163 related articles for article (PubMed ID: 8819301)
1. A comparative study of precision cut liver slices, hepatocytes, and liver microsomes from the Wistar rat using metronidazole as a model substance.
Sidelmann UG; Cornett C; Tjørnelund J; Hansen SH
Xenobiotica; 1996 Jul; 26(7):709-22. PubMed ID: 8819301
[TBL] [Abstract][Full Text] [Related]
2. Metabolism of metronidazole and antipyrine in hepatocytes isolated from mouse and rat.
Loft S; Poulsen HE
Xenobiotica; 1990 Feb; 20(2):185-91. PubMed ID: 2333715
[TBL] [Abstract][Full Text] [Related]
3. Metabolism of metronidazole and antipyrine in isolated rat hepatocytes. Influence of sex and enzyme induction and inhibition.
Loft S; Poulsen HE
Biochem Pharmacol; 1989 Apr; 38(7):1125-36. PubMed ID: 2706012
[TBL] [Abstract][Full Text] [Related]
4. Comparison of the metabolism of 7-ethoxycoumarin and coumarin in precision-cut rat liver and lung slices.
Price RJ; Renwick AB; Beamand JA; Esclangon F; Wield PT; Walters DG; Lake BG
Food Chem Toxicol; 1995 Mar; 33(3):233-7. PubMed ID: 7896234
[TBL] [Abstract][Full Text] [Related]
5. Predictive value of liver slices for metabolism and toxicity in vivo: use of acetaminophen as a model hepatotoxicant.
Miller MG; Beyer J; Hall GL; deGraffenried LA; Adams PE
Toxicol Appl Pharmacol; 1993 Sep; 122(1):108-16. PubMed ID: 8378925
[TBL] [Abstract][Full Text] [Related]
6. Kinetics of drug metabolism in rat liver slices: IV. Comparison of ethoxycoumarin clearance by liver slices, isolated hepatocytes, and hepatic microsomes from rats pretreated with known modifiers of cytochrome P-450 activity.
Carlile DJ; Hakooz N; Houston JB
Drug Metab Dispos; 1999 Apr; 27(4):526-32. PubMed ID: 10101148
[TBL] [Abstract][Full Text] [Related]
7. Uptake of glucuronides into isolated hepatocytes and their effects on glucuronide and sulphate conjugation.
Norling A; Andersson B; Berggren M; Moldéus P
Acta Pharmacol Toxicol (Copenh); 1978 Oct; 43(4):311-7. PubMed ID: 716948
[TBL] [Abstract][Full Text] [Related]
8. Comparison of in vitro preparations for semi-quantitative prediction of in vivo drug metabolism.
De Graaf IA; Van Meijeren CE; Pektaş F; Koster HJ
Drug Metab Dispos; 2002 Oct; 30(10):1129-36. PubMed ID: 12228190
[TBL] [Abstract][Full Text] [Related]
9. Development of a 19F-n.m.r. method for studies on the in vivo and in vitro metabolism of 2-fluoroaniline.
Vervoort J; De Jager PA; Steenbergen J; Rietjens IM
Xenobiotica; 1990 Jul; 20(7):657-70. PubMed ID: 2238701
[TBL] [Abstract][Full Text] [Related]
10. Metabolite kinetics of ondansetron in rat. Comparison of hepatic microsomes, isolated hepatocytes and liver slices, with in vivo disposition.
Worboys PD; Brennan B; Bradbury A; Houston JB
Xenobiotica; 1996 Sep; 26(9):897-907. PubMed ID: 8893037
[TBL] [Abstract][Full Text] [Related]
11. Metabolism of benzo[a]pyrene and (-)-trans-benzo[a]pyrene-7,8-dihydrodiol by freshly isolated hepatocytes from mirror carp.
Zaleski J; Steward AR; Sikka HC
Carcinogenesis; 1991 Feb; 12(2):167-74. PubMed ID: 1995182
[TBL] [Abstract][Full Text] [Related]
12. Metabolism of coumarin by precision-cut calf liver slices and calf liver microsomes.
Lake BG; Sauer MJ; Esclangon F; Beamand JA; Price RJ; Walters DG
Xenobiotica; 1995 Feb; 25(2):133-41. PubMed ID: 7618341
[TBL] [Abstract][Full Text] [Related]
13. In vitro metabolism of GV150013X by using liver microsomes and liver tissue slices from different species.
Kajbaf M; Rossato P; Ferrari L; Grossi P; Pellegatti M
Eur J Drug Metab Pharmacokinet; 1997; 22(4):359-66. PubMed ID: 9512935
[TBL] [Abstract][Full Text] [Related]
14. In vitro and in vivo metabolism of the progestagen Org 30659 in several species.
Verhoeven CH; Krebbers SF; Wagenaars GN; Booy CJ; Groothuis GM; Olinga P; Vos RM
Drug Metab Dispos; 1998 Nov; 26(11):1102-12. PubMed ID: 9806953
[TBL] [Abstract][Full Text] [Related]
15. Comparative metabolism of clenbuterol by rat and bovine liver microsomes and slices.
Zalko D; Perdu-Durand E; Debrauwer L; Bec-Ferte MP; Tulliez J
Drug Metab Dispos; 1998 Jan; 26(1):28-35. PubMed ID: 9443849
[TBL] [Abstract][Full Text] [Related]
16. In vivo clearance of ethoxycoumarin and its prediction from In vitro systems. Use Of drug depletion and metabolite formation methods in hepatic microsomes and isolated hepatocytes.
Carlile DJ; Stevens AJ; Ashforth EI; Waghela D; Houston JB
Drug Metab Dispos; 1998 Mar; 26(3):216-21. PubMed ID: 9492383
[TBL] [Abstract][Full Text] [Related]
17. Characterization of metronidazole metabolism by human liver microsomes.
Loft S; Otton SV; Lennard MS; Tucker GT; Poulsen HE
Biochem Pharmacol; 1991 Apr; 41(8):1127-34. PubMed ID: 2009091
[TBL] [Abstract][Full Text] [Related]
18. Cryopreservation of precision-cut rat liver slices using a computer-controlled freezer.
Maas WJ; Leeman WR; Groten JP; van de Sandt JJ
Toxicol In Vitro; 2000 Dec; 14(6):523-30. PubMed ID: 11033064
[TBL] [Abstract][Full Text] [Related]
19. Metabolism of coumarin and 7-ethoxycoumarin by rat, mouse, guinea pig, cynomolgus monkey and human precision-cut liver slices.
Steensma A; Beamand JA; Walters DG; Price RJ; Lake BG
Xenobiotica; 1994 Sep; 24(9):893-907. PubMed ID: 7810171
[TBL] [Abstract][Full Text] [Related]
20. Hydrogel embedding of precision-cut liver slices in a microfluidic device improves drug metabolic activity.
van Midwoud PM; Merema MT; Verweij N; Groothuis GM; Verpoorte E
Biotechnol Bioeng; 2011 Jun; 108(6):1404-12. PubMed ID: 21274846
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]