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4. Protective effect of a prosaposin-derived, 18-mer peptide on slowly progressive neuronal degeneration after brief ischemia. Morita F; Wen TC; Tanaka J; Hata R; Desaki J; Sato K; Nakata K; Ma YJ; Sakanaka M J Cereb Blood Flow Metab; 2001 Nov; 21(11):1295-302. PubMed ID: 11702044 [TBL] [Abstract][Full Text] [Related]
5. An 18-mer peptide fragment of prosaposin ameliorates place navigation disability, cortical infarction, and retrograde thalamic degeneration in rats with focal cerebral ischemia. Igase K; Tanaka J; Kumon Y; Zhang B; Sadamoto Y; Maeda N; Sakaki S; Sakanaka M J Cereb Blood Flow Metab; 1999 Mar; 19(3):298-306. PubMed ID: 10078882 [TBL] [Abstract][Full Text] [Related]
6. Identification of prosaposin as a neurotrophic factor. O'Brien JS; Carson GS; Seo HC; Hiraiwa M; Kishimoto Y Proc Natl Acad Sci U S A; 1994 Sep; 91(20):9593-6. PubMed ID: 7937812 [TBL] [Abstract][Full Text] [Related]
7. Identification of the neurotrophic factor sequence of prosaposin. O'Brien JS; Carson GS; Seo HC; Hiraiwa M; Weiler S; Tomich JM; Barranger JA; Kahn M; Azuma N; Kishimoto Y FASEB J; 1995 May; 9(8):681-5. PubMed ID: 7768361 [TBL] [Abstract][Full Text] [Related]
8. Ciliary neurotrophic factor prevents ischemia-induced learning disability and neuronal loss in gerbils. Wen TC; Matsuda S; Yoshimura H; Kawabe T; Sakanaka M Neurosci Lett; 1995 May; 191(1-2):55-8. PubMed ID: 7659291 [TBL] [Abstract][Full Text] [Related]
9. Induction of MAPK phosphorylation by prosaposin and prosaptide in PC12 cells. Campana WM; Hiraiwa M; Addison KC; O'Brien JS Biochem Biophys Res Commun; 1996 Dec; 229(3):706-12. PubMed ID: 8954961 [TBL] [Abstract][Full Text] [Related]
10. Prosaposin prevents programmed cell death of rat cerebellar granule neurons in culture. Tsuboi K; Hiraiwa M; O'Brien JS Brain Res Dev Brain Res; 1998 Oct; 110(2):249-55. PubMed ID: 9748612 [TBL] [Abstract][Full Text] [Related]
11. Cell death prevention, mitogen-activated protein kinase stimulation, and increased sulfatide concentrations in Schwann cells and oligodendrocytes by prosaposin and prosaptides. Hiraiwa M; Taylor EM; Campana WM; Darin SJ; O'Brien JS Proc Natl Acad Sci U S A; 1997 Apr; 94(9):4778-81. PubMed ID: 9114068 [TBL] [Abstract][Full Text] [Related]
12. Lysosomal proteolysis of prosaposin, the precursor of saposins (sphingolipid activator proteins): its mechanism and inhibition by ganglioside. Hiraiwa M; Martin BM; Kishimoto Y; Conner GE; Tsuji S; O'Brien JS Arch Biochem Biophys; 1997 May; 341(1):17-24. PubMed ID: 9143348 [TBL] [Abstract][Full Text] [Related]
13. Epidermal growth factor protects neuronal cells in vivo and in vitro against transient forebrain ischemia- and free radical-induced injuries. Peng H; Wen TC; Tanaka J; Maeda N; Matsuda S; Desaki J; Sudo S; Zhang B; Sakanaka M J Cereb Blood Flow Metab; 1998 Apr; 18(4):349-60. PubMed ID: 9538899 [TBL] [Abstract][Full Text] [Related]
14. Isolation, characterization, and proteolysis of human prosaposin, the precursor of saposins (sphingolipid activator proteins). Hiraiwa M; O'Brien JS; Kishimoto Y; Galdzicka M; Fluharty AL; Ginns EI; Martin BM Arch Biochem Biophys; 1993 Jul; 304(1):110-6. PubMed ID: 8323276 [TBL] [Abstract][Full Text] [Related]
15. Ex vivo localization of the mouse saposin C activation region for acid beta-glucosidase. Qi X; Kondoh K; Yin H; Wang M; Ponce E; Sun Y; Grabowski GA Mol Genet Metab; 2002 Jul; 76(3):189-200. PubMed ID: 12126932 [TBL] [Abstract][Full Text] [Related]
16. Colocalization and complex formation between prosaposin and monosialoganglioside GM3 in neural cells. Misasi R; Sorice M; Garofalo T; Griggi T; Campana WM; Giammatteo M; Pavan A; Hiraiwa M; Pontieri GM; O'Brien JS J Neurochem; 1998 Dec; 71(6):2313-21. PubMed ID: 9832129 [TBL] [Abstract][Full Text] [Related]
17. Prosaposin-derived peptides enhanced sprouting of sensory neurons in vitro and induced sprouting at motor endplates in vivo. Campana WM; Mohiuddin L; Misasi R; O'Brien JS; Calcutt NA J Peripher Nerv Syst; 2000 Sep; 5(3):126-30. PubMed ID: 11442168 [TBL] [Abstract][Full Text] [Related]
18. Prosaptide exacerbates ischemia-induced behavioral deficits in vivo; an effect that does not involve mitogen-activated protein kinase activation. Lapchak PA; Araujo DM; Shackelford DA; Zivin JA Neuroscience; 2000; 101(4):811-4. PubMed ID: 11113331 [TBL] [Abstract][Full Text] [Related]
19. Prosaposin receptor: evidence for a G-protein-associated receptor. Hiraiwa M; Campana WM; Martin BM; O'Brien JS Biochem Biophys Res Commun; 1997 Nov; 240(2):415-8. PubMed ID: 9388493 [TBL] [Abstract][Full Text] [Related]