112 related articles for article (PubMed ID: 8691988)
1. Characterization of the oxidation reactions catalyzed by CYP2D enzyme in rat renal microsomes.
Masubuchi Y; Yamamoto K; Suzuki T; Horie T; Narimatsu S
Life Sci; 1996 May; 58(26):2431-7. PubMed ID: 8691988
[TBL] [Abstract][Full Text] [Related]
2. Selective deficiency of debrisoquine 4-hydroxylase activity in mouse liver microsomes.
Masubuchi Y; Iwasa T; Hosokawa S; Suzuki T; Horie T; Imaoka S; Funae Y; Narimatsu S
J Pharmacol Exp Ther; 1997 Sep; 282(3):1435-41. PubMed ID: 9316857
[TBL] [Abstract][Full Text] [Related]
3. An evaluation of cytochrome P450 isoform activities in the female dark agouti (DA) rat: relevance to its use as a model of the CYP2D6 poor metaboliser phenotype.
Barham HM; Lennard MS; Tucker GT
Biochem Pharmacol; 1994 Apr; 47(8):1295-307. PubMed ID: 8185638
[TBL] [Abstract][Full Text] [Related]
4. Catalytic specificity of CYP2D isoforms in rat and human.
Hiroi T; Chow T; Imaoka S; Funae Y
Drug Metab Dispos; 2002 Sep; 30(9):970-6. PubMed ID: 12167561
[TBL] [Abstract][Full Text] [Related]
5. Involvement of a cytochrome P4502D subfamily in human liver microsomal bunitrolol 4-hydroxylation.
Narimatsu S; Masubuchi Y; Hosokawa S; Ohmori S; Kitada M; Suzuki T
Biol Pharm Bull; 1994 Jun; 17(6):803-7. PubMed ID: 7951142
[TBL] [Abstract][Full Text] [Related]
6. Purification and characterization of a dog cytochrome P450 isozyme belonging to the CYP2D subfamily and development of its antipeptide antibody.
Nakamura A; Yamamoto Y; Tasaki T; Sugimoto C; Masuda M; Kazusaka A; Fujita S
Drug Metab Dispos; 1995 Nov; 23(11):1268-73. PubMed ID: 8591729
[TBL] [Abstract][Full Text] [Related]
7. In vivo administration of H2 blockers, cimetidine and ranitidine, reduced the contents of the cytochrome P450IID (CYP2D) subfamily and their activities in rat liver microsomes.
Orishiki M; Matsuo Y; Nishioka M; Ichikawa Y
Int J Biochem; 1994 Jun; 26(6):751-8. PubMed ID: 8063004
[TBL] [Abstract][Full Text] [Related]
8. Imipramine-induced inactivation of a cytochrome P450 2D enzyme in rat liver microsomes: in relation to covalent binding of its reactive intermediate.
Masubuchi Y; Igarashi S; Suzuki T; Horie T; Narimatsu S
J Pharmacol Exp Ther; 1996 Nov; 279(2):724-31. PubMed ID: 8930177
[TBL] [Abstract][Full Text] [Related]
9. Cytochrome P450 isozymes involved in propranolol metabolism in human liver microsomes. The role of CYP2D6 as ring-hydroxylase and CYP1A2 as N-desisopropylase.
Masubuchi Y; Hosokawa S; Horie T; Suzuki T; Ohmori S; Kitada M; Narimatsu S
Drug Metab Dispos; 1994; 22(6):909-15. PubMed ID: 7895609
[TBL] [Abstract][Full Text] [Related]
10. Polymorphic debrisoquine 4-hydroxylase activity in the rat is due to differences in CYP2D2 expression.
Schulz-Utermoehl T; Bennett AJ; Ellis SW; Tucker GT; Boobis AR; Edwards RJ
Pharmacogenetics; 1999 Jun; 9(3):357-66. PubMed ID: 10471068
[TBL] [Abstract][Full Text] [Related]
11. Inhibition and induction of cytochrome P450 isozymes after repetitive administration of imipramine in rats.
Masubuchi Y; Takahashii C; Fujio N; Horie T; Suzuki T; Imaoka S; Funae Y; Narimatsu S
Drug Metab Dispos; 1995 Sep; 23(9):999-1003. PubMed ID: 8565792
[TBL] [Abstract][Full Text] [Related]
12. Regioselectivity and substrate concentration-dependency of involvement of the CYP2D subfamily in oxidative metabolism of amitriptyline and nortriptyline in rat liver microsomes.
