BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 8806703)

  • 1. Expression and characterization of human pancreatic preprocarboxypeptidase A1 and preprocarboxypeptidase A2.
    Laethem RM; Blumenkopf TA; Cory M; Elwell L; Moxham CP; Ray PH; Walton LM; Smith GK
    Arch Biochem Biophys; 1996 Aug; 332(1):8-18. PubMed ID: 8806703
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Toward antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1 and novel in vivo stable prodrugs of methotrexate.
    Smith GK; Banks S; Blumenkopf TA; Cory M; Humphreys J; Laethem RM; Miller J; Moxham CP; Mullin R; Ray PH; Walton LM; Wolfe LA
    J Biol Chem; 1997 Jun; 272(25):15804-16. PubMed ID: 9188478
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1: in vitro and in vivo studies with prodrugs of methotrexate and the thymidylate synthase inhibitors GW1031 and GW1843.
    Wolfe LA; Mullin RJ; Laethem R; Blumenkopf TA; Cory M; Miller JF; Keith BR; Humphreys J; Smith GK
    Bioconjug Chem; 1999; 10(1):38-48. PubMed ID: 9893962
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Methotrexate-alpha-phenylalanine: optimization of methotrexate prodrug for activation by carboxypeptidase A-monoclonal antibody conjugate.
    Vitols KS; Haag-Zeino B; Baer T; Montejano YD; Huennekens FM
    Cancer Res; 1995 Feb; 55(3):478-81. PubMed ID: 7834611
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of the prodomain in folding and secretion of rat pancreatic carboxypeptidase A1.
    Phillips MA; Rutter WJ
    Biochemistry; 1996 May; 35(21):6771-6. PubMed ID: 8639628
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Specific tumour localisation of a huA33 antibody--carboxypeptidase A conjugate and activation of methotrexate-phenylalanine.
    Deckert PM; Bornmann WG; Ritter G; Williams C; Franke J; Keilholz U; Thiel E; Old LJ; Bertino JR; Welt S
    Int J Oncol; 2004 May; 24(5):1289-95. PubMed ID: 15067353
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vitro and in vivo prodrug therapy of prostate cancer using anti-gamma-Sm-scFv/hCPA fusion protein.
    Hao XK; Liu JY; Yue QH; Wu GJ; Bai YJ; Yin Y
    Prostate; 2006 Jun; 66(8):858-66. PubMed ID: 16491483
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cloning, sequencing and functional expression of a cDNA encoding porcine pancreatic preprocarboxypeptidase A1.
    Darnis S; Juge N; Marino C; Avilés FX; Puigserver A; Chaix JC; Guo XJ
    Eur J Biochem; 1999 Feb; 259(3):719-25. PubMed ID: 10092856
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cloning, sequencing and expression of the gene encoding a major allotypic preprocarboxypeptidase A from bovine pancreas.
    Goo JH; Kim KH; Choi KY
    Gene; 1995 Nov; 165(2):333-4. PubMed ID: 8522204
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cloning, sequence, expression and characterization of human beta-mannosidase.
    Samra ZQ; Athar MA
    Acta Biochim Pol; 2008; 55(3):479-90. PubMed ID: 18800177
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cloning and nucleotide sequence of a bovine pancreatic preprocarboxypeptidase A cDNA.
    Le Huërou I; Guilloteau P; Toullec R; Puigserver A; Wicker C
    Biochem Biophys Res Commun; 1991 Feb; 175(1):110-6. PubMed ID: 1998496
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal structure and mechanism of human carboxypeptidase O: Insights into its specific activity for acidic residues.
    Garcia-Guerrero MC; Garcia-Pardo J; Berenguer E; Fernandez-Alvarez R; Barfi GB; Lyons PJ; Aviles FX; Huber R; Lorenzo J; Reverter D
    Proc Natl Acad Sci U S A; 2018 Apr; 115(17):E3932-E3939. PubMed ID: 29636417
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evolution of lactate dehydrogenase-A homologs of barracuda fishes (genus Sphyraena) from different thermal environments: differences in kinetic properties and thermal stability are due to amino acid substitutions outside the active site.
    Holland LZ; McFall-Ngai M; Somero GN
    Biochemistry; 1997 Mar; 36(11):3207-15. PubMed ID: 9115998
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The sequence and conformation of human pancreatic procarboxypeptidase A2. cDNA cloning, sequence analysis, and three-dimensional model.
    Catasús L; Vendrell J; Avilés FX; Carreira S; Puigserver A; Billeter M
    J Biol Chem; 1995 Mar; 270(12):6651-7. PubMed ID: 7896805
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Purification and characterization of recombinant human cathepsin E expressed in human kidney cell line 293.
    Cappiello MG; Wu Z; Scott BB; McGeehan GM; Harrison RK
    Protein Expr Purif; 2004 Sep; 37(1):53-60. PubMed ID: 15294281
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ostrich (Struthio camelus) carboxypeptidase A: purification, kinetic properties and characterization of the pancreatic enzyme.
    Bradley G; Naudé RJ; Muramoto K; Yamauchi F; Oelofsen W
    Int J Biochem; 1994 Apr; 26(4):555-64. PubMed ID: 8013741
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rat preprocarboxypeptidase A: cDNA sequence and preliminary characterization of the gene.
    Quinto C; Quiroga M; Swain WF; Nikovits WC; Standring DN; Pictet RL; Valenzuela P; Rutter WJ
    Proc Natl Acad Sci U S A; 1982 Jan; 79(1):31-5. PubMed ID: 6275388
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proteome-derived peptide libraries to study the substrate specificity profiles of carboxypeptidases.
    Tanco S; Lorenzo J; Garcia-Pardo J; Degroeve S; Martens L; Aviles FX; Gevaert K; Van Damme P
    Mol Cell Proteomics; 2013 Aug; 12(8):2096-110. PubMed ID: 23620545
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural determinants of glutathione transferases with azathioprine activity identified by DNA shuffling of alpha class members.
    Kurtovic S; Modén O; Shokeer A; Mannervik B
    J Mol Biol; 2008 Feb; 375(5):1365-79. PubMed ID: 18155239
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel rat carboxypeptidase, CPA2: characterization, molecular cloning, and evolutionary implications on substrate specificity in the carboxypeptidase gene family.
    Gardell SJ; Craik CS; Clauser E; Goldsmith EJ; Stewart CB; Graf M; Rutter WJ
    J Biol Chem; 1988 Nov; 263(33):17828-36. PubMed ID: 3182871
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.