BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

352 related articles for article (PubMed ID: 8805583)

  • 1. Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous beta-sheet helix.
    Blake C; Serpell L
    Structure; 1996 Aug; 4(8):989-98. PubMed ID: 8805583
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analysis of x-ray diffraction patterns from amyloid of biopsied vitreous humor and kidney of transthyretin (TTR) Met30 familial amyloidotic polyneuropathy (FAP) patients: axially arrayed TTR monomers constitute the protofilament.
    Inouye H; Domingues FS; Damas AM; Saraiva MJ; Lundgren E; Sandgren O; Kirschner DA
    Amyloid; 1998 Sep; 5(3):163-74. PubMed ID: 9818053
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A molecular model of the amyloid fibril.
    Blake CC; Serpell LC; Sunde M; Sandgren O; Lundgren E
    Ciba Found Symp; 1996; 199():6-15; discussion 15-21, 40-6. PubMed ID: 8915601
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Common core structure of amyloid fibrils by synchrotron X-ray diffraction.
    Sunde M; Serpell LC; Bartlam M; Fraser PE; Pepys MB; Blake CC
    J Mol Biol; 1997 Oct; 273(3):729-39. PubMed ID: 9356260
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transthyretin fibrillogenesis entails the assembly of monomers: a molecular model for in vitro assembled transthyretin amyloid-like fibrils.
    Cardoso I; Goldsbury CS; Müller SA; Olivieri V; Wirtz S; Damas AM; Aebi U; Saraiva MJ
    J Mol Biol; 2002 Apr; 317(5):683-95. PubMed ID: 11955017
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The most pathogenic transthyretin variant, L55P, forms amyloid fibrils under acidic conditions and protofilaments under physiological conditions.
    Lashuel HA; Wurth C; Woo L; Kelly JW
    Biochemistry; 1999 Oct; 38(41):13560-73. PubMed ID: 10521263
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Experimentally derived structural constraints for amyloid fibrils of wild-type transthyretin.
    Bateman DA; Tycko R; Wickner RB
    Biophys J; 2011 Nov; 101(10):2485-92. PubMed ID: 22098747
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The protofilament substructure of amyloid fibrils.
    Serpell LC; Sunde M; Benson MD; Tennent GA; Pepys MB; Fraser PE
    J Mol Biol; 2000 Jul; 300(5):1033-9. PubMed ID: 10903851
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro modelling of familial amyloidotic polyneuropathy allows quantitative detection of transthyretin amyloid fibril-like structures in hepatic derivatives of patient-specific induced pluripotent stem cells.
    Hoepfner J; Kleinsorge M; Papp O; Alfken S; Heiringhoff R; Pich A; Sauer V; Zibert A; Göhring G; Schmidt H; Sgodda M; Cantz T
    Biol Chem; 2017 Jul; 398(8):939-954. PubMed ID: 28051995
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Partial denaturation of transthyretin is sufficient for amyloid fibril formation in vitro.
    Colon W; Kelly JW
    Biochemistry; 1992 Sep; 31(36):8654-60. PubMed ID: 1390650
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing.
    Jiménez JL; Guijarro JI; Orlova E; Zurdo J; Dobson CM; Sunde M; Saibil HR
    EMBO J; 1999 Feb; 18(4):815-21. PubMed ID: 10022824
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Examination of the structure of the transthyretin amyloid fibril by image reconstruction from electron micrographs.
    Serpell LC; Sunde M; Fraser PE; Luther PK; Morris EP; Sangren O; Lundgren E; Blake CC
    J Mol Biol; 1995 Nov; 254(2):113-8. PubMed ID: 7490736
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dissociation of amyloid fibrils of alpha-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities.
    Foguel D; Suarez MC; Ferrão-Gonzales AD; Porto TC; Palmieri L; Einsiedler CM; Andrade LR; Lashuel HA; Lansbury PT; Kelly JW; Silva JL
    Proc Natl Acad Sci U S A; 2003 Aug; 100(17):9831-6. PubMed ID: 12900507
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FTIR reveals structural differences between native beta-sheet proteins and amyloid fibrils.
    Zandomeneghi G; Krebs MR; McCammon MG; Fändrich M
    Protein Sci; 2004 Dec; 13(12):3314-21. PubMed ID: 15537750
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of the transthyretin acid denaturation pathways by analytical ultracentrifugation: implications for wild-type, V30M, and L55P amyloid fibril formation.
    Lashuel HA; Lai Z; Kelly JW
    Biochemistry; 1998 Dec; 37(51):17851-64. PubMed ID: 9922152
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tetramer dissociation and monomer partial unfolding precedes protofibril formation in amyloidogenic transthyretin variants.
    Quintas A; Vaz DC; Cardoso I; Saraiva MJ; Brito RM
    J Biol Chem; 2001 Jul; 276(29):27207-13. PubMed ID: 11306576
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The tetrameric protein transthyretin dissociates to a non-native monomer in solution. A novel model for amyloidogenesis.
    Quintas A; Saraiva MJ; Brito RM
    J Biol Chem; 1999 Nov; 274(46):32943-9. PubMed ID: 10551861
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High-resolution molecular structure of a peptide in an amyloid fibril determined by magic angle spinning NMR spectroscopy.
    Jaroniec CP; MacPhee CE; Bajaj VS; McMahon MT; Dobson CM; Griffin RG
    Proc Natl Acad Sci U S A; 2004 Jan; 101(3):711-6. PubMed ID: 14715898
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparison of lethal and nonlethal transthyretin variants and their relationship to amyloid disease.
    McCutchen SL; Lai Z; Miroy GJ; Kelly JW; Colón W
    Biochemistry; 1995 Oct; 34(41):13527-36. PubMed ID: 7577941
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ultrastructure of familial amyloid polyneuropathy amyloid fibrils: examination with high-resolution electron microscopy.
    Inoue S; Kuroiwa M; Saraiva MJ; Guimarães A; Kisilevsky R
    J Struct Biol; 1998 Dec; 124(1):1-12. PubMed ID: 9931270
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.