These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 8798677)

  • 1. The pleckstrin homology domain is the principal link between the insulin receptor and IRS-1.
    Yenush L; Makati KJ; Smith-Hall J; Ishibashi O; Myers MG; White MF
    J Biol Chem; 1996 Sep; 271(39):24300-6. PubMed ID: 8798677
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulin.
    Yenush L; Zanella C; Uchida T; Bernal D; White MF
    Mol Cell Biol; 1998 Nov; 18(11):6784-94. PubMed ID: 9774692
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro binding and phosphorylation of insulin receptor substrate 1 by the insulin receptor. Role of interactions mediated by the phosphotyrosine-binding domain and the pleckstrin-homology domain.
    Backer JM; Wjasow C; Zhang Y
    Eur J Biochem; 1997 Apr; 245(1):91-6. PubMed ID: 9128728
    [TBL] [Abstract][Full Text] [Related]  

  • 4. YMXM motifs and signaling by an insulin receptor substrate 1 molecule without tyrosine phosphorylation sites.
    Myers MG; Zhang Y; Aldaz GA; Grammer T; Glasheen EM; Yenush L; Wang LM; Sun XJ; Blenis J; Pierce JH; White MF
    Mol Cell Biol; 1996 Aug; 16(8):4147-55. PubMed ID: 8754813
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel insulin receptor substrate protein, xIRS-u, potentiates insulin signaling: functional importance of its pleckstrin homology domain.
    Ohan N; Bayaa M; Kumar P; Zhu L; Liu XJ
    Mol Endocrinol; 1998 Aug; 12(8):1086-98. PubMed ID: 9717835
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of a NPXY motif in growth factor receptor-bound protein 14 (Grb14) and its interaction with the phosphotyrosine-binding (PTB) domain of IRS-1.
    Rajala RV; Chan MD
    Biochemistry; 2005 Jun; 44(22):7929-35. PubMed ID: 15924411
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insulin receptor substrate-2 binds to the insulin receptor through its phosphotyrosine-binding domain and through a newly identified domain comprising amino acids 591-786.
    Sawka-Verhelle D; Tartare-Deckert S; White MF; Van Obberghen E
    J Biol Chem; 1996 Mar; 271(11):5980-3. PubMed ID: 8626379
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin-independent and wortmannin-resistant targeting of IRS-3 to the plasma membrane via its pleckstrin homology domain mediates a different interaction with the insulin receptor from that of IRS-1.
    Kaburagi Y; Satoh S; Yamamoto-Honda R; Ito T; Ueki K; Akanuma Y; Sekihara H; Kimura S; Kadowaki T
    Diabetologia; 2001 Aug; 44(8):992-1004. PubMed ID: 11484076
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis.
    Yenush L; Fernandez R; Myers MG; Grammer TC; Sun XJ; Blenis J; Pierce JH; Schlessinger J; White MF
    Mol Cell Biol; 1996 May; 16(5):2509-17. PubMed ID: 8628319
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor.
    Eck MJ; Dhe-Paganon S; Trüb T; Nolte RT; Shoelson SE
    Cell; 1996 May; 85(5):695-705. PubMed ID: 8646778
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The pleckstrin homology domain in insulin receptor substrate-1 sensitizes insulin signaling.
    Myers MG; Grammer TC; Brooks J; Glasheen EM; Wang LM; Sun XJ; Blenis J; Pierce JH; White MF
    J Biol Chem; 1995 May; 270(20):11715-8. PubMed ID: 7744813
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Adenovirus-mediated overexpression of IRS-1 interacting domains abolishes insulin-stimulated mitogenesis without affecting glucose transport in 3T3-L1 adipocytes.
    Sharma PM; Egawa K; Gustafson TA; Martin JL; Olefsky JM
    Mol Cell Biol; 1997 Dec; 17(12):7386-97. PubMed ID: 9372969
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Heterologous pleckstrin homology domains do not couple IRS-1 to the insulin receptor.
    Burks DJ; Pons S; Towery H; Smith-Hall J; Myers MG; Yenush L; White MF
    J Biol Chem; 1997 Oct; 272(44):27716-21. PubMed ID: 9346913
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities.
    Wolf G; Trüb T; Ottinger E; Groninga L; Lynch A; White MF; Miyazaki M; Lee J; Shoelson SE
    J Biol Chem; 1995 Nov; 270(46):27407-10. PubMed ID: 7499194
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Deletion of the pleckstrin and phosphotyrosine binding domains of insulin receptor substrate-2 does not impair its ability to regulate cell proliferation in myeloid cells.
    Sun H; Baserga R
    Endocrinology; 2004 Nov; 145(11):5332-43. PubMed ID: 15297443
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain.
    Ogihara T; Isobe T; Ichimura T; Taoka M; Funaki M; Sakoda H; Onishi Y; Inukai K; Anai M; Fukushima Y; Kikuchi M; Yazaki Y; Oka Y; Asano T
    J Biol Chem; 1997 Oct; 272(40):25267-74. PubMed ID: 9312143
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insulin receptor substrate-1 mediates phosphatidylinositol 3'-kinase and p70S6k signaling during insulin, insulin-like growth factor-1, and interleukin-4 stimulation.
    Myers MG; Grammer TC; Wang LM; Sun XJ; Pierce JH; Blenis J; White MF
    J Biol Chem; 1994 Nov; 269(46):28783-9. PubMed ID: 7961833
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Insulin receptor substrate-1 enhances growth hormone-induced proliferation.
    Liang L; Zhou T; Jiang J; Pierce JH; Gustafson TA; Frank SJ
    Endocrinology; 1999 May; 140(5):1972-83. PubMed ID: 10218944
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Re-engineering the target specificity of the insulin receptor by modification of a PTB domain binding site.
    van der Geer P; Wiley S; Pawson T
    Oncogene; 1999 May; 18(20):3071-5. PubMed ID: 10340378
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Different pathways of postreceptor desensitization following chronic insulin treatment and in cells overexpressing constitutively active insulin receptors.
    Inoue G; Cheatham B; Kahn CR
    J Biol Chem; 1996 Nov; 271(45):28206-11. PubMed ID: 8910437
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.