Masubuchi Y; Iwasa T; Fujita S; Suzuki T; Horie T; Narimatsu S
J Pharm Pharmacol; 1996 Sep; 48(9):925-9. PubMed ID: 9036183
[TBL] [Abstract][Full Text] [Related]
13. In-vitro metabolic interaction of bunitrolol enantiomers in rabbit liver microsomes.
Narimatsu S; Mizukami T; Huang Y; Masubuchi Y; Suzuki T
J Pharm Pharmacol; 1996 Nov; 48(11):1185-9. PubMed ID: 8961170
[TBL] [Abstract][Full Text] [Related]
14. Inactivation of rat cytochrome P450 2D enzyme by a further metabolite of 4-hydroxypropranolol, the major and active metabolite of propranolol.
Narimatsu S; Arai T; Masubuchi Y; Horie T; Hosokawa M; Ueno K; Kataoka H; Yamamoto S; Ishikawa T; Cho AK
Biol Pharm Bull; 2001 Sep; 24(9):988-94. PubMed ID: 11558582
[TBL] [Abstract][Full Text] [Related]
15. In vitro evidence against the oxidation of quinidine by the sparteine/debrisoquine monooxygenase of human liver.
Otton SV; Brinn RU; Gram LF
Drug Metab Dispos; 1988; 16(1):15-7. PubMed ID: 2894945
[TBL] [Abstract][Full Text] [Related]
16. Molecular basis of the Dark Agouti rat drug oxidation polymorphism: importance of CYP2D1 and CYP2D2.
Yamamoto Y; Tasaki T; Nakamura A; Iwata H; Kazusaka A; Gonzalez FJ; Fujita S
Pharmacogenetics; 1998 Feb; 8(1):73-82. PubMed ID: 9511184
[TBL] [Abstract][Full Text] [Related]
17. Purification and characterization of a cytochrome P-450 isozyme catalyzing bunitrolol 4-hydroxylation in liver microsomes of male rats.
Suzuki T; Narimatsu S; Fujita S; Masubuchi Y; Umeda S; Imaoka S; Funae Y
Drug Metab Dispos; 1992; 20(3):367-73. PubMed ID: 1355709
[TBL] [Abstract][Full Text] [Related]
18. The specificity of inhibition of debrisoquine 4-hydroxylase activity by quinidine and quinine in the rat is the inverse of that in man.
Kobayashi S; Murray S; Watson D; Sesardic D; Davies DS; Boobis AR
Biochem Pharmacol; 1989 Sep; 38(17):2795-9. PubMed ID: 2775304
[TBL] [Abstract][Full Text] [Related]
19. Development of a high-performance liquid chromatographic method for the analysis of enatiomer/enantiomer interaction in oxidative metabolism of bunitrolol in rat liver microsomes.
Narimatsu S; Huang Y; Mizukami T; Masubuchi Y; Suzuki T
Anal Biochem; 1994 Oct; 222(1):256-61. PubMed ID: 7856858
[TBL] [Abstract][Full Text] [Related]
20. Cytochrome P450 isozymes catalyzing 4-hydroxylation of parkinsonism-related compound 1,2,3,4-tetrahydroisoquinoline in rat liver microsomes.
Suzuki T; Fujita S; Narimatsu S; Masubuchi Y; Tachibana M; Ohta S; Hirobe M
FASEB J; 1992 Jan; 6(2):771-6. PubMed ID: 1537468
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]