325 related articles for article (PubMed ID: 8691472)
1. Acyl-CoA:Cholesterol O-acyltransferase (ACAT) inhibitors. 2. 2-(1,3-Dioxan-2-yl)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT.
Astles PC; Ashton MJ; Bridge AW; Harris NV; Hart TW; Parrott DP; Porter B; Riddell D; Smith C; Williams RJ
J Med Chem; 1996 Mar; 39(7):1423-32. PubMed ID: 8691472
[TBL] [Abstract][Full Text] [Related]
2. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. synthesis and pharmacological activity of (+/-)-2-dodecyl-alpha-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-5- acetamide and structurally related tetrazole amide derivatives.
O'Brien PM; Sliskovic DR; Picard JA; Lee HT; Purchase CF; Roth BD; White AD; Anderson M; Mueller SB; Bocan T; Bousley R; Hamelehle KL; Homan R; Lee P; Krause BR; Reindel JF; Stanfield RL; Turluck D
J Med Chem; 1996 Jun; 39(12):2354-66. PubMed ID: 8691430
[TBL] [Abstract][Full Text] [Related]
3. Inhibitors of acyl CoA:cholesterol acyltransferase.
Vaccaro W; Amore C; Berger J; Burrier R; Clader J; Davis H; Domalski M; Fevig T; Salisbury B; Sher R
J Med Chem; 1996 Apr; 39(8):1704-19. PubMed ID: 8648610
[TBL] [Abstract][Full Text] [Related]
4. Potent inhibitors of acyl-CoA:cholesterol acyltransferase. 2. Structure-activity relationships of novel N-(2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)amides.
Kataoka K; Shiota T; Takeyasu T; Minoshima T; Watanabe K; Tanaka H; Mochizuki T; Taneda K; Ota M; Tanabe H; Yamaguchi H
J Med Chem; 1996 Mar; 39(6):1262-70. PubMed ID: 8632433
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of novel 4,5-diphenylthiazole derivatives as potential acyl-CoA:cholesterol O-acyltransferase inhibitors.
Romeo G; Salerno L; Milla P; Siracusa M; Cattel L; Russo F
Pharmazie; 1999 Jan; 54(1):19-23. PubMed ID: 9987793
[TBL] [Abstract][Full Text] [Related]
6. Heterocyclic amides: inhibitors of acyl-CoA:cholesterol O-acyl transferase with hypocholesterolemic activity in several species and antiatherosclerotic activity in the rabbit.
White AD; Purchase CF; Picard JA; Anderson MK; Mueller SB; Bocan TM; Bousley RF; Hamelehle KL; Krause BR; Lee P; Stanfield RL; Reindel JF
J Med Chem; 1996 Sep; 39(20):3908-19. PubMed ID: 8831757
[TBL] [Abstract][Full Text] [Related]
7. Acyl-CoA:cholesterol O-acyl transferase (ACAT) inhibitors. 1. 2-(Alkylthio)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT.
Harris NV; Smith C; Ashton MJ; Bridge AW; Bush RC; Coffee EC; Dron DI; Harper MF; Lythgoe DJ; Newton CG
J Med Chem; 1992 Nov; 35(23):4384-92. PubMed ID: 1447739
[TBL] [Abstract][Full Text] [Related]
8. Relationships between lipophilicity and biological activities in a series of indoline-based anti-oxidative acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors.
Takahashi K; Kunishiro K; Kasai M; Miike T; Kurahashi K; Shirahase H
Arzneimittelforschung; 2008; 58(12):666-72. PubMed ID: 19202739
[TBL] [Abstract][Full Text] [Related]
9. Acyl CoA:cholesterol acyltransferase (ACAT) inhibitors: synthesis and structure-activity relationship studies of a new series of trisubstituted imidazoles.
Higley CA; Wilde RG; Maduskuie TP; Johnson AL; Pennev P; Billheimer JT; Robinson CS; Gillies PJ; Wexler RR
J Med Chem; 1994 Oct; 37(21):3511-22. PubMed ID: 7932580
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and structure-activity relationship studies on a novel series of naphthylidinoylureas as inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT).
