BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 8679616)

  • 1. Alterations to the primer grip of p66 HIV-1 reverse transcriptase and their consequences for template-primer utilization.
    Ghosh M; Jacques PS; Rodgers DW; Ottman M; Darlix JL; Le Grice SF
    Biochemistry; 1996 Jul; 35(26):8553-62. PubMed ID: 8679616
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutating the "primer grip" of p66 HIV-1 reverse transcriptase implicates tryptophan-229 in template-primer utilization.
    Jacques PS; Wöhrl BM; Ottmann M; Darlix JL; Le Grice SF
    J Biol Chem; 1994 Oct; 269(42):26472-8. PubMed ID: 7523408
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The p51 subunit of human immunodeficiency virus type 1 reverse transcriptase is essential in loading the p66 subunit on the template primer.
    Harris D; Lee R; Misra HS; Pandey PK; Pandey VN
    Biochemistry; 1998 Apr; 37(17):5903-8. PubMed ID: 9558323
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution.
    Ding J; Das K; Hsiou Y; Sarafianos SG; Clark AD; Jacobo-Molina A; Tantillo C; Hughes SH; Arnold E
    J Mol Biol; 1998 Dec; 284(4):1095-111. PubMed ID: 9837729
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain.
    Najmudin S; Coté ML; Sun D; Yohannan S; Montano SP; Gu J; Georgiadis MM
    J Mol Biol; 2000 Feb; 296(2):613-32. PubMed ID: 10669612
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of mutations in the polymerase domain on the polymerase, RNase H and strand transfer activities of human immunodeficiency virus type 1 reverse transcriptase.
    Gao HQ; Boyer PL; Arnold E; Hughes SH
    J Mol Biol; 1998 Apr; 277(3):559-72. PubMed ID: 9533880
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutating a conserved motif of the HIV-1 reverse transcriptase palm subdomain alters primer utilization.
    Ghosh M; Williams J; Powell MD; Levin JG; Le Grice SF
    Biochemistry; 1997 May; 36(19):5758-68. PubMed ID: 9153416
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis.
    Pandey VN; Kaushik N; Rege N; Sarafianos SG; Yadav PN; Modak MJ
    Biochemistry; 1996 Feb; 35(7):2168-79. PubMed ID: 8652558
    [TBL] [Abstract][Full Text] [Related]  

  • 9. HIV-1 reverse transcriptase interaction with model RNA-DNA duplexes.
    Gorshkova II; Rausch JW; Le Grice SF; Crouch RJ
    Anal Biochem; 2001 Apr; 291(2):198-206. PubMed ID: 11401293
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutations in the RNase H primer grip domain of murine leukemia virus reverse transcriptase decrease efficiency and accuracy of plus-strand DNA transfer.
    Mbisa JL; Nikolenko GN; Pathak VK
    J Virol; 2005 Jan; 79(1):419-27. PubMed ID: 15596835
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Involvement of C-terminal structural elements of equine infectious anemia virus reverse transcriptase in DNA polymerase and ribonuclease H activities.
    Rausch JW; Arts EJ; Wöhrl BM; Le Grice SF
    J Mol Biol; 1996 Apr; 257(3):500-11. PubMed ID: 8648620
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Buried surface analysis of HIV-1 reverse transcriptase p66/p51 heterodimer and its interaction with dsDNA template/primer.
    Ding J; Jacobo-Molina A; Tantillo C; Lu X; Nanni RG; Arnold E
    J Mol Recognit; 1994 Jun; 7(2):157-61. PubMed ID: 7530020
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of glutamine-151 of human immunodeficiency virus type-1 reverse transcriptase in RNA-directed DNA synthesis.
    Kaushik N; Harris D; Rege N; Modak MJ; Yadav PN; Pandey VN
    Biochemistry; 1997 Nov; 36(47):14430-8. PubMed ID: 9398161
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protein-nucleic acid interactions and DNA conformation in a complex of human immunodeficiency virus type 1 reverse transcriptase with a double-stranded DNA template-primer.
    Ding J; Hughes SH; Arnold E
    Biopolymers; 1997; 44(2):125-38. PubMed ID: 9354757
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Similarities and differences in the RNase H activities of human immunodeficiency virus type 1 reverse transcriptase and Moloney murine leukemia virus reverse transcriptase.
    Gao HQ; Sarafianos SG; Arnold E; Hughes SH
    J Mol Biol; 1999 Dec; 294(5):1097-113. PubMed ID: 10600369
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutational analysis of the fingers and palm subdomains of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase.
    Boyer PL; Ferris AL; Clark P; Whitmer J; Frank P; Tantillo C; Arnold E; Hughes SH
    J Mol Biol; 1994 Oct; 243(3):472-83. PubMed ID: 7525967
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Disruption of a salt bridge between Asp 488 and Lys 465 in HIV-1 reverse transcriptase alters its proteolytic processing and polymerase activity.
    Goobar-Larsson L; Bäckbro K; Unge T; Bhikhabhai R; Vrang L; Zhang H; Orvell C; Strandberg B; Oberg B
    Virology; 1993 Oct; 196(2):731-8. PubMed ID: 7690504
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation.
    Fan N; Rank KB; Slade DE; Poppe SM; Evans DB; Kopta LA; Olmsted RA; Thomas RC; Tarpley WG; Sharma SK
    Biochemistry; 1996 Jul; 35(30):9737-45. PubMed ID: 8703945
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Studies on the effects of truncating alpha-helix E' of p66 human immunodeficiency virus type 1 reverse transcriptase on template-primer binding and fidelity of DNA synthesis.
    Menéndez-Arias L
    Biochemistry; 1998 Nov; 37(47):16636-44. PubMed ID: 9843431
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Relationship between enzyme activity and dimeric structure of recombinant HIV-1 reverse transcriptase.
    Tachedjian G; Radzio J; Sluis-Cremer N
    Proteins; 2005 Jul; 60(1):5-13. PubMed ID: 15852304
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.