127 related articles for article (PubMed ID: 8751045)
1. Kinetics and metabolism of 2-chloro-2'-deoxyadenosine and 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine in the isolated perfused rat liver.
Albertioni F; Hassan M; Silberring J; Liliemark J
Eur J Drug Metab Pharmacokinet; 1995; 20(3):225-32. PubMed ID: 8751045
[TBL] [Abstract][Full Text] [Related]
2. Stability and analysis of 2-chloro-2'-deoxyadenosine, 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine and 2-chloroadenine in human blood plasma.
Lindemalm S; Albertioni F; Liliemark J
Anticancer Drugs; 1997 Jun; 8(5):445-53. PubMed ID: 9215606
[TBL] [Abstract][Full Text] [Related]
3. Biochemical pharmacology and resistance to 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, a novel analogue of cladribine in human leukemic cells.
Lotfi K; Månsson E; Spasokoukotskaja T; Pettersson B; Liliemark J; Peterson C; Eriksson S; Albertioni F
Clin Cancer Res; 1999 Sep; 5(9):2438-44. PubMed ID: 10499616
[TBL] [Abstract][Full Text] [Related]
4. Comparison of cytotoxicity of 2-chloro- 2'-arabino-fluoro-2'-deoxyadenosine (clofarabine) with cladribine in mononuclear cells from patients with acute myeloid and chronic lymphocytic leukemia.
Lindemalm S; Liliemark J; Gruber A; Eriksson S; Karlsson MO; Wang Y; Albertioni F
Haematologica; 2003 Mar; 88(3):324-32. PubMed ID: 12651272
[TBL] [Abstract][Full Text] [Related]
5. Distribution of 2-chloro-2'-deoxyadenosine, 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, fludarabine and cytarabine in mice: a whole-body autoradiography study.
Lindemalm S; Liliemark J; Larsson BS; Albertioni F
Med Oncol; 1999 Dec; 16(4):239-44. PubMed ID: 10618686
[TBL] [Abstract][Full Text] [Related]
6. Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance.
Månsson E; Flordal E; Liliemark J; Spasokoukotskaja T; Elford H; Lagercrantz S; Eriksson S; Albertioni F
Biochem Pharmacol; 2003 Jan; 65(2):237-47. PubMed ID: 12504799
[TBL] [Abstract][Full Text] [Related]
7. Oral antilymphocyte activity and induction of apoptosis by 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine.
Carson DA; Wasson DB; Esparza LM; Carrera CJ; Kipps TJ; Cottam HB
Proc Natl Acad Sci U S A; 1992 Apr; 89(7):2970-4. PubMed ID: 1348362
[TBL] [Abstract][Full Text] [Related]
8. Metabolism and cytotoxic effects of 2-chloroadenine, the major catabolite of 2-chloro-2'-deoxyadenosine.
Bontemps F; Delacauw A; Cardoen S; Van Den Neste E; Van Den Berghe G
Biochem Pharmacol; 2000 May; 59(10):1237-43. PubMed ID: 10736424
[TBL] [Abstract][Full Text] [Related]
9. Analysis of DNA methylation of the 5' region of the deoxycytidine kinase gene in CCRF-CEM-sensitive and cladribine (CdA)- and 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine (CAFdA)-resistant cells.
Leegwater PA; De Abreu RA; Albertioni F
Cancer Lett; 1998 Aug; 130(1-2):169-73. PubMed ID: 9751270
[TBL] [Abstract][Full Text] [Related]
10. Bioavailability and bacterial degradation of rectally administered 2-chloro-2'-deoxyadenosine.
Liliemark J; Albertioni F; Edlund C; Juliusson G
J Pharm Biomed Anal; 1995 Apr; 13(4-5):661-5. PubMed ID: 9696584
[TBL] [Abstract][Full Text] [Related]
11. 2-Chloro-2'-deoxyadenosine--clinical, biochemical and pharmacokinetic considerations.
Liliemark J; Juliusson G
Arch Immunol Ther Exp (Warsz); 1994; 42(1):7-10. PubMed ID: 7503639
[TBL] [Abstract][Full Text] [Related]
12. Interspecies differences in the kinetic properties of deoxycytidine kinase elucidate the poor utility of a phase I pharmacologically directed dose-escalation concept for 2-chloro-2'-deoxyadenosine.
Reichelová V; Juliusson G; Spasokoukotskaja T; Eriksson S; Liliemark J
Cancer Chemother Pharmacol; 1995; 36(6):524-9. PubMed ID: 7554045
[TBL] [Abstract][Full Text] [Related]
13. Novel leukemic cell lines resistant to clofarabine by mechanisms of decreased active metabolite and increased antiapoptosis.
Shigemi H; Yamauchi T; Tanaka Y; Ueda T
Cancer Sci; 2013 Jun; 104(6):732-9. PubMed ID: 23421409
[TBL] [Abstract][Full Text] [Related]
14. Relationship between cladribine (CdA) plasma, intracellular CdA-5'-triphosphate (CdATP) concentration, deoxycytidine kinase (dCK), and chemotherapeutic activity in chronic lymphocytic leukemia (CLL).
Albertioni F; Lindemalm S; Eriksson S; Juliusson G; Liliemark J
Adv Exp Med Biol; 1998; 431():693-7. PubMed ID: 9598154
[TBL] [Abstract][Full Text] [Related]
15. Resistance to 2-chloro-2'-deoxyadenosine of the human B-cell leukemia cell line EHEB.
Cardoen S; Van Den Neste E; Smal C; Rosier JF; Delacauw A; Ferrant A; Van den Berghe G; Bontemps F
Clin Cancer Res; 2001 Nov; 7(11):3559-66. PubMed ID: 11705877
[TBL] [Abstract][Full Text] [Related]
16. Liquid chromatographic study of acid stability of 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, 2-chloro-2'-deoxyadenosine and related analogues.
Reichelova V; Liliemark J; Albertioni F
J Pharm Biomed Anal; 1995 Apr; 13(4-5):711-4. PubMed ID: 9696594
[No Abstract] [Full Text] [Related]
17. Comparison of the in vitro and in vivo metabolism of Cladribine (Leustatin, Movectro) in animals and human.
Scheible H; Laisney M; Wimmer E; Javornik A; Dolgos H
Xenobiotica; 2013 Dec; 43(12):1084-94. PubMed ID: 23627543
[TBL] [Abstract][Full Text] [Related]
18. Metabolism and elimination of 5,6-dimethylxanthenone-4-acetic acid in the isolated perfused rat liver.
Webster LK; Ellis AG; Kestell P; Rewcastle GW
Drug Metab Dispos; 1995 Mar; 23(3):363-8. PubMed ID: 7628302
[TBL] [Abstract][Full Text] [Related]
19. Molecular and biochemical mechanisms of fludarabine and cladribine resistance in a human promyelocytic cell line.
Månsson E; Spasokoukotskaja T; Sällström J; Eriksson S; Albertioni F
Cancer Res; 1999 Dec; 59(23):5956-63. PubMed ID: 10606241
[TBL] [Abstract][Full Text] [Related]
20. 2-Chloro-2'-deoxyadenosine inhibits DNA repair synthesis and potentiates UVC cytotoxicity in chronic lymphocytic leukemia B lymphocytes.
Van Den Neste E; Cardoen S; Husson B; Rosier JF; Delacauw A; Ferrant A; Van den Berghe G; Bontemps F
Leukemia; 2002 Jan; 16(1):36-43. PubMed ID: 11840261
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]