BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

350 related articles for article (PubMed ID: 8812831)

  • 1. Functional expression of the dihydrofolate reductase domain of Leishmania major dihydrofolate reductase-thymidylate synthase bifunctional protein.
    Yu PL; Zhao J; Yu M; Reid R; Santi DV
    Protein Expr Purif; 1996 Aug; 8(1):23-7. PubMed ID: 8812831
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Heterologous expression and characterization of the bifunctional dihydrofolate reductase-thymidylate synthase enzyme of Toxoplasma gondii.
    Trujillo M; Donald RG; Roos DS; Greene PJ; Santi DV
    Biochemistry; 1996 May; 35(20):6366-74. PubMed ID: 8639582
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Kinetic reaction scheme for the dihydrofolate reductase domain of the bifunctional thymidylate synthase-dihydrofolate reductase from Leishmania major.
    Liang PH; Anderson KS
    Biochemistry; 1998 Sep; 37(35):12206-12. PubMed ID: 9724534
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Substrate channeling and domain-domain interactions in bifunctional thymidylate synthase-dihydrofolate reductase.
    Liang PH; Anderson KS
    Biochemistry; 1998 Sep; 37(35):12195-205. PubMed ID: 9724533
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Homology modelling of the dihydrofolate reductase-thymidylate synthase bifunctional enzyme of Leishmania major, a potential target for rational drug design in leishmaniasis.
    McKie JH
    Drug Des Discov; 1994 Jun; 11(4):269-88. PubMed ID: 7727680
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Trypanosoma brucei dihydrofolate reductase-thymidylate synthase: gene isolation and expression and characterization of the enzyme.
    Gamarro F; Yu PL; Zhao J; Edman U; Greene PJ; Santi D
    Mol Biochem Parasitol; 1995 Jun; 72(1-2):11-22. PubMed ID: 8538681
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Heterologous expression of the bifunctional thymidylate synthase-dihydrofolate reductase from Leishmania major.
    Grumont R; Sirawaraporn W; Santi DV
    Biochemistry; 1988 May; 27(10):3776-84. PubMed ID: 2841973
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cloning, expression, and characterization of Mycobacterium tuberculosis dihydrofolate reductase.
    White EL; Ross LJ; Cunningham A; Escuyer V
    FEMS Microbiol Lett; 2004 Mar; 232(1):101-5. PubMed ID: 15019741
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The dihydrofolate reductase domain of Plasmodium falciparum thymidylate synthase-dihydrofolate reductase. Gene synthesis, expression, and anti-folate-resistant mutants.
    Sirawaraporn W; Prapunwattana P; Sirawaraporn R; Yuthavong Y; Santi DV
    J Biol Chem; 1993 Oct; 268(29):21637-44. PubMed ID: 8408015
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cloning and expression of the dihydrofolate reductase-thymidylate synthase gene from Trypanosoma cruzi.
    Reche P; Arrebola R; Olmo A; Santi DV; Gonzalez-Pacanowska D; Ruiz-Perez LM
    Mol Biochem Parasitol; 1994 Jun; 65(2):247-58. PubMed ID: 7969266
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate.
    Senkovich O; Schormann N; Chattopadhyay D
    Acta Crystallogr D Biol Crystallogr; 2009 Jul; 65(Pt 7):704-16. PubMed ID: 19564691
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heterologous expression of active thymidylate synthase-dihydrofolate reductase from Plasmodium falciparum.
    Sirawaraporn W; Sirawaraporn R; Cowman AF; Yuthavong Y; Santi DV
    Biochemistry; 1990 Dec; 29(48):10779-85. PubMed ID: 2176883
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure of and kinetic channelling in bifunctional dihydrofolate reductase-thymidylate synthase.
    Knighton DR; Kan CC; Howland E; Janson CA; Hostomska Z; Welsh KM; Matthews DA
    Nat Struct Biol; 1994 Mar; 1(3):186-94. PubMed ID: 7656037
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Isolation and characterization of a mutant dihydrofolate reductase-thymidylate synthase from methotrexate-resistant Leishmania cells.
    Arrebola R; Olmo A; Reche P; Garvey EP; Santi DV; Ruiz-Perez LM; Gonzalez-Pacanowska D
    J Biol Chem; 1994 Apr; 269(14):10590-6. PubMed ID: 8144647
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Refolding of recombinant Pneumocystis carinii dihydrofolate reductase and characterization of the enzyme.
    Delves CJ; Ballantine SP; Tansik RL; Baccanari DP; Stammers DK
    Protein Expr Purif; 1993 Feb; 4(1):16-23. PubMed ID: 8425104
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Soluble expression in Escherichia coli, one-step purification, and characterization of Chinese hamster dihydrofolate reductase.
    Fan YX; Wang B; Jing GZ
    Protein Expr Purif; 1997 Mar; 9(2):246-52. PubMed ID: 9056490
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Purification of the bifunctional thymidylate synthase-dihydrofolate reductase complex from the human malaria parasite Plasmodium falciparum.
    Chen GX; Zolg JW
    Mol Pharmacol; 1987 Dec; 32(6):723-30. PubMed ID: 3320742
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Probing the role of parasite-specific, distant structural regions on communication and catalysis in the bifunctional thymidylate synthase-dihydrofolate reductase from Plasmodium falciparum.
    Dasgupta T; Anderson KS
    Biochemistry; 2008 Feb; 47(5):1336-45. PubMed ID: 18189414
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression and characterization of the Trypanosoma cruzi dihydrofolate reductase domain.
    Reche P; Arrebola R; Santi DV; Gonzalez-Pacanowska D; Ruiz-Perez LM
    Mol Biochem Parasitol; 1996; 76(1-2):175-85. PubMed ID: 8920005
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Overexpression and large-scale purification of recombinant hamster polymorphic arylamine N-acetyltransferase as a dihydrofolate reductase fusion protein.
    Sticha KR; Sieg CA; Bergstrom CP; Hanna PE; Wagner CR
    Protein Expr Purif; 1997 Jun; 10(1):141-53. PubMed ID: 9179301
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.