Ohnuma S; Muraoka M; Ioriya K; Ohashi N
Bioorg Med Chem Lett; 2004 Mar; 14(5):1309-11. PubMed ID: 14980688
[TBL] [Abstract][Full Text] [Related]
11. Hypolipidemic and antioxidant activity of the novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor KY-455 in rabbits and hamsters.
Nakamura S; Kamiya S; Shirahase H; Kanda M; Yoshimi A; Tarumi T; Kurahashi K
Arzneimittelforschung; 2004; 54(2):102-8. PubMed ID: 15038459
[TBL] [Abstract][Full Text] [Related]
12. Studies on acyl-CoA: cholesterol acyltransferase (ACAT) inhibitory effects and enzyme selectivity of F-1394, a pantotheic acid derivative.
Kusunoki J; Aragane K; Yamaura T; Ohnishi H
Jpn J Pharmacol; 1995 Mar; 67(3):195-203. PubMed ID: 7630037
[TBL] [Abstract][Full Text] [Related]
13. Structure-activity relationship of a series of phenylureas linked to 4-phenylimidazole. Novel potent inhibitors of acyl-CoA:cholesterol O-acyltransferase with antiatherosclerotic activity. 2.
Kimura T; Watanabe N; Matsui M; Hayashi K; Tanaka H; Ohtsuka I; Saeki T; Kogushi M; Kabayashi H; Akasaka K
J Med Chem; 1993 May; 36(11):1641-53. PubMed ID: 8496931
[TBL] [Abstract][Full Text] [Related]
14. Hypolipidaemic properties of a potent and bioavailable alkylsulphinyl-diphenylimidazole ACAT inhibitor (RP 73163) in animals fed diets low in cholesterol.
Riddell D; Bright CP; Burton BJ; Bush RC; Harris NV; Hele D; Moore UM; Naik K; Parrott DP; Smith C; Williams RJ
Biochem Pharmacol; 1996 Oct; 52(8):1177-86. PubMed ID: 8937424
[TBL] [Abstract][Full Text] [Related]
15. Quantitative structure-activity relationship of 4,5-diphenyl-2-(substituted thio)-1H-imidazoles as the inhibitors of acyl CoA: cholesterol acyltransferase.
Singh P; Kumar R
Indian J Biochem Biophys; 1998 Jun; 35(3):179-83. PubMed ID: 9803668
[TBL] [Abstract][Full Text] [Related]
16. Acyl-coenzyme A:cholesterol acyltransferase inhibitors for controlling hypercholesterolemia and atherosclerosis.
Miyazaki A; Sakai M; Sakamoto Y; Horiuchi S
Curr Opin Investig Drugs; 2003 Sep; 4(9):1095-9. PubMed ID: 14582454
[TBL] [Abstract][Full Text] [Related]
17. alpha-Substituted malonester amides: tools to define the relationship between ACAT inhibition and adrenal toxicity.
Sliskovic DR; Picard JA; O'Brien PM; Liao P; Roark WH; Roth BD; Anderson MA; Mueller SB; Bocan TM; Bousley RF; Hamelehle KL; Homan R; Reindel JF; Stanfield RL; Turluck D; Krause BR
J Med Chem; 1998 Feb; 41(5):682-90. PubMed ID: 9513596
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis, and structure--activity relationship studies for a new imidazole series of J774 macrophage specific acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors.
Maduskuie TP; Wilde RG; Billheimer JT; Cromley DA; Germain S; Gillies PJ; Higley CA; Johnson AL; Pennev P; Shimshick EJ
J Med Chem; 1995 Mar; 38(7):1067-83. PubMed ID: 7707310
[TBL] [Abstract][Full Text] [Related]
19. Acyl-CoA : cholesterol acyltransferase inhibitors from Magnolia obovata.
Kwon BM; Kim MK; Lee SH; Kim JA; Lee IR; Kim YK; Bok SH
Planta Med; 1997 Dec; 63(6):550-1. PubMed ID: 9434609
[TBL] [Abstract][Full Text] [Related]
20. Imidazolylbenzopyrane derivatives: a new class of acyl-CoA: cholesterol acyltransferase (ACAT) inhibitors.
Fancelli D; Chiari A; Cozzi P; Lovisolo P; Severino D; Ghiselli G
J Enzyme Inhib; 1994; 8(3):159-72. PubMed ID: 7539485
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]