These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

276 related articles for article (PubMed ID: 8765468)

  • 1. Comparison of methotrexate polyglutamylation in L1210 leukemia cells when influx is mediated by the reduced folate carrier or the folate receptor. Lack of evidence for influx route-specific effects.
    Spinella MJ; Brigle KE; Freemantle SJ; Sierra EE; Goldman ID
    Biochem Pharmacol; 1996 Sep; 52(5):703-12. PubMed ID: 8765468
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distinguishing between folate receptor-alpha-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells.
    Spinella MJ; Brigle KE; Sierra EE; Goldman ID
    J Biol Chem; 1995 Apr; 270(14):7842-9. PubMed ID: 7713875
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparison of transport properties of the reduced folate carrier and folate receptor in murine L1210 leukemia cells.
    Sierra EE; Brigle KE; Spinella MJ; Goldman ID
    Biochem Pharmacol; 1995 Oct; 50(8):1287-94. PubMed ID: 7488246
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of folate transport mediated by a low pH route in mouse L1210 leukemia cells with defective reduced folate carrier function.
    Sierra EE; Goldman ID
    Biochem Pharmacol; 1998 May; 55(9):1505-12. PubMed ID: 10076544
    [TBL] [Abstract][Full Text] [Related]  

  • 5. pH dependence of methotrexate transport by the reduced folate carrier and the folate receptor in L1210 leukemia cells. Further evidence for a third route mediated at low pH.
    Sierra EE; Brigle KE; Spinella MJ; Goldman ID
    Biochem Pharmacol; 1997 Jan; 53(2):223-31. PubMed ID: 9037255
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increased expression and genomic organization of a folate-binding protein homologous to the human placental isoform in L1210 murine leukemia cell lines with a defective reduced folate carrier.
    Brigle KE; Seither RL; Westin EH; Goldman ID
    J Biol Chem; 1994 Feb; 269(6):4267-72. PubMed ID: 8307991
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line.
    Brigle KE; Spinella MJ; Sierra EE; Goldman ID
    J Biol Chem; 1995 Sep; 270(39):22974-9. PubMed ID: 7559435
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A mutated murine reduced folate carrier (RFC1) with increased affinity for folic acid, decreased affinity for methotrexate, and an obligatory anion requirement for transport function.
    Zhao R; Assaraf YG; Goldman ID
    J Biol Chem; 1998 Jul; 273(30):19065-71. PubMed ID: 9668089
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells.
    Matherly LH; Barlowe CK; Goldman ID
    Cancer Res; 1986 Feb; 46(2):588-93. PubMed ID: 2416428
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discrimination among reduced folates and methotrexate as transport substrates by a phenylalanine substitution for serine within the predicted eighth transmembrane domain of the reduced folate carrier.
    Zhao R; Gao F; Goldman ID
    Biochem Pharmacol; 1999 Nov; 58(10):1615-24. PubMed ID: 10535753
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rescue effect of exogenous reduced folates on methotrexate polyglutamylation and dihydrofolate reductase activity in L1210 cells.
    Balińska M
    Acta Biochim Pol; 1988; 35(3):199-205. PubMed ID: 2469275
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impact of overexpression of the reduced folate carrier (RFC1), an anion exchanger, on concentrative transport in murine L1210 leukemia cells.
    Zhao R; Seither R; Brigle KE; Sharina IG; Wang PJ; Goldman ID
    J Biol Chem; 1997 Aug; 272(34):21207-12. PubMed ID: 9261128
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of methotrexate polyglutamates in L1210 murine leukemia cells.
    Whitehead VM
    Cancer Res; 1977 Feb; 37(2):408-12. PubMed ID: 832265
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Membrane protein changes in an L1210 leukemia cell line with a translocation defect in the methotrexate-tetrahydrofolate cofactor transport carrier.
    Schuetz JD; Westin EH; Matherly LH; Pincus R; Swerdlow PS; Goldman ID
    J Biol Chem; 1989 Sep; 264(27):16261-7. PubMed ID: 2777791
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Carrier-mediated transport of folate compounds in L1210 cells. Initial rate kinetics and extent of duality of entry routes for folic acid and diastereomers of 5-methyltetrahydrohomofolate in the presence of physiological anions.
    Sirotnak FM; Goutas LJ; Jacobsen DM; Mines LS; Barrueco JR; Gaumont Y; Kisliuk RL
    Biochem Pharmacol; 1987 May; 36(10):1659-67. PubMed ID: 3593392
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Membrane transport of natural folates and antifolate compounds in murine L1210 leukemia cells: role of carrier- and receptor-mediated transport systems.
    Westerhof GR; Jansen G; van Emmerik N; Kathmann I; Rijksen G; Jackman AL; Schornagel JH
    Cancer Res; 1991 Oct; 51(20):5507-13. PubMed ID: 1655252
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evidence for a functional defect in the translocation of the methotrexate transport carrier in a methotrexate-resistant murine L1210 leukemia cell line.
    Schuetz JD; Matherly LH; Westin EH; Goldman ID
    J Biol Chem; 1988 Jul; 263(20):9840-7. PubMed ID: 2838483
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
    Mauritz R; Peters GJ; Priest DG; Assaraf YG; Drori S; Kathmann I; Noordhuis P; Bunni MA; Rosowsky A; Schornagel JH; Pinedo HM; Jansen G
    Biochem Pharmacol; 2002 Jan; 63(2):105-15. PubMed ID: 11841783
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The mechanism of transport of the multitargeted antifolate (MTA) and its cross-resistance pattern in cells with markedly impaired transport of methotrexate.
    Zhao R; Babani S; Gao F; Liu L; Goldman ID
    Clin Cancer Res; 2000 Sep; 6(9):3687-95. PubMed ID: 10999762
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dynamics of antifolate transport via the reduced folate carrier and the membrane folate receptor in murine leukaemia cells in vitro and in vivo.
    Mauritz R; Peters GJ; Kathmann I; Teshale H; Noordhuis P; Comijn EM; Pinedo HM; Jansen G
    Cancer Chemother Pharmacol; 2008 Nov; 62(6):937-48. PubMed ID: 18283461
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.