BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

282 related articles for article (PubMed ID: 8763840)

  • 1. Cytotoxic mechanisms of anti-tumour quinones in parental and resistant lymphoblasts.
    Halinska A; Belej T; O'Brien PJ
    Br J Cancer Suppl; 1996 Jul; 27():S23-7. PubMed ID: 8763840
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activity of quinone alkylating agents in quinone-resistant cells.
    Begleiter A; Leith MK
    Cancer Res; 1990 May; 50(10):2872-6. PubMed ID: 1692249
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J; Oleschuk CJ; Guziec F; Guziec L; Fiterman DJ; Monterrosa C; Begleiter A
    Cancer Chemother Pharmacol; 2002 Feb; 49(2):101-10. PubMed ID: 11862423
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of L5178Y murine lymphoblasts resistant to quinone antitumor agents.
    Begleiter A; Leith MK; McClarty G; Beenken S; Goldenberg GJ; Wright JA
    Cancer Res; 1988 Apr; 48(7):1727-35. PubMed ID: 3127038
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under hypoxia.
    Begleiter A; Robotham E; Leith MK
    Mol Pharmacol; 1992 Apr; 41(4):677-82. PubMed ID: 1373799
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular mechanisms of trenimon-induced cytotoxicity in resistant L5178Y/HBM10 cells.
    Silva JM; O'Brien PJ
    Int J Radiat Oncol Biol Phys; 1992; 22(4):639-42. PubMed ID: 1371987
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modulation of trenimon-induced cytotoxicity by DT-diaphorase in isolated rat hepatocytes under aerobic versus hypoxic conditions.
    Silva JM; Rao DN; O'Brien PJ
    Cancer Res; 1992 Jun; 52(11):3015-21. PubMed ID: 1375532
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolism of diaziquone by NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells.
    Siegel D; Gibson NW; Preusch PC; Ross D
    Cancer Res; 1990 Nov; 50(22):7293-300. PubMed ID: 2121335
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells.
    Siegel D; Gibson NW; Preusch PC; Ross D
    Cancer Res; 1990 Dec; 50(23):7483-9. PubMed ID: 1701346
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Increased sensitivity of quinone resistant cells to mitomycin C.
    Begleiter A; Robotham E; Lacey G; Leith MK
    Cancer Lett; 1989 Jun; 45(3):173-6. PubMed ID: 2471583
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced cytotoxicity of mitomycin C in human tumour cells with inducers of DT-diaphorase.
    Wang X; Doherty GP; Leith MK; Curphey TJ; Begleiter A
    Br J Cancer; 1999 Jun; 80(8):1223-30. PubMed ID: 10376975
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Mitomycin C and its bioreduction: relevance of NAD(P)H: quinone oxidoreductase activity to mitomycin C-induced DNA damage and cytotoxicity].
    Nishiyama M; Saeki S; Aogi K; Hirabayashi N; Toge T
    Gan To Kagaku Ryoho; 1993 Jun; 20(8):1037-41. PubMed ID: 7685584
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Advances in research on DT-diaphorase--catalytic properties, regulation of activity and significance in the detoxication of foreign compounds.
    Horie S
    Kitasato Arch Exp Med; 1990 Apr; 63(1):11-30. PubMed ID: 2125671
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Studies of pyrrolo[1,2-alpha]benzimidazolequinone DT-diaphorase substrate activity, topoisomerase II inhibition activity, and DNA reductive alkylation.
    Skibo EB; Gordon S; Bess L; Boruah R; Heileman MJ
    J Med Chem; 1997 Apr; 40(9):1327-39. PubMed ID: 9135030
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nicotinamide adenine dinucleotide (phosphate): quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumor quinones: quinone cytotoxicity and selectivity in human lung and breast cancer cell lines.
    Beall HD; Murphy AM; Siegel D; Hargreaves RH; Butler J; Ross D
    Mol Pharmacol; 1995 Sep; 48(3):499-504. PubMed ID: 7565631
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-activity study with bioreductive benzoquinone alkylating agents: effects on DT-diaphorase-mediated DNA crosslink and strand break formation in relation to mechanisms of cytotoxicity.
    Fourie J; Guziec F; Guziec L; Monterrosa C; Fiterman DJ; Begleiter A
    Cancer Chemother Pharmacol; 2004 Mar; 53(3):191-203. PubMed ID: 14614574
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Relationship between DT-diaphorase-mediated metabolism of a series of aziridinylbenzoquinones and DNA damage and cytotoxicity.
    Gibson NW; Hartley JA; Butler J; Siegel D; Ross D
    Mol Pharmacol; 1992 Sep; 42(3):531-6. PubMed ID: 1406604
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Induction of DT-diaphorase in cancer chemoprevention and chemotherapy.
    Begleiter A; Leith MK; Curphey TJ; Doherty GP
    Oncol Res; 1997; 9(6-7):371-82. PubMed ID: 9406243
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enzyme-directed bioreductive drug development revisited: a commentary on recent progress and future prospects with emphasis on quinone anticancer agents and quinone metabolizing enzymes, particularly DT-diaphorase.
    Workman P
    Oncol Res; 1994; 6(10-11):461-75. PubMed ID: 7620214
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Gene targeting of DT-diaphorase in mouse embryonic stem cells: establishment of null mutant and its mitomycin C-resistance.
    Yoshida T; Tsuda H
    Biochem Biophys Res Commun; 1995 Sep; 214(2):701-8. PubMed ID: 7677784
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.