199 related articles for article (PubMed ID: 8767348)
1. Ca2+ sensitization in idiopathic dilated human myocardium. Differential in vitro effects of (+)-(5-methyl-6-phenyl)-1,3,5,6-tetrahydro-3,6-methano-1,5-benzodiazoci ne-2,4-dione, a novel purely Ca2+sensitizing agent, and (+)-5-(1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydroquinolin-6-yl)-6-meth yl-3, 6-dihydro-2H-1,3,4-thiadiazin-2-one on skinned fibres and isolated ventricular strips.
Herzig JW; Chiesi M; Depersin H; Grüninger S; Hasenfuss G; Kubalek R; Leutert T; Pieske B; Pioch K; Wenk P; Holubarsch C
Arzneimittelforschung; 1996 Jun; 46(6):586-93. PubMed ID: 8767348
[TBL] [Abstract][Full Text] [Related]
2. 5-Methyl-6-phenyl-1,3,5,6-tetrahydro-3,6-methano-1,5-benzodiazocine-2,4-dione (BA 41899): representative of a novel class of purely calcium-sensitizing agents.
Herold P; Herzig JW; Wenk P; Leutert T; Zbinden P; Fuhrer W; Stutz S; Schenker K; Meier M; Rihs G
J Med Chem; 1995 Jul; 38(15):2946-54. PubMed ID: 7636855
[TBL] [Abstract][Full Text] [Related]
3. CGP-48506 increases contractility of ventricular myocytes and myofilaments by effects on actin-myosin reaction.
Wolska BM; Kitada Y; Palmiter KA; Westfall MV; Johnson MD; Solaro RJ
Am J Physiol; 1996 Jan; 270(1 Pt 2):H24-32. PubMed ID: 8769730
[TBL] [Abstract][Full Text] [Related]
4. The two mechanisms of action of racemic cardiotonic EMD 53998, calcium sensitization and phosphodiesterase inhibition, reside in different enantiomers.
Lues I; Beier N; Jonas R; Klockow M; Haeusler G
J Cardiovasc Pharmacol; 1993 Jun; 21(6):883-92. PubMed ID: 7687712
[TBL] [Abstract][Full Text] [Related]
5. A novel positive inotropic substance enhances contractility without increasing the Ca2+ transient in rat myocardium.
Ferroni C; Hano O; Ventura C; Lakatta EG; Klockow M; Spurgeon H; Capogrossi MC
J Mol Cell Cardiol; 1991 Mar; 23(3):325-31. PubMed ID: 1880816
[TBL] [Abstract][Full Text] [Related]
6. Effects of the Ca2+ sensitizers EMD 57033 and CGP 48506 on myocardial contractility and Ca2+ transients in human ventricular and atrial myocardium.
Brixius K; Reicke S; Reuter H; Schwinger RH
Z Kardiol; 2002 Apr; 91(4):312-8. PubMed ID: 12063703
[TBL] [Abstract][Full Text] [Related]
7. EMD 53998 acts as Ca(2+)-sensitizer and phosphodiesterase III-inhibitor in human myocardium.
Uhlmann R; Schwinger RH; Lues I; Erdmann E
Basic Res Cardiol; 1995; 90(5):365-71. PubMed ID: 8585857
[TBL] [Abstract][Full Text] [Related]
8. The novel inotropic agent CGP 48506 alters force primarily by Ca(2+)-independent mechanisms in porcine skinned trabeculae.
Palmer S; Di Bello S; Davenport SL; Herzig JW
Cardiovasc Res; 1996 Aug; 32(2):411-21. PubMed ID: 8796129
[TBL] [Abstract][Full Text] [Related]
9. (-)-Enantiomer EMD 57439 antagonizes the Ca2+ sensitizing effect of (+)-enantiomer EMD 57033 on diastolic function but not on systolic function in rabbit ventricular cardiomyocytes.
