BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 8747433)

  • 21. Interaction of GTP derivatives with cellular and oncogenic ras-p21 proteins.
    Noonan T; Brown N; Dudycz L; Wright G
    J Med Chem; 1991 Apr; 34(4):1302-7. PubMed ID: 2016705
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Structural basis for conformational dynamics of GTP-bound Ras protein.
    Shima F; Ijiri Y; Muraoka S; Liao J; Ye M; Araki M; Matsumoto K; Yamamoto N; Sugimoto T; Yoshikawa Y; Kumasaka T; Yamamoto M; Tamura A; Kataoka T
    J Biol Chem; 2010 Jul; 285(29):22696-705. PubMed ID: 20479006
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Calculation of pathways for the conformational transition between the GTP- and GDP-bound states of the Ha-ras-p21 protein: calculations with explicit solvent simulations and comparison with calculations in vacuum.
    Diaz JF; Wroblowski B; Schlitter J; Engelborghs Y
    Proteins; 1997 Jul; 28(3):434-51. PubMed ID: 9223188
    [TBL] [Abstract][Full Text] [Related]  

  • 24. X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis.
    Privé GG; Milburn MV; Tong L; de Vos AM; Yamaizumi Z; Nishimura S; Kim SH
    Proc Natl Acad Sci U S A; 1992 Apr; 89(8):3649-53. PubMed ID: 1565661
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Molecular dynamics on complexes of ras-p21 and its inhibitor protein, rap-1A, bound to the ras-binding domain of the raf-p74 protein: identification of effector domains in the raf protein.
    Chen JM; Monaco R; Manolatos S; Brandt-Rauf PW; Friedman FK; Pincus MR
    J Protein Chem; 1997 Aug; 16(6):619-29. PubMed ID: 9263124
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Prediction of the three-dimensional structure of the rap-1A protein from its homology to the ras-gene-encoded p21 protein.
    Chen JM; Grad R; Monaco R; Pincus MR
    J Protein Chem; 1996 Jan; 15(1):11-5. PubMed ID: 8838585
    [TBL] [Abstract][Full Text] [Related]  

  • 27. High frequency (139.5 GHz) electron paramagnetic resonance characterization of Mn(II)-H2(17)O interactions in GDP and GTP forms of p21 ras.
    Bellew BF; Halkides CJ; Gerfen GJ; Griffin RG; Singel DJ
    Biochemistry; 1996 Sep; 35(37):12186-93. PubMed ID: 8810926
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Three-dimensional structure of p21H-ras and its implications.
    Wittinghofer F
    Semin Cancer Biol; 1992 Aug; 3(4):189-98. PubMed ID: 1421163
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Comparison of the computed structures for the phosphate-binding loop of the p21 protein containing the oncogenic site Gly 12 with the X-ray crystallographic structures for this region in the p21 protein and EFtu. A model for the structure of the p21 protein in its oncogenic form.
    Chen JM; Lee G; Murphy RB; Carty RP; Brandt-Rauf PW; Friedman E; Pincus MR
    J Biomol Struct Dyn; 1989 Apr; 6(5):859-75. PubMed ID: 2686707
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Crystal structures of the state 1 conformations of the GTP-bound H-Ras protein and its oncogenic G12V and Q61L mutants.
    Muraoka S; Shima F; Araki M; Inoue T; Yoshimoto A; Ijiri Y; Seki N; Tamura A; Kumasaka T; Yamamoto M; Kataoka T
    FEBS Lett; 2012 Jun; 586(12):1715-8. PubMed ID: 22584058
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Comparison of the predicted structures of loops in the ras-SOS protein bound to a single ras-p21 protein with the crystallographically determined structures in SOS bound to two ras-p21 proteins.
    Smith S; Hyde M; Pincus MR
    Protein J; 2005 Aug; 24(6):391-8. PubMed ID: 16323045
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Specificity of inhibition of ras-p21 signal transduction by peptides from GTPase activating protein (GAP) and the son-of sevenless (SOS) ras-specific guanine nucleotide exchange protein.
    Chie L; Chung D; Pincus MR
    Protein J; 2005 May; 24(4):253-8. PubMed ID: 16283548
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Hybrid QM/MM vs Pure MM Molecular Dynamics for Evaluating Water Distribution within p21
    Tichauer RH; Favre G; Cabantous S; Brut M
    J Phys Chem B; 2019 May; 123(18):3935-3944. PubMed ID: 30991803
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Role of glutamine-61 in the hydrolysis of GTP by p21H-ras: an experimental and theoretical study.
    Frech M; Darden TA; Pedersen LG; Foley CK; Charifson PS; Anderson MW; Wittinghofer A
    Biochemistry; 1994 Mar; 33(11):3237-44. PubMed ID: 8136358
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Activated conformations of the ras-gene-encoded p21 protein. 1. An energy-refined structure for the normal p21 protein complexed with GDP.
    Dykes DC; Brandt-Rauf P; Luster SM; Chung D; Friedman FK; Pincus MR
    J Biomol Struct Dyn; 1992 Jun; 9(6):1025-44. PubMed ID: 1637501
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Guanine-nucleotide binding activity, interaction with GTPase-activating protein and solution conformation of the human c-Ha-Ras protein catalytic domain are retained upon deletion of C-terminal 18 amino acid residues.
    Fujita-Yoshigaki J; Ito Y; Yamasaki K; Muto Y; Miyazawa T; Nishimura S; Yokoyama S
    J Protein Chem; 1992 Dec; 11(6):731-9. PubMed ID: 1466766
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Inhibition of ras-induced oocyte maturation by peptides from ras-p21 and GTPase activating protein (GAP) identified as being effector domains from molecular dynamics calculations.
    Friedman FK; Chie L; Chung D; Robinson R; Brandt-Rauf P; Yamaizumi Z; Pincus MR
    J Protein Chem; 2002 Jul; 21(5):361-6. PubMed ID: 12206510
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras.
    Franken SM; Scheidig AJ; Krengel U; Rensland H; Lautwein A; Geyer M; Scheffzek K; Goody RS; Kalbitzer HR; Pai EF
    Biochemistry; 1993 Aug; 32(33):8411-20. PubMed ID: 8357792
    [TBL] [Abstract][Full Text] [Related]  

  • 39. GTP hydrolysis mechanisms in ras p21 and in the ras-GAP complex studied by fluorescence measurements on tryptophan mutants.
    Antonny B; Chardin P; Roux M; Chabre M
    Biochemistry; 1991 Aug; 30(34):8287-95. PubMed ID: 1883817
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mechanisms of guanosine triphosphate hydrolysis by Ras and Ras-GAP proteins as rationalized by ab initio QM/MM simulations.
    Grigorenko BL; Nemukhin AV; Shadrina MS; Topol IA; Burt SK
    Proteins; 2007 Feb; 66(2):456-66. PubMed ID: 17094109
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.