BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 8703430)

  • 1. Mutants blocked in penicillin biosynthesis show a deletion of the entire penicillin gene cluster at a specific site within a conserved hexanucleotide sequence.
    Fierro F; Montenegro E; Gutiérrez S; Martín JF
    Appl Microbiol Biotechnol; 1996 Jan; 44(5):597-604. PubMed ID: 8703430
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biochemical characterization and molecular genetics of nine mutants of Penicillium chrysogenum impaired in penicillin biosynthesis.
    Cantoral JM; Gutiérrez S; Fierro F; Gil-Espinosa S; van Liempt H; Martín JF
    J Biol Chem; 1993 Jan; 268(1):737-44. PubMed ID: 8416976
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transcriptional and bioinformatic analysis of the 56.8 kb DNA region amplified in tandem repeats containing the penicillin gene cluster in Penicillium chrysogenum.
    Fierro F; García-Estrada C; Castillo NI; Rodríguez R; Velasco-Conde T; Martín JF
    Fungal Genet Biol; 2006 Sep; 43(9):618-29. PubMed ID: 16713314
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The penicillin gene cluster is amplified in tandem repeats linked by conserved hexanucleotide sequences.
    Fierro F; Barredo JL; Díez B; Gutierrez S; Fernández FJ; Martín JF
    Proc Natl Acad Sci U S A; 1995 Jun; 92(13):6200-4. PubMed ID: 7597101
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The cluster of penicillin biosynthetic genes. Identification and characterization of the pcbAB gene encoding the alpha-aminoadipyl-cysteinyl-valine synthetase and linkage to the pcbC and penDE genes.
    Díez B; Gutiérrez S; Barredo JL; van Solingen P; van der Voort LH; Martín JF
    J Biol Chem; 1990 Sep; 265(27):16358-65. PubMed ID: 2129535
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Expression of genes and processing of enzymes for the biosynthesis of penicillins and cephalosporins.
    Martín JF; Gutiérrez S; Fernández FJ; Velasco J; Fierro F; Marcos AT; Kosalkova K
    Antonie Van Leeuwenhoek; 1994; 65(3):227-43. PubMed ID: 7847890
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular characterization of three loss-of-function mutations in the isopenicillin N-acyltransferase gene (penDE) of Penicillium chrysogenum.
    Fernández FJ; Gutierrez S; Velasco J; Montenegro E; Marcos AT; Martín JF
    J Bacteriol; 1994 Aug; 176(16):4941-8. PubMed ID: 7519594
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of a Penicillium chrysogenum gene encoding a PacC transcription factor and its binding sites in the divergent pcbAB-pcbC promoter of the penicillin biosynthetic cluster.
    Suárez T; Peñalva MA
    Mol Microbiol; 1996 May; 20(3):529-40. PubMed ID: 8736532
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional characterization of the penicillin biosynthetic gene cluster of Penicillium chrysogenum Wisconsin54-1255.
    van den Berg MA; Westerlaken I; Leeflang C; Kerkman R; Bovenberg RA
    Fungal Genet Biol; 2007 Sep; 44(9):830-44. PubMed ID: 17548217
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The global regulator LaeA controls penicillin biosynthesis, pigmentation and sporulation, but not roquefortine C synthesis in Penicillium chrysogenum.
    Kosalková K; García-Estrada C; Ullán RV; Godio RP; Feltrer R; Teijeira F; Mauriz E; Martín JF
    Biochimie; 2009 Feb; 91(2):214-25. PubMed ID: 18952140
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nonlinear biosynthetic gene cluster dose effect on penicillin production by Penicillium chrysogenum.
    Nijland JG; Ebbendorf B; Woszczynska M; Boer R; Bovenberg RA; Driessen AJ
    Appl Environ Microbiol; 2010 Nov; 76(21):7109-15. PubMed ID: 20851974
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two genes involved in penicillin biosynthesis are linked in a 5.1 kb SalI fragment in the genome of Penicillium chrysogenum.
    Díez B; Barredo JL; Alvarez E; Cantoral JM; van Solingen P; Groenen MA; Veenstra AE; Martín JF
    Mol Gen Genet; 1989 Sep; 218(3):572-6. PubMed ID: 2511425
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Penicillin production in industrial strain Penicillium chrysogenum P2niaD18 is not dependent on the copy number of biosynthesis genes.
    Ziemons S; Koutsantas K; Becker K; Dahlmann T; Kück U
    BMC Biotechnol; 2017 Feb; 17(1):16. PubMed ID: 28209150
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quantitative analysis of Penicillium chrysogenum Wis54-1255 transformants overexpressing the penicillin biosynthetic genes.
    Theilgaard H; van Den Berg M; Mulder C; Bovenberg R; Nielsen J
    Biotechnol Bioeng; 2001 Feb; 72(4):379-88. PubMed ID: 11180058
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Large amplification of a 35-kb DNA fragment carrying two penicillin biosynthetic genes in high penicillin producing strains of Penicillium chrysogenum.
    Barredo JL; Díez B; Alvarez E; Martín JF
    Curr Genet; 1989 Dec; 16(5-6):453-9. PubMed ID: 2515004
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The isopenicillin-N acyltransferase of Penicillium chrysogenum has isopenicillin-N amidohydrolase, 6-aminopenicillanic acid acyltransferase and penicillin amidase activities, all of which are encoded by the single penDE gene.
    Alvarez E; Meesschaert B; Montenegro E; Gutiérrez S; Díez B; Barredo JL; Martín JF
    Eur J Biochem; 1993 Jul; 215(2):323-32. PubMed ID: 8344300
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Organization of the gene cluster for biosynthesis of penicillin in Penicillium nalgiovense and antibiotic production in cured dry sausages.
    Laich F; Fierro F; Cardoza RE; Martin JF
    Appl Environ Microbiol; 1999 Mar; 65(3):1236-40. PubMed ID: 10049889
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel heptameric sequence (TTAGTAA) is the binding site for a protein required for high level expression of pcbAB, the first gene of the penicillin biosynthesis in Penicillium chrysogenum.
    Kosalková K; Marcos AT; Fierro F; Hernando-Rico V; Gutiérrez S; Martín JF
    J Biol Chem; 2000 Jan; 275(4):2423-30. PubMed ID: 10644695
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Resolution of four large chromosomes in penicillin-producing filamentous fungi: the penicillin gene cluster is located on chromosome II (9.6 Mb) in Penicillium notatum and chromosome I (10.4 Mb) in Penicillium chrysogenum.
    Fierro F; Gutiérrez S; Díez B; Martín JF
    Mol Gen Genet; 1993 Dec; 241(5-6):573-8. PubMed ID: 8264531
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular characterization of a fungal gene paralogue of the penicillin penDE gene of Penicillium chrysogenum.
    García-Estrada C; Vaca I; Ullán RV; van den Berg MA; Bovenberg RA; Martín JF
    BMC Microbiol; 2009 May; 9():104. PubMed ID: 19470155
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.