BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 8791779)

  • 1. Genetic tests which identify the principal defects in CYP2C19 responsible for the polymorphism in mephenytoin metabolism.
    Goldstein JA; Blaisdell J
    Methods Enzymol; 1996; 272():210-8. PubMed ID: 8791779
    [No Abstract]   [Full Text] [Related]  

  • 2. CYP2C19 genotype and S-mephenytoin 4'-hydroxylation phenotype in a Chinese Dai population.
    He N; Yan FX; Huang SL; Wang W; Xiao ZS; Liu ZQ; Zhou HH
    Eur J Clin Pharmacol; 2002 Apr; 58(1):15-8. PubMed ID: 11956668
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bantu Tanzanians have a decreased capacity to metabolize omeprazole and mephenytoin in relation to their CYP2C19 genotype.
    Herrlin K; Massele AY; Jande M; Alm C; Tybring G; Abdi YA; Wennerholm A; Johansson I; Dahl ML; Bertilsson L; Gustafsson LL
    Clin Pharmacol Ther; 1998 Oct; 64(4):391-401. PubMed ID: 9797796
    [TBL] [Abstract][Full Text] [Related]  

  • 4. S-mephenytoin hydroxylation phenotype and CYP2C19 genotype among Ethiopians.
    Persson I; Aklillu E; Rodrigues F; Bertilsson L; Ingelman-Sundberg M
    Pharmacogenetics; 1996 Dec; 6(6):521-6. PubMed ID: 9014201
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phenotyping of CYP2C19 with enantiospecific HPLC-quantification of R- and S-mephenytoin and comparison with the intron4/exon5 G-->A-splice site mutation.
    Brockmöller J; Rost KL; Gross D; Schenkel A; Roots I
    Pharmacogenetics; 1995 Apr; 5(2):80-8. PubMed ID: 7663532
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Frequencies of defective CYP2C19 alleles in a Hong Kong Chinese population: detection of the rare allele CYP2C19*4.
    Garcia-Barceló M; Chow LY; Kum Chiu HF; Wing YK; Shing Lee DT; Lam KL; Waye MM
    Clin Chem; 1999 Dec; 45(12):2273-4. PubMed ID: 10585366
    [No Abstract]   [Full Text] [Related]  

  • 7. An additional defective allele, CYP2C19*5, contributes to the S-mephenytoin poor metabolizer phenotype in Caucasians.
    Ibeanu GC; Blaisdell J; Ghanayem BI; Beyeler C; Benhamou S; Bouchardy C; Wilkinson GR; Dayer P; Daly AK; Goldstein JA
    Pharmacogenetics; 1998 Apr; 8(2):129-35. PubMed ID: 10022751
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel transversion in the intron 5 donor splice junction of CYP2C19 and a sequence polymorphism in exon 3 contribute to the poor metabolizer phenotype for the anticonvulsant drug S-mephenytoin.
    Ibeanu GC; Blaisdell J; Ferguson RJ; Ghanayem BI; Brosen K; Benhamou S; Bouchardy C; Wilkinson GR; Dayer P; Goldstein JA
    J Pharmacol Exp Ther; 1999 Aug; 290(2):635-40. PubMed ID: 10411572
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vivo and in vitro measurement of CYP2C19 activity.
    Wedlund PJ; Wilkinson GR
    Methods Enzymol; 1996; 272():105-14. PubMed ID: 8791767
    [No Abstract]   [Full Text] [Related]  

  • 10. A new genetic defect in human CYP2C19: mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin.
    Ferguson RJ; De Morais SM; Benhamou S; Bouchardy C; Blaisdell J; Ibeanu G; Wilkinson GR; Sarich TC; Wright JM; Dayer P; Goldstein JA
    J Pharmacol Exp Ther; 1998 Jan; 284(1):356-61. PubMed ID: 9435198
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A multifamily study on the relationship between CYP2C19 genotype and s-mephenytoin oxidation phenotype.
    Brøsen K; de Morais SM; Meyer UA; Goldstein JA
    Pharmacogenetics; 1995 Oct; 5(5):312-7. PubMed ID: 8563772
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans.
    de Morais SM; Wilkinson GR; Blaisdell J; Nakamura K; Meyer UA; Goldstein JA
    J Biol Chem; 1994 Jun; 269(22):15419-22. PubMed ID: 8195181
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of new human CYP2C19 alleles (CYP2C19*6 and CYP2C19*2B) in a Caucasian poor metabolizer of mephenytoin.
    Ibeanu GC; Goldstein JA; Meyer U; Benhamou S; Bouchardy C; Dayer P; Ghanayem BI; Blaisdell J
    J Pharmacol Exp Ther; 1998 Sep; 286(3):1490-5. PubMed ID: 9732415
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phenotypic-genotypic analysis of CYP2C19 in the Jewish Israeli population.
    Sviri S; Shpizen S; Leitersdorf E; Levy M; Caraco Y
    Clin Pharmacol Ther; 1999 Mar; 65(3):275-82. PubMed ID: 10096259
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The hydroxylation of omeprazole correlates with S-mephenytoin metabolism: a population study.
    Balian JD; Sukhova N; Harris JW; Hewett J; Pickle L; Goldstein JA; Woosley RL; Flockhart DA
    Clin Pharmacol Ther; 1995 Jun; 57(6):662-9. PubMed ID: 7781266
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Individual and ethnic differences in CYP2C19 activity in Chinese populations.
    Shu Y; Zhou HH
    Acta Pharmacol Sin; 2000 Mar; 21(3):193-9. PubMed ID: 11324414
    [No Abstract]   [Full Text] [Related]  

  • 17. Genetic analysis of the S-mephenytoin polymorphism in a Chinese population.
    de Morais SM; Goldstein JA; Xie HG; Huang SL; Lu YQ; Xia H; Xiao ZS; Ile N; Zhou HH
    Clin Pharmacol Ther; 1995 Oct; 58(4):404-11. PubMed ID: 7586932
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic variations of S-mephenytoin 4'-hydroxylase (CYP2C19) in the Chinese population.
    Xie HG
    Life Sci; 2000 Feb; 66(14):PL175-81. PubMed ID: 10755474
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Association of polymorphisms in the cytochrome P450 (CYP) 2C19 and 2C18 genes in Japanese epileptic patients.
    Mamiya K; Ieiri I; Miyahara S; Imai J; Furuumi H; Fukumaki Y; Ninomiya H; Tashiro N; Yamada H; Higuchi S
    Pharmacogenetics; 1998 Feb; 8(1):87-90. PubMed ID: 9511186
    [No Abstract]   [Full Text] [Related]  

  • 20. A methodological investigation on the estimation of the S-mephenytoin hydroxylation phenotype using the urinary S/R ratio.
    Tybring G; Bertilsson L
    Pharmacogenetics; 1992 Oct; 2(5):241-3. PubMed ID: 1306124
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.