BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 8768755)

  • 1. Pharmacokinetics and tissue disposition of a chimeric oligodeoxynucleoside phosphorothioate in rats after intravenous administration.
    Zhang R; Iyer RP; Yu D; Tan W; Zhang X; Lu Z; Zhao H; Agrawal S
    J Pharmacol Exp Ther; 1996 Aug; 278(2):971-9. PubMed ID: 8768755
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacokinetic properties of several novel oligonucleotide analogs in mice.
    Crooke ST; Graham MJ; Zuckerman JE; Brooks D; Conklin BS; Cummins LL; Greig MJ; Guinosso CJ; Kornbrust D; Manoharan M; Sasmor HM; Schleich T; Tivel KL; Griffey RH
    J Pharmacol Exp Ther; 1996 May; 277(2):923-37. PubMed ID: 8627575
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vivo stability, disposition and metabolism of a "hybrid" oligonucleotide phosphorothioate in rats.
    Zhang R; Lu Z; Zhao H; Zhang X; Diasio RB; Habus I; Jiang Z; Iyer RP; Yu D; Agrawal S
    Biochem Pharmacol; 1995 Aug; 50(4):545-56. PubMed ID: 7646561
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacokinetics of G3139, a phosphorothioate oligodeoxynucleotide antisense to bcl-2, after intravenous administration or continuous subcutaneous infusion to mice.
    Raynaud FI; Orr RM; Goddard PM; Lacey HA; Lancashire H; Judson IR; Beck T; Bryan B; Cotter FE
    J Pharmacol Exp Ther; 1997 Apr; 281(1):420-7. PubMed ID: 9103525
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacokinetics and metabolism in mice of a phosphorothioate oligonucleotide antisense inhibitor of C-raf-1 kinase expression.
    Geary RS; Leeds JM; Fitchett J; Burckin T; Truong L; Spainhour C; Creek M; Levin AA
    Drug Metab Dispos; 1997 Nov; 25(11):1272-81. PubMed ID: 9351904
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Disposition of the 14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats.
    Cossum PA; Sasmor H; Dellinger D; Truong L; Cummins L; Owens SR; Markham PM; Shea JP; Crooke S
    J Pharmacol Exp Ther; 1993 Dec; 267(3):1181-90. PubMed ID: 8166890
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vivo stability and disposition of a self-stabilized oligodeoxynucleotide phosphorothioate in rats.
    Zhang R; Lu Z; Zhang X; Zhao H; Diasio RB; Liu T; Jiang Z; Agrawal S
    Clin Chem; 1995 Jun; 41(6 Pt 1):836-43. PubMed ID: 7768001
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacokinetics, tissue distribution, and stability of antisense oligodeoxynucleotide phosphorothioate ISIS 3466 in mice.
    Saijo Y; Perlaky L; Wang H; Busch H
    Oncol Res; 1994; 6(6):243-9. PubMed ID: 7865900
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacokinetics of an anti-human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects.
    Zhang R; Yan J; Shahinian HK; Amin G; Lu Z; Liu T; Saag MS; Jiang Z; Temsamani J; Martin RR
    Clin Pharmacol Ther; 1995 Jul; 58(1):44-53. PubMed ID: 7628182
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacokinetics and tissue distribution in rats of an oligodeoxynucleotide phosphorothioate (GEM 91) developed as a therapeutic agent for human immunodeficiency virus type-1.
    Zhang R; Diasio RB; Lu Z; Liu T; Jiang Z; Galbraith WM; Agrawal S
    Biochem Pharmacol; 1995 Mar; 49(7):929-39. PubMed ID: 7741765
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacokinetic properties of 2'-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats.
    Geary RS; Watanabe TA; Truong L; Freier S; Lesnik EA; Sioufi NB; Sasmor H; Manoharan M; Levin AA
    J Pharmacol Exp Ther; 2001 Mar; 296(3):890-7. PubMed ID: 11181921
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacokinetics of a 14C-labeled phosphorothioate oligonucleotide, ISIS 2105, after intradermal administration to rats.
    Cossum PA; Truong L; Owens SR; Markham PM; Shea JP; Crooke ST
    J Pharmacol Exp Ther; 1994 Apr; 269(1):89-94. PubMed ID: 8169856
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biodistribution and metabolism of internally 3H-labeled oligonucleotides. II. 3',5'-blocked oligonucleotides.
    Sands H; Gorey-Feret LJ; Ho SP; Bao Y; Cocuzza AJ; Chidester D; Hobbs FW
    Mol Pharmacol; 1995 Mar; 47(3):636-46. PubMed ID: 7700261
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Preclinical pharmacology of the natural product anticancer agent bryostatin 1, an activator of protein kinase C.
    Zhang X; Zhang R; Zhao H; Cai H; Gush KA; Kerr RG; Pettit GR; Kraft AS
    Cancer Res; 1996 Feb; 56(4):802-8. PubMed ID: 8631017
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Maternal and fetal distribution of a phosphorothioate oligonucleotide in rats after intravenous infusion.
    Soucy NV; Riley JP; Templin MV; Geary R; de Peyster A; Levin AA
    Birth Defects Res B Dev Reprod Toxicol; 2006 Feb; 77(1):22-8. PubMed ID: 16496297
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Orally active inhibitors of human leukocyte elastase. I. Disposition of L-683,845 in rats and rhesus monkeys.
    Vincent SH; Painter SK; Krieter PA; Colletti AE; Lyszack E; Rosegay A; Dean D; Luffer-Atlas D; Miller RR; Cioffe C; Chiu SH
    Drug Metab Dispos; 1996 Dec; 24(12):1369-77. PubMed ID: 8971144
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of aspirin on protein binding and tissue disposition of oligonucleotide phosphorothioate in rats.
    Agrawal S; Zhang X; Cai Q; Kandimalla ER; Manning A; Jiang Z; Marcel T; Zhang R
    J Drug Target; 1998; 5(4):303-12. PubMed ID: 9713979
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Absorption, tissue distribution and in vivo stability in rats of a hybrid antisense oligonucleotide following oral administration.
    Agrawal S; Zhang X; Lu Z; Zhao H; Tamburin JM; Yan J; Cai H; Diasio RB; Habus I; Jiang Z
    Biochem Pharmacol; 1995 Aug; 50(4):571-6. PubMed ID: 7646565
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biodistribution and metabolism of internally 3H-labeled oligonucleotides. I. Comparison of a phosphodiester and a phosphorothioate.
    Sands H; Gorey-Feret LJ; Cocuzza AJ; Hobbs FW; Chidester D; Trainor GL
    Mol Pharmacol; 1994 May; 45(5):932-43. PubMed ID: 8190109
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice.
    Agrawal S; Temsamani J; Tang JY
    Proc Natl Acad Sci U S A; 1991 Sep; 88(17):7595-9. PubMed ID: 1881900
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.