These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
177 related articles for article (PubMed ID: 8699174)
1. The iron environment in heme and heme-antimalarial complexes of pharmacological interest. Adams PA; Berman PA; Egan TJ; Marsh PJ; Silver J J Inorg Biochem; 1996 Jul; 63(1):69-77. PubMed ID: 8699174 [TBL] [Abstract][Full Text] [Related]
2. Considerations on the mechanism of action of artemisinin antimalarials: part 1--the 'carbon radical' and 'heme' hypotheses. Haynes RK; Cheu KW; N'Da D; Coghi P; Monti D Infect Disord Drug Targets; 2013 Aug; 13(4):217-77. PubMed ID: 24304352 [TBL] [Abstract][Full Text] [Related]
3. The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex. Alumasa JN; Gorka AP; Casabianca LB; Comstock E; de Dios AC; Roepe PD J Inorg Biochem; 2011 Mar; 105(3):467-75. PubMed ID: 20864177 [TBL] [Abstract][Full Text] [Related]
4. Trioxaquines and heme-artemisinin adducts inhibit the in vitro formation of hemozoin better than chloroquine. Loup C; Lelièvre J; Benoit-Vical F; Meunier B Antimicrob Agents Chemother; 2007 Oct; 51(10):3768-70. PubMed ID: 17698628 [TBL] [Abstract][Full Text] [Related]
5. Interactions between artemisinins and other antimalarial drugs in relation to the cofactor model--a unifying proposal for drug action. Haynes RK; Cheu KW; Chan HW; Wong HN; Li KY; Tang MM; Chen MJ; Guo ZF; Guo ZH; Sinniah K; Witte AB; Coghi P; Monti D ChemMedChem; 2012 Dec; 7(12):2204-26. PubMed ID: 23112085 [TBL] [Abstract][Full Text] [Related]
6. A novel endogenous antimalarial: Fe(II)-protoporphyrin IX alpha (heme) inhibits hematin polymerization to beta-hematin (malaria pigment) and kills malaria parasites. Monti D; Vodopivec B; Basilico N; Olliaro P; Taramelli D Biochemistry; 1999 Jul; 38(28):8858-63. PubMed ID: 10413458 [TBL] [Abstract][Full Text] [Related]
7. Ferryl-oxo heme intermediate in the antimalarial mode of action of artemisinin. Kapetanaki S; Varotsis C FEBS Lett; 2000 Jun; 474(2-3):238-41. PubMed ID: 10838092 [TBL] [Abstract][Full Text] [Related]
8. Toward understanding the chloroquine action at the molecular level in antimalarial therapy--X-ray absorption studies in acetic acid solution. Walczak MS; Lawniczak-Jablonska K; Wolska A; Sikora M; Sienkiewicz A; Suárez L; Kosar AJ; Bellemare MJ; Bohle DS J Phys Chem B; 2011 Apr; 115(15):4419-26. PubMed ID: 21434658 [TBL] [Abstract][Full Text] [Related]
9. Antimalarials inhibit hematin crystallization by unique drug-surface site interactions. Olafson KN; Nguyen TQ; Rimer JD; Vekilov PG Proc Natl Acad Sci U S A; 2017 Jul; 114(29):7531-7536. PubMed ID: 28559329 [TBL] [Abstract][Full Text] [Related]
10. Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs. Fitch CD Life Sci; 2004 Mar; 74(16):1957-72. PubMed ID: 14967191 [TBL] [Abstract][Full Text] [Related]
12. Evidence that haem iron in the malaria parasite is not needed for the antimalarial effects of artemisinin. Parapini S; Basilico N; Mondani M; Olliaro P; Taramelli D; Monti D FEBS Lett; 2004 Sep; 575(1-3):91-4. PubMed ID: 15388339 [TBL] [Abstract][Full Text] [Related]
13. Characterization of noncovalent complexes of antimalarial agents of the artemisinin-type and FE(III)-heme by electrospray mass spectrometry and collisional activation tandem mass spectrometry. Pashynska VA; Van den Heuvel H; Claeys M; Kosevich MV J Am Soc Mass Spectrom; 2004 Aug; 15(8):1181-90. PubMed ID: 15276165 [TBL] [Abstract][Full Text] [Related]
15. [In vitro susceptibility of P. falciparum isolates from Abidjan (Côte d'Ivoire) to quinine, artesunate and chloroquine]. Touré AO; Koné LP; Jambou R; Konan TD; Demba S; Beugre GE; Koné M Sante; 2008; 18(1):43-7. PubMed ID: 18684691 [TBL] [Abstract][Full Text] [Related]
16. Reaction between ferriprotoporphyrin IX and the antimalarial endoperoxide artesunate gives an intermediate species with enhanced redox catalytic activity. Adams PA; Berman PA J Pharm Pharmacol; 1996 Feb; 48(2):183-7. PubMed ID: 8935168 [TBL] [Abstract][Full Text] [Related]
17. Monocyte phagocytosis of malaria β-haematin in the presence of artemisinin, amodiaquine, chloroquine, doxycycline, primaquine, pyrimethamine and quinine. Cumming BM; Goldring JPD Exp Parasitol; 2019 Feb; 197():93-102. PubMed ID: 30562480 [TBL] [Abstract][Full Text] [Related]
18. The chemical basis for the ferriprotoporphyrin IX-chloroquine complex induced lipid peroxidation. Sugioka Y; Suzuki M Biochim Biophys Acta; 1991 May; 1074(1):19-24. PubMed ID: 2043670 [TBL] [Abstract][Full Text] [Related]
19. Targeting the hemozoin synthesis pathway for new antimalarial drug discovery: technologies for in vitro beta-hematin formation assay. Tekwani BL; Walker LA Comb Chem High Throughput Screen; 2005 Feb; 8(1):63-79. PubMed ID: 15720198 [TBL] [Abstract][Full Text] [Related]
20. Involvement of heme in the antimalarial action of chloroquine. Fitch CD Trans Am Clin Climatol Assoc; 1998; 109():97-105; discussion 105-6. PubMed ID: 9601131 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]