These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 8819850)

  • 1. Synthesis and 5HT modulating activity of stereoisomers of 3-phenoxymethyl-4-phenylpiperidines.
    Engelstoft M; Hansen JB
    Acta Chem Scand (Cph); 1996 Feb; 50(2):164-9. PubMed ID: 8819850
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Further SAR studies of piperidine-based analogues of cocaine. 2. Potent dopamine and serotonin reuptake inhibitors.
    Tamiz AP; Zhang J; Flippen-Anderson JL; Zhang M; Johnson KM; Deschaux O; Tella S; Kozikowski AP
    J Med Chem; 2000 Mar; 43(6):1215-22. PubMed ID: 10737754
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.
    Orjales A; Mosquera R; Toledo A; Pumar MC; García N; Cortizo L; Labeaga L; Innerárity A
    J Med Chem; 2003 Dec; 46(25):5512-32. PubMed ID: 14640559
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Further structure-activity relationship studies of piperidine-based monoamine transporter inhibitors: effects of piperidine ring stereochemistry on potency. Identification of norepinephrine transporter selective ligands and broad-spectrum transporter inhibitors.
    He R; Kurome T; Giberson KM; Johnson KM; Kozikowski AP
    J Med Chem; 2005 Dec; 48(25):7970-9. PubMed ID: 16335921
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 4-Piperidines and 3-pyrrolidines as dual serotonin and noradrenaline reuptake inhibitors: design, synthesis and structure-activity relationships.
    Fish PV; Andrews MD; Jonathan Fray M; Stobie A; Wakenhut F; Whitlock GA
    Bioorg Med Chem Lett; 2009 May; 19(10):2829-34. PubMed ID: 19359175
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, molecular docking and binding studies of selective serotonin transporter inhibitors.
    Nencetti S; Mazzoni MR; Ortore G; Lapucci A; Giuntini J; Orlandini E; Banti I; Nuti E; Lucacchini A; Giannaccini G; Rossello A
    Eur J Med Chem; 2011 Mar; 46(3):825-34. PubMed ID: 21272963
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of disubstituted piperidines and homopiperidines as potent dual NK1 receptor antagonists-serotonin reuptake transporter inhibitors for the treatment of depression.
    Wu YJ; He H; Bertekap R; Westphal R; Lelas S; Newton A; Wallace T; Taber M; Davis C; Macor JE; Bronson J
    Bioorg Med Chem; 2013 Apr; 21(8):2217-2228. PubMed ID: 23477943
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 5-HT reuptake inhibitors with 5-HT(1B/1D) antagonistic activity: a new approach toward efficient antidepressants.
    Matzen L; van Amsterdam C; Rautenberg W; Greiner HE; Harting J; Seyfried CA; Böttcher H
    J Med Chem; 2000 Mar; 43(6):1149-57. PubMed ID: 10737747
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Further studies on conformationally constrained tricyclic tropane analogues and their uptake inhibition at monoamine transporter sites: synthesis of (Z)-9-(substituted arylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes as a novel class of serotonin transporter inhibitors.
    Zhang A; Zhou G; Hoepping A; Mukhopadhyaya J; Johnson KM; Zhang M; Kozikowski AP
    J Med Chem; 2002 Apr; 45(9):1930-41. PubMed ID: 11960503
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Advances Toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT(1A) receptor antagonism/SSRI activities. Part 2.
    Takeuchi K; Kohn TJ; Honigschmidt NA; Rocco VP; Spinazze PG; Koch DJ; Atkinson ST; Hertel LW; Nelson DL; Wainscott DB; Ahmad LJ; Shaw J; Threlkeld PG; Wong DT
    Bioorg Med Chem Lett; 2003 Jul; 13(14):2393-7. PubMed ID: 12824042
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design and synthesis of promiscuous high-affinity monoamine transporter ligands: unraveling transporter selectivity.
