These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

652 related articles for article (PubMed ID: 8679538)

  • 1. Characterization of the P2' and P3' specificities of thrombin using fluorescence-quenched substrates and mapping of the subsites by mutagenesis.
    Le Bonniec BF; Myles T; Johnson T; Knight CG; Tapparelli C; Stone SR
    Biochemistry; 1996 Jun; 35(22):7114-22. PubMed ID: 8679538
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures.
    Slon-Usakiewicz JJ; Sivaraman J; Li Y; Cygler M; Konishi Y
    Biochemistry; 2000 Mar; 39(9):2384-91. PubMed ID: 10694407
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Kinetic and modeling studies of S3-S3' subsites of HIV proteinases.
    Tözsér J; Weber IT; Gustchina A; Bláha I; Copeland TD; Louis JM; Oroszlan S
    Biochemistry; 1992 May; 31(20):4793-800. PubMed ID: 1591240
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Arg143 and Lys192 of the human mast cell chymase mediate the preference for acidic amino acids in position P2' of substrates.
    Andersson MK; Thorpe M; Hellman L
    FEBS J; 2010 May; 277(10):2255-67. PubMed ID: 20423454
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cleavage efficiency of the novel aspartic protease yapsin 1 (Yap3p) enhanced for substrates with arginine residues flanking the P1 site: correlation with electronegative active-site pockets predicted by molecular modeling.
    Olsen V; Guruprasad K; Cawley NX; Chen HC; Blundell TL; Loh YP
    Biochemistry; 1998 Mar; 37(9):2768-77. PubMed ID: 9485427
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cathepsin B carboxydipeptidase specificity analysis using internally quenched fluorescent peptides.
    Cezari MH; Puzer L; Juliano MA; Carmona AK; Juliano L
    Biochem J; 2002 Nov; 368(Pt 1):365-9. PubMed ID: 12201820
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bovine thrombin complexed with an uncleavable analog of residues 7-19 of fibrinogen A alpha: geometry of the catalytic triad and interactions of the P1', P2', and P3' substrate residues.
    Martin PD; Malkowski MG; DiMaio J; Konishi Y; Ni F; Edwards BF
    Biochemistry; 1996 Oct; 35(40):13030-9. PubMed ID: 8855938
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modification of the substrate specificity of porcine pepsin for the enzymatic production of bovine hide gelatin.
    Galea CA; Dalrymple BP; Kuypers R; Blakeley R
    Protein Sci; 2000 Oct; 9(10):1947-59. PubMed ID: 11106168
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rational design and selection of bivalent peptide ligands of thrombin incorporating P4-P1 tetrapeptide sequences: from good substrates to potent inhibitors.
    Su Z; Vinogradova A; Koutychenko A; Tolkatchev D; Ni F
    Protein Eng Des Sel; 2004 Aug; 17(8):647-57. PubMed ID: 15358856
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition.
    Fang B; Boross PI; Tozser J; Weber IT
    J Mol Biol; 2006 Jul; 360(3):654-66. PubMed ID: 16781734
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Determination of the P1', P2' and P3' subsite-specificity of factor Xa.
    Ludeman JP; Pike RN; Bromfield KM; Duggan PJ; Cianci J; Le Bonniec B; Whisstock JC; Bottomley SP
    Int J Biochem Cell Biol; 2003 Feb; 35(2):221-5. PubMed ID: 12479872
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Full or partial substitution of the reactive center loop of alpha-1-proteinase inhibitor by that of heparin cofactor II: P1 Arg is required for maximal thrombin inhibition.
    Filion ML; Bhakta V; Nguyen LH; Liaw PS; Sheffield WP
    Biochemistry; 2004 Nov; 43(46):14864-72. PubMed ID: 15544357
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Substrate specificity of insect trypsins and the role of their subsites in catalysis.
    Lopes AR; Juliano MA; Marana SR; Juliano L; Terra WR
    Insect Biochem Mol Biol; 2006 Feb; 36(2):130-40. PubMed ID: 16431280
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of Tyr605 and Ala607 of thimet oligopeptidase and Tyr606 and Gly608 of neurolysin in substrate hydrolysis and inhibitor binding.
    Machado MF; Rioli V; Dalio FM; Castro LM; Juliano MA; Tersariol IL; Ferro ES; Juliano L; Oliveira V
    Biochem J; 2007 Jun; 404(2):279-88. PubMed ID: 17313369
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differences in substrate and inhibitor sequence specificity of human, mouse and rat tissue kallikreins.
    Fogaça SE; Melo RL; Pimenta DC; Hosoi K; Juliano L; Juliano MA
    Biochem J; 2004 Jun; 380(Pt 3):775-81. PubMed ID: 15040788
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of Leu99 of thrombin in determining the P2 specificity of serpins.
    Rezaie AR
    Biochemistry; 1997 Jun; 36(24):7437-46. PubMed ID: 9200692
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Contribution of lysine 60f to S1' specificity of thrombin.
    Rezaie AR; Olson ST
    Biochemistry; 1997 Feb; 36(5):1026-33. PubMed ID: 9033392
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Subsite preferences of pepstatin-insensitive carboxyl proteinases from bacteria.
    Narutaki S; Dunn BM; Oda K
    J Biochem; 1999 Jan; 125(1):75-81. PubMed ID: 9880800
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of kininogenase activity of an acidic proteinase isolated from human kidney.
    Gomes RA; Juliano L; Chagas JR; Hial V
    Can J Physiol Pharmacol; 1997 Jun; 75(6):757-61. PubMed ID: 9276160
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Proton inventory studies of alpha-thrombin-catalyzed reactions of substrates with selected P and P' sites.
    Enyedy EJ; Kovach IM
    J Am Chem Soc; 2004 May; 126(19):6017-24. PubMed ID: 15137766
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.