222 related articles for article (PubMed ID: 8798383)
1. Mutation of protease domain residues Lys37-39 in human protein C inhibits activation by the thrombomodulin-thrombin complex without affecting activation by free thrombin.
Gerlitz B; Grinnell BW
J Biol Chem; 1996 Sep; 271(37):22285-8. PubMed ID: 8798383
[TBL] [Abstract][Full Text] [Related]
2. Probing the activation of protein C by the thrombin-thrombomodulin complex using structural analysis, site-directed mutagenesis, and computer modeling.
Knobe KE; Berntsdotter A; Shen L; Morser J; Dahlbäck B; Villoutreix BO
Proteins; 1999 May; 35(2):218-34. PubMed ID: 10223294
[TBL] [Abstract][Full Text] [Related]
3. Tryptophans 231 and 234 in protein C report the Ca(2+)-dependent conformational change required for activation by the thrombin-thrombomodulin complex.
Rezaie AR; Esmon CT
Biochemistry; 1995 Sep; 34(38):12221-6. PubMed ID: 7547963
[TBL] [Abstract][Full Text] [Related]
4. Mutation of Glu-80-->Lys results in a protein C mutant that no longer requires Ca2+ for rapid activation by the thrombin-thrombomodulin complex.
Rezaie AR; Mather T; Sussman F; Esmon CT
J Biol Chem; 1994 Feb; 269(5):3151-4. PubMed ID: 7906267
[TBL] [Abstract][Full Text] [Related]
5. Calcium-dependent activation of protein C by thrombin/thrombomudulin: role of negatively charged amino acids within the activation peptide of protein C.
Friedrich U; Pötzsch B; Preissner KT; Müller-Berghaus G; Ehrlich H
Thromb Haemost; 1994 Oct; 72(4):567-72. PubMed ID: 7878634
[TBL] [Abstract][Full Text] [Related]
6. Amino acids 225-235** of the protein C serine-protease domain are important for the interaction with the thrombin-thrombomodulin complex.
Vincenot A; Gaussem P; Pittet JL; Debost S; Aiach M
FEBS Lett; 1995 Jun; 367(2):153-7. PubMed ID: 7540990
[TBL] [Abstract][Full Text] [Related]
7. Identification of a region in protein C involved in thrombomodulin-stimulated activation by thrombin: potential repulsion at anion-binding site I in thrombin.
Grinnell BW; Gerlitz B; Berg DT
Biochem J; 1994 Nov; 303 ( Pt 3)(Pt 3):929-33. PubMed ID: 7980464
[TBL] [Abstract][Full Text] [Related]
8. The function of calcium in protein C activation by thrombin and the thrombin-thrombomodulin complex can be distinguished by mutational analysis of protein C derivatives.
Rezaie AR; Esmon CT
J Biol Chem; 1992 Dec; 267(36):26104-9. PubMed ID: 1334492
[TBL] [Abstract][Full Text] [Related]
9. Role of Gly197 in the structure and function of protein C.
Lu Y; Biswas I; Villoutreix BO; Rezaie AR
Biochim Biophys Acta Gen Subj; 2021 Jun; 1865(6):129892. PubMed ID: 33722640
[TBL] [Abstract][Full Text] [Related]
10. Calcium-binding sites of the thrombin-thrombomodulin-protein C complex: possible implications for the effect of platelet factor 4 on the activation of vitamin K-dependent coagulation factors.
Yang L; Rezaie AR
Thromb Haemost; 2007 Jun; 97(6):899-906. PubMed ID: 17549291
[TBL] [Abstract][Full Text] [Related]
11. Occupancy of anion binding exosite 2 on thrombin determines Ca2+ dependence of protein C activation.
Liu LW; Rezaie AR; Carson CW; Esmon NL; Esmon CT
J Biol Chem; 1994 Apr; 269(16):11807-12. PubMed ID: 8163479
[TBL] [Abstract][Full Text] [Related]
12. Thrombomodulin allosterically modulates the activity of the anticoagulant thrombin.
Rezaie AR; Yang L
Proc Natl Acad Sci U S A; 2003 Oct; 100(21):12051-6. PubMed ID: 14523228
[TBL] [Abstract][Full Text] [Related]
13. Characterization of a thrombomodulin binding site on protein C and its comparison to an activated protein C binding site for factor Va.
Gale AJ; Griffin JH
Proteins; 2004 Feb; 54(3):433-41. PubMed ID: 14747992
[TBL] [Abstract][Full Text] [Related]
14. Thrombin interacts with thrombomodulin, protein C, and thrombin-activatable fibrinolysis inhibitor via specific and distinct domains.
Hall SW; Nagashima M; Zhao L; Morser J; Leung LL
J Biol Chem; 1999 Sep; 274(36):25510-6. PubMed ID: 10464282
[TBL] [Abstract][Full Text] [Related]
15. Glycosaminoglycan contributions to both protein C activation and thrombin inhibition involve a common arginine-rich site in thrombin that includes residues arginine 93, 97, and 101.
Ye J; Rezaie AR; Esmon CT
J Biol Chem; 1994 Jul; 269(27):17965-70. PubMed ID: 8027055
[TBL] [Abstract][Full Text] [Related]
16. Mutations in the fourth EGF-like domain affect thrombomodulin-induced changes in the active site of thrombin.
Koeppe JR; Beach MA; Baerga-Ortiz A; Kerns SJ; Komives EA
Biochemistry; 2008 Oct; 47(41):10933-9. PubMed ID: 18803401
[TBL] [Abstract][Full Text] [Related]
17. Recombinant human soluble thrombomodulin delivers bounded thrombin to antithrombin III: thrombomodulin associates with free thrombin and is recycled to activate protein c.
Aritomi M; Watanabe N; Ohishi R; Gomi K; Kiyota T; Yamamoto S; Ishida T; Maruyama I
Thromb Haemost; 1993 Sep; 70(3):418-22. PubMed ID: 8259541
[TBL] [Abstract][Full Text] [Related]
18. Mutagenesis studies toward understanding the mechanism of the cofactor function of thrombomodulin.
Rezaie AR; Yang L
Biophys Chem; 2005 Oct; 117(3):255-61. PubMed ID: 15970373
[TBL] [Abstract][Full Text] [Related]
19. Glycosylation of human protein C affects its secretion, processing, functional activities, and activation by thrombin.
Grinnell BW; Walls JD; Gerlitz B
J Biol Chem; 1991 May; 266(15):9778-85. PubMed ID: 2033065
[TBL] [Abstract][Full Text] [Related]
20. The Gla26 residue of protein C is required for the binding of protein C to thrombomodulin and endothelial cell protein C receptor, but not to protein S and factor Va.
Nishioka J; Ido M; Hayashi T; Suzuki K
Thromb Haemost; 1996 Feb; 75(2):275-82. PubMed ID: 8815576
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]