114 related articles for article (PubMed ID: 8761436)
1. Production of 8-hydroxy-2'-deoxguanosine in DNA by microsomal activation of tamoxifen and 4-hydroxytamoxifen.
Ye Q; Bodell WJ
Carcinogenesis; 1996 Aug; 17(8):1747-50. PubMed ID: 8761436
[TBL] [Abstract][Full Text] [Related]
2. Microsomal and peroxidase activation of 4-hydroxy-tamoxifen to form DNA adducts: comparison with DNA adducts formed in Sprague-Dawley rats treated with tamoxifen.
Pathak DN; Pongracz K; Bodell WJ
Carcinogenesis; 1995 Jan; 16(1):11-5. PubMed ID: 7834794
[TBL] [Abstract][Full Text] [Related]
3. Influence of polyethylene glycol and acetone on the in vitro biotransformation of tamoxifen and alprazolam by human liver microsomes.
Cotreau-Bibbo MM; von Moltke LL; Greenblatt DJ
J Pharm Sci; 1996 Nov; 85(11):1180-5. PubMed ID: 8923322
[TBL] [Abstract][Full Text] [Related]
4. Evidence that the catechol 3,4-Dihydroxytamoxifen is a proximate intermediate to the reactive species binding covalently to proteins.
Dehal SS; Kupfer D
Cancer Res; 1996 Mar; 56(6):1283-90. PubMed ID: 8640815
[TBL] [Abstract][Full Text] [Related]
5. DNA adduct formation by tamoxifen with rat and human liver microsomal activation systems.
Pathak DN; Bodell WJ
Carcinogenesis; 1994 Mar; 15(3):529-32. PubMed ID: 8118938
[TBL] [Abstract][Full Text] [Related]
6. Cytochrome P-450 3A and 2D6 catalyze ortho hydroxylation of 4-hydroxytamoxifen and 3-hydroxytamoxifen (droloxifene) yielding tamoxifen catechol: involvement of catechols in covalent binding to hepatic proteins.
Dehal SS; Kupfer D
Drug Metab Dispos; 1999 Jun; 27(6):681-8. PubMed ID: 10348797
[TBL] [Abstract][Full Text] [Related]
7. Tamoxifen reduces endogenous and UV light-induced oxidative damage to DNA, lipid and protein in vitro and in vivo.
Wei H; Cai Q; Tian L; Lebwohl M
Carcinogenesis; 1998 Jun; 19(6):1013-8. PubMed ID: 9667739
[TBL] [Abstract][Full Text] [Related]
8. Phenytoin-initiated DNA oxidation in murine embryo culture, and embryo protection by the antioxidative enzymes superoxide dismutase and catalase: evidence for reactive oxygen species-mediated DNA oxidation in the molecular mechanism of phenytoin teratogenicity.
Winn LM; Wells PG
Mol Pharmacol; 1995 Jul; 48(1):112-20. PubMed ID: 7623765
[TBL] [Abstract][Full Text] [Related]
9. HPLC investigation on Ni(II)-mediated DNA damage in the presence of t-butyl hydroperoxide and glutathione.
Shi X; Mao Y; Ahmed N; Jiang H
J Inorg Biochem; 1995 Feb; 57(2):91-102. PubMed ID: 7861128
[TBL] [Abstract][Full Text] [Related]
10. Iron-stimulated ring-opening of benzene in a mouse liver microsomal system. Mechanistic studies and formation of a new metabolite.
Zhang Z; Goldstein BD; Witz G
Biochem Pharmacol; 1995 Nov; 50(10):1607-17. PubMed ID: 7503763
[TBL] [Abstract][Full Text] [Related]
11. Detection of N-(deoxyguanosin-8-yl)-2-fluorenamine in DNA of peritoneal serosa and liver after intraperitoneal exposure of rats to N-hydroxy-N-2-fluorenylbenzamide or N-hydroxy-N-2-fluorenylacetamide.
Malejka-Giganti D; Ritter CL; Fullerton NF; Beland FA
Carcinogenesis; 1994 Dec; 15(12):2883-90. PubMed ID: 8001251
[TBL] [Abstract][Full Text] [Related]
12. Spontaneous and 2-nitropropane induced levels of 8-hydroxy-2'-deoxyguanosine in liver DNA of rats fed iron-deficient or manganese- and copper-deficient diets.
Adachi S; Takemoto K; Hirosue T; Hosogai Y
Carcinogenesis; 1993 Feb; 14(2):265-8. PubMed ID: 8382115
[TBL] [Abstract][Full Text] [Related]
13. Glucuronidation of active tamoxifen metabolites by the human UDP glucuronosyltransferases.
Sun D; Sharma AK; Dellinger RW; Blevins-Primeau AS; Balliet RM; Chen G; Boyiri T; Amin S; Lazarus P
Drug Metab Dispos; 2007 Nov; 35(11):2006-14. PubMed ID: 17664247
[TBL] [Abstract][Full Text] [Related]
14. DNA cleavage and 8-hydroxydeoxyguanosine formation caused by tamoxifen derivatives in vitro.
Okubo T; Nagai F; Ushiyama K; Yokoyama Y; Ozawa S; Kano K; Tomita S; Kubo H; Kano I
Cancer Lett; 1998 Jan; 122(1-2):9-15. PubMed ID: 9464485
[TBL] [Abstract][Full Text] [Related]
15. Acidic metabolites of tamoxifen. Aspects of formation and fate in the female rat.
Ruenitz PC; Bai X
Drug Metab Dispos; 1995 Sep; 23(9):993-8. PubMed ID: 8565791
[TBL] [Abstract][Full Text] [Related]
16. Toluene inhalation induced 8-hydroxy-2'-deoxyguanosine formation as the peroxidative degeneration in rat organs.
Tokunaga I; Gotohda T; Ishigami A; Kitamura O; Kubo S
Leg Med (Tokyo); 2003 Mar; 5(1):34-41. PubMed ID: 12935648
[TBL] [Abstract][Full Text] [Related]
17. Activation of 4-hydroxytamoxifen and the tamoxifen derivative metabolite E by uterine peroxidase to form DNA adducts: comparison with DNA adducts formed in the uterus of Sprague-Dawley rats treated with tamoxifen.
Pathak DN; Pongracz K; Bodell WJ
Carcinogenesis; 1996 Sep; 17(9):1785-90. PubMed ID: 8824496
[TBL] [Abstract][Full Text] [Related]
18. Tamoxifen: evidence by 32P-postlabeling and use of metabolic inhibitors for two distinct pathways leading to mouse hepatic DNA adduct formation and identification of 4-hydroxytamoxifen as a proximate metabolite.
Randerath K; Moorthy B; Mabon N; Sriram P
Carcinogenesis; 1994 Oct; 15(10):2087-94. PubMed ID: 7955037
[TBL] [Abstract][Full Text] [Related]
19. Characterization of tamoxifen and 4-hydroxytamoxifen glucuronidation by human UGT1A4 variants.
Sun D; Chen G; Dellinger RW; Duncan K; Fang JL; Lazarus P
Breast Cancer Res; 2006; 8(4):R50. PubMed ID: 16884532
[TBL] [Abstract][Full Text] [Related]
20. Tamoxifen metabolism in rat liver microsomes: identification of a dimeric metabolite derived from free radical intermediates by liquid chromatography/mass spectrometry.
Jones RM; Yuan ZX; Lim CK
Rapid Commun Mass Spectrom; 1999; 13(4):211-5. PubMed ID: 10097399
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
