2001 Mar; 40(11):3251-6. PubMed ID: 11258943
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of surface residues mediating tissue factor binding and catalytic function of the serine protease factor VIIa.
    Dickinson CD; Kelly CR; Ruf W
    Proc Natl Acad Sci U S A; 1996 Dec; 93(25):14379-84. PubMed ID: 8962059
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Macromolecular substrate affinity for the tissue factor-factor VIIa complex is independent of scissile bond docking.
    Shobe J; Dickinson CD; Edgington TS; Ruf W
    J Biol Chem; 1999 Aug; 274(34):24171-5. PubMed ID: 10446191
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Residue Met(156) contributes to the labile enzyme conformation of coagulation factor VIIa.
    Petrovan RJ; Ruf W
    J Biol Chem; 2001 Mar; 276(9):6616-20. PubMed ID: 11078728
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Importance of factor VIIa Gla-domain residue Arg-36 for recognition of the macromolecular substrate factor X Gla-domain.
    Ruf W; Shobe J; Rao SM; Dickinson CD; Olson A; Edgington TS
    Biochemistry; 1999 Feb; 38(7):1957-66. PubMed ID: 10026279
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cofactor residues lysine 165 and 166 are critical for protein substrate recognition by the tissue factor-factor VIIa protease complex.
    Ruf W; Miles DJ; Rehemtulla A; Edgington TS
    J Biol Chem; 1992 Mar; 267(9):6375-81. PubMed ID: 1372908
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Factor VIIa residue Arg290 is required for efficient activation of the macromolecular substrate factor X.
    Ruf W
    Biochemistry; 1994 Sep; 33(38):11631-6. PubMed ID: 7918377
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The cofactor function of the N-terminal domain of tissue factor.
    Kittur FS; Manithody C; Morrissey JH; Rezaie AR
    J Biol Chem; 2004 Sep; 279(38):39745-9. PubMed ID: 15252050
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ca2+ binding to the first epidermal growth factor module of coagulation factor VIIa is important for cofactor interaction and proteolytic function.
    Kelly CR; Dickinson CD; Ruf W
    J Biol Chem; 1997 Jul; 272(28):17467-72. PubMed ID: 9211891
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Key ligand interface residues in tissue factor contribute independently to factor VIIa binding.
    Schullek JR; Ruf W; Edgington TS
    J Biol Chem; 1994 Jul; 269(30):19399-403. PubMed ID: 8034706
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of zymogenicity-determining residues of coagulation factor VII/VIIa in cofactor interaction and macromolecular substrate recognition.
    Petrovan RJ; Ruf W
    Biochemistry; 2002 Jul; 41(30):9302-9. PubMed ID: 12135351
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dimerization of tissue factor supports solution-phase autoactivation of factor VII without influencing proteolytic activation of factor X.
    Doñate F; Kelly CR; Ruf W; Edgington TS
    Biochemistry; 2000 Sep; 39(37):11467-76. PubMed ID: 10985793
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High affinity Ca(2+)-binding site in the serine protease domain of human factor VIIa and its role in tissue factor binding and development of catalytic activity.
    Sabharwal AK; Birktoft JJ; Gorka J; Wildgoose P; Petersen LC; Bajaj SP
    J Biol Chem; 1995 Jun; 270(26):15523-30. PubMed ID: 7797546
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Requirement for binding of catalytically active factor VIIa in tissue factor-dependent experimental metastasis.
    Mueller BM; Ruf W
    J Clin Invest; 1998 Apr; 101(7):1372-8. PubMed ID: 9525979
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The biochemical basis for the apparent defect of soluble mutant tissue factor in enhancing the proteolytic activities of factor VIIa.
    Fiore MM; Neuenschwander PF; Morrissey JH
    J Biol Chem; 1994 Jan; 269(1):143-9. PubMed ID: 8276788
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Similar molecular interactions of factor VII and factor VIIa with the tissue factor region that allosterically regulates enzyme activity.
    Kelley RF; Yang J; Eigenbrot C; Moran P; Peek M; Lipari MT; Kirchhofer D
    Biochemistry; 2004 Feb; 43(5):1223-9. PubMed ID: 14756558
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of catalytic cleft and exosite residues of factor VIIa for complex formation with tissue factor pathway inhibitor.
    Iakhiaev A; Ruf W; Rao LV
    Thromb Haemost; 2001 Mar; 85(3):458-63. PubMed ID: 11307815
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.