109 related articles for article (PubMed ID: 8809151)
1. Evaluation of selected chemotypes in coupled cellular and molecular target-based screens identifies novel HIV-1 zinc finger inhibitors.
Rice WG; Turpin JA; Schaeffer CA; Graham L; Clanton D; Buckheit RW; Zaharevitz D; Summers MF; Wallqvist A; Covell DG
J Med Chem; 1996 Sep; 39(19):3606-16. PubMed ID: 8809151
[TBL] [Abstract][Full Text] [Related]
2. Anti-HIV agents that selectively target retroviral nucleocapsid protein zinc fingers without affecting cellular zinc finger proteins.
Huang M; Maynard A; Turpin JA; Graham L; Janini GM; Covell DG; Rice WG
J Med Chem; 1998 Apr; 41(9):1371-81. PubMed ID: 9554870
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological properties of novel pyridinioalkanoyl thiolesters (PATE) as anti-HIV-1 agents that target the viral nucleocapsid protein zinc fingers.
Turpin JA; Song Y; Inman JK; Huang M; Wallqvist A; Maynard A; Covell DG; Rice WG; Appella E
J Med Chem; 1999 Jan; 42(1):67-86. PubMed ID: 9888834
[TBL] [Abstract][Full Text] [Related]
4. Optimization of unique, uncharged thioesters as inhibitors of HIV replication.
Srivastava P; Schito M; Fattah RJ; Hara T; Hartman T; Buckheit RW; Turpin JA; Inman JK; Appella E
Bioorg Med Chem; 2004 Dec; 12(24):6437-50. PubMed ID: 15556761
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of HIV-1 infectivity by zinc-ejecting aromatic C-nitroso compounds.
Rice WG; Schaeffer CA; Harten B; Villinger F; South TL; Summers MF; Henderson LE; Bess JW; Arthur LO; McDougal JS
Nature; 1993 Feb; 361(6411):473-5. PubMed ID: 8429889
[TBL] [Abstract][Full Text] [Related]
6. Identification by high throughput screening of small compounds inhibiting the nucleic acid destabilization activity of the HIV-1 nucleocapsid protein.
Shvadchak V; Sanglier S; Rocle S; Villa P; Haiech J; Hibert M; Van Dorsselaer A; Mély Y; de Rocquigny H
Biochimie; 2009 Jul; 91(7):916-23. PubMed ID: 19401213
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of Friend virus replication by a compound that reacts with the nucleocapsid zinc finger: anti-retroviral effect demonstrated in vivo.
Ott DE; Hewes SM; Alvord WG; Henderson LE; Arthur LO
Virology; 1998 Apr; 243(2):283-92. PubMed ID: 9568028
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of multiple phases of human immunodeficiency virus type 1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins.
Rice WG; Baker DC; Schaeffer CA; Graham L; Bu M; Terpening S; Clanton D; Schultz R; Bader JP; Buckheit RW; Field L; Singh PK; Turpin JA
Antimicrob Agents Chemother; 1997 Feb; 41(2):419-26. PubMed ID: 9021201
[TBL] [Abstract][Full Text] [Related]
9. 2,2'-Dithiobisbenzamides and 2-benzisothiazolones, two new classes of antiretroviral agents: SAR and mechanistic considerations.
Domagala JM; Gogliotti R; Sanchez JP; Stier MA; Musa K; Song Y; Loo J; Reily M; Tummino P; Harvey P; Hupe D; Sharmeen L; Mack D; Scholten J; Saunders J; McQuade T
Drug Des Discov; 1997 May; 15(1):49-61. PubMed ID: 9332831
[TBL] [Abstract][Full Text] [Related]
10. Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling.
Artico M; Di Santo R; Costi R; Novellino E; Greco G; Massa S; Tramontano E; Marongiu ME; De Montis A; La Colla P
J Med Chem; 1998 Oct; 41(21):3948-60. PubMed ID: 9767632
[TBL] [Abstract][Full Text] [Related]
11. Strict conservation of the retroviral nucleocapsid protein zinc finger is strongly influenced by its role in viral infection processes: characterization of HIV-1 particles containing mutant nucleocapsid zinc-coordinating sequences.