Sugawara H; Endoh M
Jpn J Pharmacol; 1999 May; 80(1):55-65. PubMed ID: 10446757
[TBL] [Abstract][Full Text] [Related]
10. Different effect of the Ca(2+) sensitizers EMD 57033 and CGP 48506 on cross-bridge cycling in human myocardium.
Brixius K; Mehlhorn U; Bloch W; Schwinger RH
J Pharmacol Exp Ther; 2000 Dec; 295(3):1284-90. PubMed ID: 11082466
[TBL] [Abstract][Full Text] [Related]
11. Novel diazinone derivatives separate myofilament Ca2+ sensitization and phosphodiesterase III inhibitory effects in guinea pig myocardium.
Ventura C; Miller R; Wolf HP; Beier N; Jonas R; Klockow M; Lues I; Hano O; Spurgeon HA; Lakatta EG
Circ Res; 1992 Jun; 70(6):1081-90. PubMed ID: 1533576
[TBL] [Abstract][Full Text] [Related]
12. The novel cardiotonic agent EMD 53 998 is a potent "calcium sensitizer".
Beier N; Harting J; Jonas R; Klockow M; Lues I; Haeusler G
J Cardiovasc Pharmacol; 1991 Jul; 18(1):17-27. PubMed ID: 1719287
[TBL] [Abstract][Full Text] [Related]
13. In vivo evidence of positive inotropism of EMD 57033 through calcium sensitization.
Haeusler G; Jonas R; Minck KO; Schliep HJ; Schelling P; Weygandt H; Lues I
J Cardiovasc Pharmacol; 1997 May; 29(5):647-55. PubMed ID: 9213208
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart.
Orstavik O; Ata SH; Riise J; Dahl CP; Andersen GØ; Levy FO; Skomedal T; Osnes JB; Qvigstad E
Br J Pharmacol; 2014 Dec; 171(23):5169-81. PubMed ID: 24547784
[TBL] [Abstract][Full Text] [Related]
15. Calcium sensitization as new principle of inotropic therapy in end-stage heart failure?
Zimmermann N; Boknik P; Gams E; Herzig JW; Neumann J; Scholz H
Eur J Cardiothorac Surg; 1998 Jul; 14(1):70-5. PubMed ID: 9726618
[TBL] [Abstract][Full Text] [Related]
16. The effects of EMD 57033 on rigor tension in porcine skinned cardiac trabecula.
Palmer S; Di Bello S; Herzig JW
Eur J Pharmacol; 1995 Dec; 294(1):83-90. PubMed ID: 8788419
[TBL] [Abstract][Full Text] [Related]
17. Stereoselective actions of thiadiazinones on canine cardiac myocytes and myofilaments.
Solaro RJ; Gambassi G; Warshaw DM; Keller MR; Spurgeon HA; Beier N; Lakatta EG
Circ Res; 1993 Dec; 73(6):981-90. PubMed ID: 8222092
[TBL] [Abstract][Full Text] [Related]
18. Enantiomeric dissection of the effects of the inotropic agent, EMD 53998, in single cardiac myocytes.
Gambassi G; Capogrossi MC; Klockow M; Lakatta EG
Am J Physiol; 1993 Mar; 264(3 Pt 2):H728-38. PubMed ID: 8384421
[TBL] [Abstract][Full Text] [Related]
19. Positive inotropic effects of calcium sensitizers on normal and failing cardiac myocytes.
Tsutsui H; Kinugawa S; Ide T; Hayashidani S; Suematsu N; Satoh S; Nakamura R; Egashira K; Takeshita A
J Cardiovasc Pharmacol; 2001 Jan; 37(1):16-24. PubMed ID: 11152370
[TBL] [Abstract][Full Text] [Related]
20. The Ca2+ sensitizer EMD 53998 antagonizes the effect of 2,3-butanedione monoxime on skinned cardiac muscle fibres.
Barth Z; Strauss JD; Dohet C; Ruegg JC
Eur J Pharmacol; 1996 Feb; 296(3):285-9. PubMed ID: 8904080
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