    Greiner E; Boos TL; Prisinzano TE; De Martino MG; Zeglis B; Dersch CM; Marcus J; Partilla JS; Rothman RB; Jacobson AE; Rice KC
    J Med Chem; 2006 Mar; 49(5):1766-72. PubMed ID: 16509591
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological properties of new 2beta-alkyl- and 2beta-aryl-3-(substituted phenyl)tropane derivatives: stereochemical effect of C-3 on affinity and selectivity for neuronal dopamine and serotonin transporters.
    Kozikowski AP; Araldi GL; Prakash KR; Zhang M; Johnson KM
    J Med Chem; 1998 Dec; 41(25):4973-82. PubMed ID: 9836615
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and molecular modeling of new 1-aryl-3-[4-arylpiperazin-1-yl]-1-propane derivatives with high affinity at the serotonin transporter and at 5-HT(1A) receptors.
    Orús L; Pérez-Silanes S; Oficialdegui AM; Martínez-Esparza J; Del Castillo JC; Mourelle M; Langer T; Guccione S; Donzella G; Krovat EM; Poptodorov K; Lasheras B; Ballaz S; Hervías I; Tordera R; Del Río J; Monge A
    J Med Chem; 2002 Sep; 45(19):4128-39. PubMed ID: 12213056
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Synthesis and antidepressant activities of aryl alkanol piperidine derivatives].
    Zheng YY; Gao K; Weng ZJ; Li JQ
    Yao Xue Xue Bao; 2010 Mar; 45(3):324-9. PubMed ID: 21351508
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of DSP-1053, a novel benzylpiperidine derivative with potent serotonin transporter inhibitory activity and partial 5-HT
    Yoshinaga H; Nishida T; Sasaki I; Kato T; Oki H; Yabuuchi K; Toyoda T
    Bioorg Med Chem; 2018 May; 26(8):1614-1627. PubMed ID: 29456112
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and Synthesis of Arylamidine Derivatives as Serotonin/Norepinephrine Dual Reuptake Inhibitors.
    Wen H; Qin W; Yang G; Guo Y
    Molecules; 2019 Jan; 24(3):. PubMed ID: 30704101
    [TBL] [Abstract][Full Text] [Related]  

  • 17. N-Alkyl-N-arylmethylpiperidin-4-amines: novel dual inhibitors of serotonin and norepinephrine reuptake.
    Boot JR; Boulet SL; Clark BP; Cases-Thomas MJ; Delhaye L; Diker K; Fairhurst J; Findlay J; Gallagher PT; Gilmore J; Harris JR; Masters JJ; Mitchell SN; Naik M; Simmonds RG; Smith SM; Richards SJ; Timms GH; Whatton MA; Wolfe CN; Wood VA
    Bioorg Med Chem Lett; 2006 May; 16(10):2714-8. PubMed ID: 16497500
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition.
    Fish PV; Deur C; Gan X; Greene K; Hoople D; Mackenny M; Para KS; Reeves K; Ryckmans T; Stiff C; Stobie A; Wakenhut F; Whitlock GA
    Bioorg Med Chem Lett; 2008 Apr; 18(8):2562-6. PubMed ID: 18387300
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of the first potent, selective 5-hydroxytryptamine1D receptor antagonist.
    Ward SE; Harrington FP; Gordon LJ; Hopley SC; Scott CM; Watson JM
    J Med Chem; 2005 May; 48(10):3478-80. PubMed ID: 15887956
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New 1-aryl-3-(4-arylpiperazin-1-yl)propane derivatives, with dual action at 5-HT1A serotonin receptors and serotonin transporter, as a new class of antidepressants.
    Martínez-Esparza J; Oficialdegui AM; Pérez-Silanes S; Heras B; Orús L; Palop JA; Lasheras B; Roca J; Mourelle M; Bosch A; Del Castillo JC; Tordera R; Del Río J; Monge A
    J Med Chem; 2001 Feb; 44(3):418-28. PubMed ID: 11462981
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.