These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

535 related articles for article (PubMed ID: 8681486)

  • 1. Antipyrine as a probe for human oxidative drug metabolism: identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation.
    Engel G; Hofmann U; Heidemann H; Cosme J; Eichelbaum M
    Clin Pharmacol Ther; 1996 Jun; 59(6):613-23. PubMed ID: 8681486
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of the human hepatic cytochromes P450 involved in the in vitro oxidation of antipyrine.
    Sharer JE; Wrighton SA
    Drug Metab Dispos; 1996 Apr; 24(4):487-94. PubMed ID: 8801065
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro biotransformation and identification of human cytochrome P450 isozyme-dependent metabolism of tazofelone.
    Surapaneni SS; Clay MP; Spangle LA; Paschal JW; Lindstrom TD
    Drug Metab Dispos; 1997 Dec; 25(12):1383-8. PubMed ID: 9394028
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites.
    Botsch S; Gautier JC; Beaune P; Eichelbaum M; Kroemer HK
    Mol Pharmacol; 1993 Jan; 43(1):120-6. PubMed ID: 8423765
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of the human P-450 enzymes responsible for the sulfoxidation and thiono-oxidation of diethyldithiocarbamate methyl ester: role of P-450 enzymes in disulfiram bioactivation.
    Madan A; Parkinson A; Faiman MD
    Alcohol Clin Exp Res; 1998 Sep; 22(6):1212-9. PubMed ID: 9756035
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of the cytochrome P450 enzymes involved in the metabolism of a new cardioprotective agent KR-33028.
    Kim H; Yoon YJ; Kim H; Kang S; Cheon HG; Yoo SE; Shin JG; Liu KH
    Toxicol Lett; 2006 Oct; 166(2):105-14. PubMed ID: 16857327
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: roles of cytochromes P450 2C9, 2C19, and 3A4.
    Komatsu T; Yamazaki H; Asahi S; Gillam EM; Guengerich FP; Nakajima M; Yokoi T
    Drug Metab Dispos; 2000 Nov; 28(11):1361-8. PubMed ID: 11038165
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of human cytochrome P450 and flavin-containing monooxygenase enzymes involved in the metabolism of lorcaserin, a novel selective human 5-hydroxytryptamine 2C agonist.
    Usmani KA; Chen WG; Sadeque AJ
    Drug Metab Dispos; 2012 Apr; 40(4):761-71. PubMed ID: 22266842
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of the human liver cytochrome P450 isoenzyme responsible for the 6-methylhydroxylation of the novel anticancer drug 5,6-dimethylxanthenone-4-acetic acid.
    Zhou S; Paxton JW; Tingle MD; Kestell P
    Drug Metab Dispos; 2000 Dec; 28(12):1449-56. PubMed ID: 11095582
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [O-methyl 14C]naproxen O-demethylase activity in human liver microsomes: evidence for the involvement of cytochrome P4501A2 and P4502C9/10.
    Rodrigues AD; Kukulka MJ; Roberts EM; Ouellet D; Rodgers TR
    Drug Metab Dispos; 1996 Jan; 24(1):126-36. PubMed ID: 8825200
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of human cytochrome P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450.
    Zhao XJ; Yokoyama H; Chiba K; Wanwimolruk S; Ishizaki T
    J Pharmacol Exp Ther; 1996 Dec; 279(3):1327-34. PubMed ID: 8968357
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolism of taxol by human hepatic microsomes and liver slices: participation of cytochrome P450 3A4 and an unknown P450 enzyme.
    Harris JW; Rahman A; Kim BR; Guengerich FP; Collins JM
    Cancer Res; 1994 Aug; 54(15):4026-35. PubMed ID: 7913410
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hepatic drug clearance in patients with mild cystic fibrosis.
    Kearns GL; Crom WR; Karlson KH; Mallory GB; Evans WE
    Clin Pharmacol Ther; 1996 May; 59(5):529-40. PubMed ID: 8646824
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Simultaneous determination of antipyrine, 4-hydroxyantipyrine, 3-hydroxymethylantipyrine and norantipyrine in urine by gas chromatography chemical ionization mass spectrometry.
    Tang BK; Uchino H; Inaba T; Kalow W
    Biomed Mass Spectrom; 1982 Oct; 9(10):425-8. PubMed ID: 7171741
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multiple cytochrome P-450s involved in the metabolism of terbinafine suggest a limited potential for drug-drug interactions.
    Vickers AE; Sinclair JR; Zollinger M; Heitz F; Glänzel U; Johanson L; Fischer V
    Drug Metab Dispos; 1999 Sep; 27(9):1029-38. PubMed ID: 10460803
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac.
    Tang W; Stearns RA; Wang RW; Chiu SH; Baillie TA
    Chem Res Toxicol; 1999 Feb; 12(2):192-9. PubMed ID: 10027798
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of human cytochrome P450 enzymes involved in the metabolism of cyamemazine.
    Arbus C; Benyamina A; Llorca PM; Baylé F; Bromet N; Massiere F; Garay RP; Hameg A
    Eur J Pharm Sci; 2007 Dec; 32(4-5):357-66. PubMed ID: 17951033
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human CYP2C19 is a major omeprazole 5-hydroxylase, as demonstrated with recombinant cytochrome P450 enzymes.
    Karam WG; Goldstein JA; Lasker JM; Ghanayem BI
    Drug Metab Dispos; 1996 Oct; 24(10):1081-7. PubMed ID: 8894508
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A predominate role of CYP1A2 for the metabolism of nabumetone to the active metabolite, 6-methoxy-2-naphthylacetic acid, in human liver microsomes.
    Turpeinen M; Hofmann U; Klein K; Mürdter T; Schwab M; Zanger UM
    Drug Metab Dispos; 2009 May; 37(5):1017-24. PubMed ID: 19204080
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of human hepatic cytochrome p450 enzymes involved in the biotransformation of cholic and chenodeoxycholic acid.
    Deo AK; Bandiera SM
    Drug Metab Dispos; 2008 Oct; 36(10):1983-91. PubMed ID: 18583509
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.