BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

469 related articles for article (PubMed ID: 8728513)

  • 1. Chemical and immunochemical comparison of protein adduct formation of four carboxylate drugs in rat liver and plasma.
    Bailey MJ; Dickinson RG
    Chem Res Toxicol; 1996; 9(3):659-66. PubMed ID: 8728513
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disposition and covalent binding of diflunisal and diflunisal acyl glucuronide in the isolated perfused rat liver.
    Wang M; Dickinson RG
    Drug Metab Dispos; 1998 Feb; 26(2):98-104. PubMed ID: 9456294
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Studies on the metabolism of tolmetin to the chemically reactive acyl-coenzyme A thioester intermediate in rats.
    Olsen J; Li C; Skonberg C; Bjørnsdottir I; Sidenius U; Benet LZ; Hansen SH
    Drug Metab Dispos; 2007 May; 35(5):758-64. PubMed ID: 17303625
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of benoxaprofen and flunoxaprofen acyl glucuronides in covalent binding to rat plasma and liver proteins in vivo.
    Dong JQ; Liu J; Smith PC
    Biochem Pharmacol; 2005 Sep; 70(6):937-48. PubMed ID: 16046212
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bile duct ligation promotes covalent drug-protein adduct formation in plasma but not in liver of rats given zomepirac.
    Wang M; Dickinson RG
    Life Sci; 2000 Dec; 68(5):525-37. PubMed ID: 11197750
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dipeptidyl peptidase IV is a target for covalent adduct formation with the acyl glucuronide metabolite of the anti-inflammatory drug zomepirac.
    Wang M; Gorrell MD; McGaughan GW; Dickinson RG
    Life Sci; 2001 Jan; 68(7):785-97. PubMed ID: 11205870
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Limitations of hepatocytes and liver homogenates in modelling in vivo formation of acyl glucuronide-derived drug-protein adducts.
    Bailey MJ; Dickinson RG
    J Pharmacol Toxicol Methods; 1999 Feb; 41(1):27-32. PubMed ID: 10507755
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hepatobiliary transport of diflunisal conjugates and taurocholate by the perfused rat liver: the effect of chronic exposure of rats to diflunisal.
    Wang M; Dickinson RG
    Life Sci; 1998; 62(8):751-62. PubMed ID: 9489511
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Studies on the reactivity of acyl glucuronides--III. Glucuronide-derived adducts of valproic acid and plasma protein and anti-adduct antibodies in humans.
    Williams AM; Worrall S; de Jersey J; Dickinson RG
    Biochem Pharmacol; 1992 Feb; 43(4):745-55. PubMed ID: 1540228
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vitro and in vivo studies on acyl-coenzyme A-dependent bioactivation of zomepirac in rats.
    Olsen J; Li C; Bjørnsdottir I; Sidenius U; Hansen SH; Benet LZ
    Chem Res Toxicol; 2005 Nov; 18(11):1729-36. PubMed ID: 16300382
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Immunochemical identification of mouse hepatic protein adducts derived from the nonsteroidal anti-inflammatory drugs diclofenac, sulindac, and ibuprofen.
    Wade LT; Kenna JG; Caldwell J
    Chem Res Toxicol; 1997 May; 10(5):546-55. PubMed ID: 9168252
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Covalent binding of acidic drugs via reactive intermediates: detection of benoxaprofen and flunoxaprofen protein adducts in biological material.
    Dahms M; Spahn-Langguth H
    Pharmazie; 1996 Nov; 51(11):874-81. PubMed ID: 8985978
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reactivity of gemfibrozil 1-o-beta-acyl glucuronide. Pharmacokinetics of covalently bound gemfibrozil-protein adducts in rats.
    Sallustio BC; Foster DJ
    Drug Metab Dispos; 1995 Sep; 23(9):892-9. PubMed ID: 8565777
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats.
    Chen Q; Doss GA; Tung EC; Liu W; Tang YS; Braun MP; Didolkar V; Strauss JR; Wang RW; Stearns RA; Evans DC; Baillie TA; Tang W
    Drug Metab Dispos; 2006 Jan; 34(1):145-51. PubMed ID: 16251255
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Studies on the reactivity of acyl glucuronides--V. Glucuronide-derived covalent binding of diflunisal to bladder tissue of rats and its modulation by urinary pH and beta-glucuronidase.
    Dickinson RG; King AR
    Biochem Pharmacol; 1993 Oct; 46(7):1175-82. PubMed ID: 8216368
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of proliferation of HT-29 colon adenocarcinoma cells by carboxylate NSAIDs and their acyl glucuronides.
    Cannell GR; Vesey DA; Dickinson RG
    Life Sci; 2001 Nov; 70(1):37-48. PubMed ID: 11764005
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Zomepirac acyl glucuronide covalently modifies tubulin in vitro and in vivo and inhibits its assembly in an in vitro system.
    Bailey MJ; Worrall S; de Jersey J; Dickinson RG
    Chem Biol Interact; 1998 Sep; 115(2):153-66. PubMed ID: 9826947
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse.
    Wang M; Gorrell MD; Abbott CA; Jaggi R; Marguet D; Dickinson RG
    J Gastroenterol Hepatol; 2002 Jan; 17(1):66-71. PubMed ID: 11895555
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selective protein adducts to membrane proteins in cultured rat hepatocytes exposed to diclofenac: radiochemical and immunochemical analysis.
    Kretz-Rommel A; Boelsterli UA
    Mol Pharmacol; 1994 Feb; 45(2):237-44. PubMed ID: 8114673
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Immunochemical detection of covalently modified protein adducts in livers of rats treated with methyleugenol.
    Gardner I; Bergin P; Stening P; Kenna JG; Caldwell J
    Chem Res Toxicol; 1996 Jun; 9(4):713-21. PubMed ID: 8831815
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.