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2. Structure of porphobilinogen deaminase reveals a flexible multidomain polymerase with a single catalytic site. Louie GV; Brownlie PD; Lambert R; Cooper JB; Blundell TL; Wood SP; Warren MJ; Woodcock SC; Jordan PM Nature; 1992 Sep; 359(6390):33-9. PubMed ID: 1522882 [TBL] [Abstract][Full Text] [Related]
3. Insights into the mechanism of pyrrole polymerization catalysed by porphobilinogen deaminase: high-resolution X-ray studies of the Arabidopsis thaliana enzyme. Roberts A; Gill R; Hussey RJ; Mikolajek H; Erskine PT; Cooper JB; Wood SP; Chrystal EJ; Shoolingin-Jordan PM Acta Crystallogr D Biol Crystallogr; 2013 Mar; 69(Pt 3):471-85. PubMed ID: 23519422 [TBL] [Abstract][Full Text] [Related]
4. Structural evidence for the partially oxidized dipyrromethene and dipyrromethanone forms of the cofactor of porphobilinogen deaminase: structures of the Bacillus megaterium enzyme at near-atomic resolution. Azim N; Deery E; Warren MJ; Wolfenden BA; Erskine P; Cooper JB; Coker A; Wood SP; Akhtar M Acta Crystallogr D Biol Crystallogr; 2014 Mar; 70(Pt 3):744-51. PubMed ID: 24598743 [TBL] [Abstract][Full Text] [Related]
5. The biosynthesis of uroporphyrinogen III: mechanism of action of porphobilinogen deaminase. Jordan PM Ciba Found Symp; 1994; 180():70-89; discussion 89-96. PubMed ID: 7842863 [TBL] [Abstract][Full Text] [Related]
6. Structural studies on porphobilinogen deaminase. Lambert R; Brownlie PD; Woodcock SC; Louie GV; Cooper JC; Warren MJ; Jordan PM; Blundell TL; Wood SP Ciba Found Symp; 1994; 180():97-104; discussion 105-10. PubMed ID: 7842864 [TBL] [Abstract][Full Text] [Related]
7. Discovery that the assembly of the dipyrromethane cofactor of porphobilinogen deaminase holoenzyme proceeds initially by the reaction of preuroporphyrinogen with the apoenzyme. Shoolingin-Jordan PM; Warren MJ; Awan SJ Biochem J; 1996 Jun; 316 ( Pt 2)(Pt 2):373-6. PubMed ID: 8687374 [TBL] [Abstract][Full Text] [Related]
8. Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps. Sato H; Sugishima M; Tsukaguchi M; Masuko T; Iijima M; Takano M; Omata Y; Hirabayashi K; Wada K; Hisaeda Y; Yamamoto K Biochem J; 2021 Mar; 478(5):1023-1042. PubMed ID: 33600566 [TBL] [Abstract][Full Text] [Related]
9. Crystallization and preliminary X-ray characterization of the tetrapyrrole-biosynthetic enzyme porphobilinogen deaminase from Arabidopsis thaliana. Roberts A; Gill R; Hussey RJ; Mikolajek H; Erskine PT; Cooper JB; Wood SP; Chrystal EJ; Shoolingin-Jordan PM Acta Crystallogr Sect F Struct Biol Cryst Commun; 2012 Dec; 68(Pt 12):1491-3. PubMed ID: 23192030 [TBL] [Abstract][Full Text] [Related]
10. Structural studies of domain movement in active-site mutants of porphobilinogen deaminase from Bacillus megaterium. Guo J; Erskine P; Coker AR; Wood SP; Cooper JB Acta Crystallogr F Struct Biol Commun; 2017 Nov; 73(Pt 11):612-620. PubMed ID: 29095155 [TBL] [Abstract][Full Text] [Related]
11. Structural basis of pyrrole polymerization in human porphobilinogen deaminase. Pluta P; Roversi P; Bernardo-Seisdedos G; Rojas AL; Cooper JB; Gu S; Pickersgill RW; Millet O Biochim Biophys Acta Gen Subj; 2018 Sep; 1862(9):1948-1955. PubMed ID: 29908816 [TBL] [Abstract][Full Text] [Related]
12. Structural insight into acute intermittent porphyria. Song G; Li Y; Cheng C; Zhao Y; Gao A; Zhang R; Joachimiak A; Shaw N; Liu ZJ FASEB J; 2009 Feb; 23(2):396-404. PubMed ID: 18936296 [TBL] [Abstract][Full Text] [Related]
13. Dipyrromethane cofactor assembly of porphobilinogen deaminase: formation of apoenzyme and preparation of holoenzyme. Shoolingin-Jordan PM; Warren MJ; Awan SJ Methods Enzymol; 1997; 281():317-27. PubMed ID: 9250996 [No Abstract] [Full Text] [Related]
14. Investigation into the nature of substrate binding to the dipyrromethane cofactor of Escherichia coli porphobilinogen deaminase. Warren MJ; Jordan PM Biochemistry; 1988 Dec; 27(25):9020-30. PubMed ID: 3069132 [TBL] [Abstract][Full Text] [Related]
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16. Mutagenesis of arginine residues in the catalytic cleft of Escherichia coli porphobilinogen deaminase that affects dipyrromethane cofactor assembly and tetrapyrrole chain initiation and elongation. Jordan PM; Woodcock SC Biochem J; 1991 Dec; 280 ( Pt 2)(Pt 2):445-9. PubMed ID: 1747120 [TBL] [Abstract][Full Text] [Related]
17. Identification of a cysteine residue as the binding site for the dipyrromethane cofactor at the active site of Escherichia coli porphobilinogen deaminase. Jordan PM; Warren MJ; Williams HJ; Stolowich NJ; Roessner CA; Grant SK; Scott AI FEBS Lett; 1988 Aug; 235(1-2):189-93. PubMed ID: 3042456 [TBL] [Abstract][Full Text] [Related]
18. Crystallization and preliminary X-ray characterization of the tetrapyrrole-biosynthetic enzyme porphobilinogen deaminase from Bacillus megaterium. Azim N; Deery E; Warren MJ; Erskine P; Cooper JB; Wood SP; Akhtar M Acta Crystallogr Sect F Struct Biol Cryst Commun; 2013 Aug; 69(Pt 8):906-8. PubMed ID: 23908040 [TBL] [Abstract][Full Text] [Related]
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20. Evidence for conformational changes in Escherichia coli porphobilinogen deaminase during stepwise pyrrole chain elongation monitored by increased reactivity of cysteine-134 to alkylation by N-ethylmaleimide. Warren MJ; Gul S; Aplin RT; Scott AI; Roessner CA; O'Grady P; Shoolingin-Jordan PM Biochemistry; 1995 Sep; 34(35):11288-95. PubMed ID: 7669787 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]