BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 8809060)

  • 1. Efficacy of agonist-stimulated MEK activation determines the susceptibility of mitogen-activated protein (MAP) kinase to inhibition in rat aortic smooth muscle cells.
    Plevin R; Scott PH; Robinson CJ; Gould GW
    Biochem J; 1996 Sep; 318 ( Pt 2)(Pt 2):657-63. PubMed ID: 8809060
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cyclic AMP inhibitors inhibits PDGF-stimulated mitogen-activated protein kinase activity in rat aortic smooth muscle cells via inactivation of c-Raf-1 kinase and induction of MAP kinase phosphatase-1.
    Plevin R; Malarkey K; Aidulis D; McLees A; Gould GW
    Cell Signal; 1997; 9(3-4):323-8. PubMed ID: 9218135
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MEK inhibition augments Raf activity, but has variable effects on mitogenesis, in vascular smooth muscle cells.
    Weiss RH; Maga EA; Ramirez A
    Am J Physiol; 1998 Jun; 274(6):C1521-9. PubMed ID: 9696694
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MEK1 is required for PDGF-induced ERK activation and DNA synthesis in tracheal myocytes.
    Karpova AY; Abe MK; Li J; Liu PT; Rhee JM; Kuo WL; Hershenson MB
    Am J Physiol; 1997 Mar; 272(3 Pt 1):L558-65. PubMed ID: 9124614
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A regulatory role for cAMP in phosphatidylinositol 3-kinase/p70 ribosomal S6 kinase-mediated DNA synthesis in platelet-derived-growth-factor-stimulated bovine airway smooth-muscle cells.
    Scott PH; Belham CM; al-Hafidh J; Chilvers ER; Peacock AJ; Gould GW; Plevin R
    Biochem J; 1996 Sep; 318 ( Pt 3)(Pt 3):965-71. PubMed ID: 8836145
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A dominant role for the Raf-MEK pathway in forskolin, 12-O-tetradecanoyl-phorbol acetate, and platelet-derived growth factor-induced CREB (cAMP-responsive element-binding protein) activation, uncoupled from serine 133 phosphorylation in NIH 3T3 cells.
    Seternes OM; Johansen B; Moens U
    Mol Endocrinol; 1999 Jul; 13(7):1071-83. PubMed ID: 10406459
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Angiotensin II stimulates MAP kinase kinase kinase activity in vascular smooth muscle cells, Role of Raf.
    Liao DF; Duff JL; Daum G; Pelech SL; Berk BC
    Circ Res; 1996 Nov; 79(5):1007-14. PubMed ID: 8888693
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stimulation by endothelin-1 of mitogen-activated protein kinases and DNA synthesis in bovine tracheal smooth muscle cells.
    Malarkey K; Chilvers ER; Lawson MF; Plevin R
    Br J Pharmacol; 1995 Oct; 116(4):2267-73. PubMed ID: 8564258
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of protein kinase C in activation and termination of mitogen-activated protein kinase activity in angiotensin II-stimulated rat aortic smooth-muscle cells.
    Malarkey K; McLees A; Paul A; Gould GW; Plevin R
    Cell Signal; 1996 Feb; 8(2):123-9. PubMed ID: 8730514
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tumour necrosis factor-alpha enhances bradykinin-induced signal transduction via activation of Ras/Raf/MEK/MAPK in canine tracheal smooth muscle cells.
    Hsu YM; Chiu CT; Wang CC; Chien CS; Luo SF; Hsiao LD; Liang KY; Yang CM
    Cell Signal; 2001 Sep; 13(9):633-43. PubMed ID: 11495721
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanisms of inhibition by heparin of PDGF stimulated MAP kinase activation in vascular smooth muscle cells.
    Pukac LA; Carter JE; Ottlinger ME; Karnovsky MJ
    J Cell Physiol; 1997 Jul; 172(1):69-78. PubMed ID: 9207927
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases.
    Belham CM; Tate RJ; Scott PH; Pemberton AD; Miller HR; Wadsworth RM; Gould GW; Plevin R
    Biochem J; 1996 Dec; 320 ( Pt 3)(Pt 3):939-46. PubMed ID: 9003384
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of growth factor-induced protein synthesis by a selective MEK inhibitor in aortic smooth muscle cells.
    Servant MJ; Giasson E; Meloche S
    J Biol Chem; 1996 Jul; 271(27):16047-52. PubMed ID: 8663242
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lactosylceramide stimulates Ras-GTP loading, kinases (MEK, Raf), p44 mitogen-activated protein kinase, and c-fos expression in human aortic smooth muscle cells.
    Bhunia AK; Han H; Snowden A; Chatterjee S
    J Biol Chem; 1996 May; 271(18):10660-6. PubMed ID: 8631872
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rat aortic smooth muscle cell density affects activation of MAP kinase and Akt by menadione and PDGF homodimer BB.
    Li XA; Bianchi C; Sellke FW
    J Surg Res; 2001 Oct; 100(2):197-204. PubMed ID: 11592793
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Platelet-derived growth factor-BB and thrombin activate phosphoinositide 3-kinase and protein kinase B: role in mediating airway smooth muscle proliferation.
    Walker TR; Moore SM; Lawson MF; Panettieri RA; Chilvers ER
    Mol Pharmacol; 1998 Dec; 54(6):1007-15. PubMed ID: 9855629
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitogen-activated protein kinase activation is involved in platelet-derived growth factor-directed migration by vascular smooth muscle cells.
    Graf K; Xi XP; Yang D; Fleck E; Hsueh WA; Law RE
    Hypertension; 1997 Jan; 29(1 Pt 2):334-9. PubMed ID: 9039124
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lipopolysaccharide enhances bradykinin-induced signal transduction via activation of Ras/Raf/MEK/MAPK in canine tracheal smooth muscle cells.
    Luo SF; Wang CC; Chiu CT; Chien CS; Hsiao LD; Lin CH; Yang CM
    Br J Pharmacol; 2000 Aug; 130(8):1799-808. PubMed ID: 10952668
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Angiotensin II type 1 receptor signals through Raf-1 by a protein kinase C-dependent, Ras-independent mechanism.
    Arai H; Escobedo JA
    Mol Pharmacol; 1996 Sep; 50(3):522-8. PubMed ID: 8794890
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic.
    Tombes RM; Auer KL; Mikkelsen R; Valerie K; Wymann MP; Marshall CJ; McMahon M; Dent P
    Biochem J; 1998 Mar; 330 ( Pt 3)(Pt 3):1451-60. PubMed ID: 9494119
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.