BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 8697449)

  • 1. Effects of inhibitors of deoxyhypusine synthase on the differentiation of mouse neuroblastoma and erythroleukemia cells.
    Chen ZP; Yan YP; Ding QJ; Knapp S; Potenza JA; Schugar HJ; Chen KY
    Cancer Lett; 1996 Aug; 105(2):233-9. PubMed ID: 8697449
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aminohexanoic hydroxamate is a potent inducer of the differentiation of mouse neuroblastoma cells.
    Lu J; Chen ZP; Yan YP; Knapp S; Schugar H; Chen KY
    Cancer Lett; 2000 Nov; 160(1):59-66. PubMed ID: 11098085
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.
    Schultz CR; Geerts D; Mooney M; El-Khawaja R; Koster J; Bachmann AS
    Biochem J; 2018 Jan; 475(2):531-545. PubMed ID: 29295892
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on the growth of tumorigenic cell lines in culture.
    Shi XP; Yin KC; Ahern J; Davis LJ; Stern AM; Waxman L
    Biochim Biophys Acta; 1996 Jan; 1310(1):119-26. PubMed ID: 9244184
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on endothelial cell growth, differentiation and apoptosis.
    Lee Y; Kim HK; Park HE; Park MH; Joe YA
    Mol Cell Biochem; 2002 Aug; 237(1-2):69-76. PubMed ID: 12236588
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antiproliferative effects of inhibitors of deoxyhypusine synthase. Inhibition of growth of Chinese hamster ovary cells by guanyl diamines.
    Park MH; Wolff EC; Lee YB; Folk JE
    J Biol Chem; 1994 Nov; 269(45):27827-32. PubMed ID: 7961711
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients.
    Bandino A; Geerts D; Koster J; Bachmann AS
    Cell Oncol (Dordr); 2014 Dec; 37(6):387-98. PubMed ID: 25315710
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of hypusine depletion in cytostasis induced by S-adenosyl-L-methionine decarboxylase inhibition: new evidence provided by 1-methylspermidine and 1,12-dimethylspermine.
    Byers TL; Lakanen JR; Coward JK; Pegg AE
    Biochem J; 1994 Oct; 303 ( Pt 2)(Pt 2):363-8. PubMed ID: 7980394
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dramatic attenuation of hypusine formation on eukaryotic initiation factor 5A during senescence of IMR-90 human diploid fibroblasts.
    Chen ZP; Chen KY
    J Cell Physiol; 1997 Mar; 170(3):248-54. PubMed ID: 9066781
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Marked elevation of hypusine formation activity on eukaryotic initiation factor 5A in v-HA-RAS transformed mouse NIH3T3 cells.
    Chen ZP; Chen KY
    Cancer Lett; 1997 May; 115(2):235-41. PubMed ID: 9149130
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N(1)-guanyl-1,7,-diamineoheptane, an inhibitor of deoxyhypusine synthase, suppresses differentiation and induces apoptosis via mitochondrial and AMPK pathways in immortalized and malignant human oral keratinocytes.
    Lee SK; Lee J; Lee SI; Bae WJ; Lee YM; Park JS; Lee SK; Park SJ; Min SK; Kim EC
    J Oral Pathol Med; 2009 Nov; 38(10):792-800. PubMed ID: 19656269
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Independent roles of eIF5A and polyamines in cell proliferation.
    Nishimura K; Murozumi K; Shirahata A; Park MH; Kashiwagi K; Igarashi K
    Biochem J; 2005 Feb; 385(Pt 3):779-85. PubMed ID: 15377278
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Diamine and triamine analogs and derivatives as inhibitors of deoxyhypusine synthase: synthesis and biological activity.
    Lee YB; Park MH; Folk JE
    J Med Chem; 1995 Aug; 38(16):3053-61. PubMed ID: 7636868
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.
    Preukschas M; Hagel C; Schulte A; Weber K; Lamszus K; Sievert H; Pällmann N; Bokemeyer C; Hauber J; Braig M; Balabanov S
    PLoS One; 2012; 7(8):e43468. PubMed ID: 22927971
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Deoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetes.
    Colvin SC; Maier B; Morris DL; Tersey SA; Mirmira RG
    J Biol Chem; 2013 Dec; 288(51):36226-35. PubMed ID: 24196968
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Deoxyhypusine synthase assay based on the use of polyhistidine-tagged substrate and metal chelate-affinity chromatography.
    Tao Y; Skrenta HM; Chen KY
    Anal Biochem; 1994 Aug; 221(1):103-8. PubMed ID: 7985780
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Branched-chain and unsaturated 1,7-diaminoheptane derivatives as deoxyhypusine synthase inhibitors.
    Lee YB; Folk JE
    Bioorg Med Chem; 1998 Mar; 6(3):253-70. PubMed ID: 9568280
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A new non-radioactive deoxyhypusine synthase assay adaptable to high throughput screening.
    Park MH; Mandal A; Mandal S; Wolff EC
    Amino Acids; 2017 Nov; 49(11):1793-1804. PubMed ID: 28819816
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Complex formation between deoxyhypusine synthase and its protein substrate, the eukaryotic translation initiation factor 5A (eIF5A) precursor.
    Lee YB; Joe YA; Wolff EC; Dimitriadis EK; Park MH
    Biochem J; 1999 May; 340 ( Pt 1)(Pt 1):273-81. PubMed ID: 10229683
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytostasis induced in L1210 murine leukaemia cells by the S-adenosyl-L-methionine decarboxylase inhibitor 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine may be due to hypusine depletion.
    Byers TL; Ganem B; Pegg AE
    Biochem J; 1992 Nov; 287 ( Pt 3)(Pt 3):717-24. PubMed ID: 1445235
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.