406 related articles for article (PubMed ID: 8710841)
1. Ras-catalyzed hydrolysis of GTP: a new perspective from model studies.
Maegley KA; Admiraal SJ; Herschlag D
Proc Natl Acad Sci U S A; 1996 Aug; 93(16):8160-6. PubMed ID: 8710841
[TBL] [Abstract][Full Text] [Related]
2. Ras catalyzes GTP hydrolysis by shifting negative charges from gamma- to beta-phosphate as revealed by time-resolved FTIR difference spectroscopy.
Allin C; Gerwert K
Biochemistry; 2001 Mar; 40(10):3037-46. PubMed ID: 11258917
[TBL] [Abstract][Full Text] [Related]
3. Time-resolved FTIR studies of the GTPase reaction of H-ras p21 reveal a key role for the beta-phosphate.
Cepus V; Scheidig AJ; Goody RS; Gerwert K
Biochemistry; 1998 Jul; 37(28):10263-71. PubMed ID: 9665734
[TBL] [Abstract][Full Text] [Related]
4. GTP hydrolysis mechanisms in ras p21 and in the ras-GAP complex studied by fluorescence measurements on tryptophan mutants.
Antonny B; Chardin P; Roux M; Chabre M
Biochemistry; 1991 Aug; 30(34):8287-95. PubMed ID: 1883817
[TBL] [Abstract][Full Text] [Related]
5. Mechanistic analysis of the observed linear free energy relationships in p21ras and related systems.
Schweins T; Warshel A
Biochemistry; 1996 Nov; 35(45):14232-43. PubMed ID: 8916908
[TBL] [Abstract][Full Text] [Related]
6. Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.
Schweins T; Geyer M; Kalbitzer HR; Wittinghofer A; Warshel A
Biochemistry; 1996 Nov; 35(45):14225-31. PubMed ID: 8916907
[TBL] [Abstract][Full Text] [Related]
7. Transition state structures and the roles of catalytic residues in GAP-facilitated GTPase of Ras as elucidated by (18)O kinetic isotope effects.
Du X; Sprang SR
Biochemistry; 2009 Jun; 48(21):4538-47. PubMed ID: 19610677
[TBL] [Abstract][Full Text] [Related]
8. Molecular dynamics simulations of Gly-12-->Val mutant of p21(ras): dynamic inhibition mechanism.
Futatsugi N; Tsuda M
Biophys J; 2001 Dec; 81(6):3483-8. PubMed ID: 11721009
[TBL] [Abstract][Full Text] [Related]
9. The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.
Scheffzek K; Ahmadian MR; Kabsch W; Wiesmüller L; Lautwein A; Schmitz F; Wittinghofer A
Science; 1997 Jul; 277(5324):333-8. PubMed ID: 9219684
[TBL] [Abstract][Full Text] [Related]
10. Mechanisms of guanosine triphosphate hydrolysis by Ras and Ras-GAP proteins as rationalized by ab initio QM/MM simulations.
Grigorenko BL; Nemukhin AV; Shadrina MS; Topol IA; Burt SK
Proteins; 2007 Feb; 66(2):456-66. PubMed ID: 17094109
[TBL] [Abstract][Full Text] [Related]
11. G proteins, effectors and GAPs: structure and mechanism.
Sprang SR
Curr Opin Struct Biol; 1997 Dec; 7(6):849-56. PubMed ID: 9434906
[TBL] [Abstract][Full Text] [Related]
12. Raman difference studies of GDP and GTP binding to c-Harvey ras.
Wang JH; Xiao DG; Deng H; Webb MR; Callender R
Biochemistry; 1998 Aug; 37(31):11106-16. PubMed ID: 9693007
[TBL] [Abstract][Full Text] [Related]
13. Modeling the role of G12V and G13V Ras mutations in the Ras-GAP-catalyzed hydrolysis reaction of guanosine triphosphate.
Khrenova MG; Mironov VA; Grigorenko BL; Nemukhin AV
Biochemistry; 2014 Nov; 53(45):7093-9. PubMed ID: 25339142
[TBL] [Abstract][Full Text] [Related]
14. Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins.
Schweins T; Geyer M; Scheffzek K; Warshel A; Kalbitzer HR; Wittinghofer A
Nat Struct Biol; 1995 Jan; 2(1):36-44. PubMed ID: 7719852
[TBL] [Abstract][Full Text] [Related]
15. Ras and GTPase-activating protein (GAP) drive GTP into a precatalytic state as revealed by combining FTIR and biomolecular simulations.
Rudack T; Xia F; Schlitter J; Kötting C; Gerwert K
Proc Natl Acad Sci U S A; 2012 Sep; 109(38):15295-300. PubMed ID: 22949691
[TBL] [Abstract][Full Text] [Related]
16. Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP.
Tong LA; de Vos AM; Milburn MV; Kim SH
J Mol Biol; 1991 Feb; 217(3):503-16. PubMed ID: 1899707
[TBL] [Abstract][Full Text] [Related]
17. QM/MM modeling the Ras-GAP catalyzed hydrolysis of guanosine triphosphate.
Grigorenko BL; Nemukhin AV; Topol IA; Cachau RE; Burt SK
Proteins; 2005 Aug; 60(3):495-503. PubMed ID: 15906320
[TBL] [Abstract][Full Text] [Related]
18. Role of glutamine-61 in the hydrolysis of GTP by p21H-ras: an experimental and theoretical study.
Frech M; Darden TA; Pedersen LG; Foley CK; Charifson PS; Anderson MW; Wittinghofer A
Biochemistry; 1994 Mar; 33(11):3237-44. PubMed ID: 8136358
[TBL] [Abstract][Full Text] [Related]
19. What is the role of the helical domain of Gsalpha in the GTPase reaction?
Shnerb T; Lin N; Shurki A
Biochemistry; 2007 Sep; 46(38):10875-85. PubMed ID: 17727271
[TBL] [Abstract][Full Text] [Related]
20. The differential effects of the Gly-60 to Ala mutation on the interaction of H-Ras p21 with different downstream targets.
Hwang MC; Sung YJ; Hwang YW
J Biol Chem; 1996 Apr; 271(14):8196-202. PubMed ID: 8626511
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
