BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 8760273)

  • 1. Characterization, application and potential uses of biotin-tagged inhibitors for lymphocyte serine proteases (granzymes).
    Winkler U; Allison NJ; Woodard SL; Gault RA; Ewoldt GR; Kam CM; Abuelyaman A; Powers JC; Hudig D
    Mol Immunol; 1996; 33(7-8):615-23. PubMed ID: 8760273
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and kinetic studies of diphenyl 1-(N-peptidylamino)alkanephosphonate esters and their biotinylated derivatives as inhibitors of serine proteases and probes for lymphocyte granzymes.
    Abuelyaman AS; Jackson DS; Hudig D; Woodard SL; Powers JC
    Arch Biochem Biophys; 1997 Aug; 344(2):271-80. PubMed ID: 9264539
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors.
    Kam CM; Hudig D; Powers JC
    Biochim Biophys Acta; 2000 Mar; 1477(1-2):307-23. PubMed ID: 10708866
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sulfonyl fluoride serine protease inhibitors inactivate RNK-16 lymphocyte granule proteases and reduce lysis by granule extracts and perforin.
    Ewoldt GR; Winkler U; Powers JC; Hudig D
    Mol Immunol; 1992 Jun; 29(6):713-21. PubMed ID: 1603092
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The function of lymphocyte proteases. Inhibition and restoration of granule-mediated lysis with isocoumarin serine protease inhibitors.
    Hudig D; Allison NJ; Pickett TM; Winkler U; Kam CM; Powers JC
    J Immunol; 1991 Aug; 147(4):1360-8. PubMed ID: 1869829
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins.
    Odake S; Kam CM; Narasimhan L; Poe M; Blake JT; Krahenbuhl O; Tschopp J; Powers JC
    Biochemistry; 1991 Feb; 30(8):2217-27. PubMed ID: 1998680
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chymase-directed serine protease inhibitor that reacts with a single 30-kDa granzyme and blocks NK-mediated cytotoxicity.
    Woodard SL; Jackson DS; Abuelyaman AS; Powers JC; Winkler U; Hudig D
    J Immunol; 1994 Dec; 153(11):5016-25. PubMed ID: 7963562
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Purification and characterization of lymphocyte chymase I, a granzyme implicated in perforin-mediated lysis.
    Woodard SL; Fraser SA; Winkler U; Jackson DS; Kam CM; Powers JC; Hudig D
    J Immunol; 1998 May; 160(10):4988-93. PubMed ID: 9590247
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selective isocoumarin serine protease inhibitors block RNK-16 lymphocyte granule-mediated cytolysis.
    Hudig D; Allison NJ; Kam CM; Powers JC
    Mol Immunol; 1989 Aug; 26(8):793-8. PubMed ID: 2811873
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synergistic inhibition of human cell-mediated cytotoxicity by complement component antisera indicates that target cell lysis may result from an enzymatic cascade involving granzymes and perforin.
    Brahmi Z; Csipo I; Bochan MR; Su B; Montel AH; Morse PA
    Nat Immun; 1995 Sep; 14(5-6):271-85. PubMed ID: 8933821
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Granzymes: a family of lymphocyte granule serine proteases.
    Trapani JA
    Genome Biol; 2001; 2(12):REVIEWS3014. PubMed ID: 11790262
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes.
    Edwards KM; Kam CM; Powers JC; Trapani JA
    J Biol Chem; 1999 Oct; 274(43):30468-73. PubMed ID: 10521426
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Granzymes: a variety of serine protease specificities encoded by genetically distinct subfamilies.
    Smyth MJ; O'Connor MD; Trapani JA
    J Leukoc Biol; 1996 Nov; 60(5):555-62. PubMed ID: 8929545
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Killing by cytotoxic T cells and natural killer cells: multiple granule serine proteases as initiators of DNA fragmentation.
    Trapani JA; Smyth MJ
    Immunol Cell Biol; 1993 Jun; 71 ( Pt 3)():201-8. PubMed ID: 8349302
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Generation of antigenic peptides by lymphocyte granule serine proteases (granzymes).
    Carter CR; Sayers TJ; Wiltrout RH; Turcovski-Corrales SM; Taub DD
    Cell Immunol; 1996 Sep; 172(2):235-45. PubMed ID: 8964086
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation.
    Jenne DE; Tschopp J
    Immunol Rev; 1988 Mar; 103():53-71. PubMed ID: 3292396
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hypothesis: cytotoxic lymphocyte granule serine proteases activate target cell endonucleases to trigger apoptosis.
    Smyth MJ; Browne KA; Thia KY; Apostolidis VA; Kershaw MH; Trapani JA
    Clin Exp Pharmacol Physiol; 1994 Jan; 21(1):67-70. PubMed ID: 8156655
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nonspecific cytotoxic cells of teleosts are armed with multiple granzymes and other components of the granule exocytosis pathway.
    Praveen K; Leary JH; Evans DL; Jaso-Friedmann L
    Mol Immunol; 2006 Mar; 43(8):1152-62. PubMed ID: 16137766
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo.
    Pham CT; Ley TJ
    Proc Natl Acad Sci U S A; 1999 Jul; 96(15):8627-32. PubMed ID: 10411926
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biotinylated isocoumarins, new inhibitors and reagents for detection, localization, and isolation of serine proteases.
    Kam CM; Abuelyaman AS; Li Z; Hudig D; Powers JC
    Bioconjug Chem; 1993; 4(6):560-7. PubMed ID: 8305526
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.