Gorelick RJ; Gagliardi TD; Bosche WJ; Wiltrout TA; Coren LV; Chabot DJ; Lifson JD; Henderson LE; Arthur LO
Virology; 1999 Mar; 256(1):92-104. PubMed ID: 10087230
[TBL] [Abstract][Full Text] [Related]
12. Inhibitors of human immunodeficiency virus type 1 zinc fingers prevent normal processing of gag precursors and result in the release of noninfectious virus particles.
Turpin JA; Terpening SJ; Schaeffer CA; Yu G; Glover CJ; Felsted RL; Sausville EA; Rice WG
J Virol; 1996 Sep; 70(9):6180-9. PubMed ID: 8709244
[TBL] [Abstract][Full Text] [Related]
13. New alkenyldiarylmethanes with enhanced potencies as anti-HIV agents which act as non-nucleoside reverse transcriptase inhibitors.
Cushman M; Casimiro-Garcia A; Hejchman E; Ruell JA; Huang M; Schaeffer CA; Williamson K; Rice WG; Buckheit RW
J Med Chem; 1998 Jun; 41(12):2076-89. PubMed ID: 9622549
[TBL] [Abstract][Full Text] [Related]
14. Identification of a novel Vpr-binding compound that inhibits HIV-1 multiplication in macrophages by chemical array.
Hagiwara K; Murakami T; Xue G; Shimizu Y; Takeda E; Hashimoto Y; Honda K; Kondoh Y; Osada H; Tsunetsugu-Yokota Y; Aida Y
Biochem Biophys Res Commun; 2010 Dec; 403(1):40-5. PubMed ID: 21036153
[TBL] [Abstract][Full Text] [Related]
15. Suppression of retrovirial replication: inactivation of murine leukemia virus by compounds reacting with the zinc finger in the viral nucleocapsid protein.
Rein A; Ott DE; Mirro J; Arthur LO; Rice WG; Henderson LE
Leukemia; 1997 Apr; 11 Suppl 3():106-8. PubMed ID: 9209313
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of in vitro and in vivo HIV replication by a distamycin analogue that interferes with chemokine receptor function: a candidate for chemotherapeutic and microbicidal application.
Howard OM; Oppenheim JJ; Hollingshead MG; Covey JM; Bigelow J; McCormack JJ; Buckheit RW; Clanton DJ; Turpin JA; Rice WG
J Med Chem; 1998 Jun; 41(13):2184-93. PubMed ID: 9632350
[TBL] [Abstract][Full Text] [Related]
17. Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity.
Fattorusso C; Gemma S; Butini S; Huleatt P; Catalanotti B; Persico M; De Angelis M; Fiorini I; Nacci V; Ramunno A; Rodriquez M; Greco G; Novellino E; Bergamini A; Marini S; Coletta M; Maga G; Spadari S; Campiani G
J Med Chem; 2005 Nov; 48(23):7153-65. PubMed ID: 16279773
[TBL] [Abstract][Full Text] [Related]
18. Zinc ejection as a new rationale for the use of cystamine and related disulfide-containing antiviral agents in the treatment of AIDS.
McDonnell NB; De Guzman RN; Rice WG; Turpin JA; Summers MF
J Med Chem; 1997 Jun; 40(13):1969-76. PubMed ID: 9207937
[TBL] [Abstract][Full Text] [Related]
19. Repression of the HIV-1 5' LTR promoter and inhibition of HIV-1 replication by using engineered zinc-finger transcription factors.
Reynolds L; Ullman C; Moore M; Isalan M; West MJ; Clapham P; Klug A; Choo Y
Proc Natl Acad Sci U S A; 2003 Feb; 100(4):1615-20. PubMed ID: 12574502
[TBL] [Abstract][Full Text] [Related]
20. Abasic analogues of TSAO-T as the first sugar derivatives that specifically inhibit HIV-1 reverse transcriptase.
Velázquez S; Chamorro C; Pérez-Pérez MJ; Alvarez R; Jimeno ML; Martín-Domenech A; Pérez C; Gago F; De Clercq E; Balzarini J; San-Félix A; Camarasa MJ
J Med Chem; 1998 Nov; 41(23):4636-47. PubMed ID: 9804703
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
